Patents by Inventor Jihua Guan

Jihua Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
    Patent number: 8586616
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: November 19, 2013
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
  • NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20110086883
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 14, 2011
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, JR.
  • Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
    Patent number: 7879895
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: February 1, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
  • NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20100298383
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: August 3, 2010
    Publication date: November 25, 2010
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, JR.
  • Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
    Patent number: 7795446
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: September 14, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
  • Novel Benzimidazole Derivatives Useful as Selective Androgen Receptor Modulators (SARMS)
    Publication number: 20090258909
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: June 22, 2009
    Publication date: October 15, 2009
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, JR.
  • Benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
    Patent number: 7566733
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: July 28, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
  • NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)
    Publication number: 20080119522
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: January 25, 2008
    Publication date: May 22, 2008
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James Lanter, Vernon Alford
  • Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
    Patent number: 7348438
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: March 25, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
  • Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
    Publication number: 20060116412
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: September 26, 2005
    Publication date: June 1, 2006
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James Lanter, Vernon Alford
  • Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
    Publication number: 20060111402
    Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: September 26, 2005
    Publication date: May 25, 2006
    Inventors: Raymond Ng, Zhihua Sui, Jihua Guan, James Lanter, Vernon Alford
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Publication number: 20050113402
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Application
    Filed: October 22, 2004
    Publication date: May 26, 2005
    Inventors: Zhihua Sui, Mark Macielag, Jihua Guan, Weigin Jiang, James Lanter
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Patent number: 6818646
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: November 16, 2004
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weigin Jiang, James C. Lanter
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Publication number: 20040044021
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): 1
    Type: Application
    Filed: August 11, 2003
    Publication date: March 4, 2004
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weigin Jiang, James C. Lanter
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Patent number: 6635638
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: October 21, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weiqin Jiang, James C. Lanter
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Publication number: 20020010183
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): 1
    Type: Application
    Filed: May 2, 2001
    Publication date: January 24, 2002
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weiqin Jiang, James C. Lanter
  • 5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the treatment of male erectile dysfunction
    Patent number: 6077841
    Abstract: The invention is directed to novel substituted 5-heterocyclyl pyrazolopyrimidinones and derivatives thereof, their synthesis and their use in treating sexual dysfunction in mammals, especially male erectile dysfunction. Pharmaceutical compositions containing the compounds and methods of using them to treat sexual dysfunction are also described.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: June 20, 2000
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Zhihua Sui, Jihua Guan, Mark J. Macielag