Patents by Inventor Jing Ting Christine Yuan
Jing Ting Christine Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12234220Abstract: Disclosed are immunomodulatory compounds, pharmaceutical compositions containing them, and methods of making and using the compounds to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.Type: GrantFiled: June 27, 2019Date of Patent: February 25, 2025Assignee: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan, Hu Liu
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Patent number: 12227488Abstract: Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that may cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders characterized or mediated by aberrant protein activity.Type: GrantFiled: December 3, 2019Date of Patent: February 18, 2025Assignee: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Alyssa Verano, Eric Wang, Radoslaw Nowak, Jing Ting Christine Yuan, Nathanael Gray, Eric Fischer, Tinghu Zhang, Hu Liu
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Patent number: 12110292Abstract: Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.Type: GrantFiled: November 11, 2022Date of Patent: October 8, 2024Assignee: Dana-Farber Cancer Institute, Inc.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Patent number: 12060366Abstract: Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.Type: GrantFiled: June 27, 2019Date of Patent: August 13, 2024Assignee: Dana-Farber Cancer Institute, Inc.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Patent number: 12030892Abstract: Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by dysregulated or dysfunctional protein activity that can be targeted by cereblon.Type: GrantFiled: June 27, 2019Date of Patent: July 9, 2024Assignee: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Publication number: 20230312575Abstract: Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.Type: ApplicationFiled: November 11, 2022Publication date: October 5, 2023Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Patent number: 11530219Abstract: Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.Type: GrantFiled: June 27, 2019Date of Patent: December 20, 2022Assignee: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Publication number: 20220177443Abstract: Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that may cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders characterized or mediated by aberrant protein activity.Type: ApplicationFiled: December 3, 2019Publication date: June 9, 2022Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Alyssa Verano, Eric Wang, Radoslaw Nowak, Jing Ting Christine Yuan, Nathanael Gray, Eric Fischer, Tinghu Zhang, Hu Liu
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Publication number: 20210300941Abstract: Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.Type: ApplicationFiled: June 27, 2019Publication date: September 30, 2021Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Publication number: 20210292325Abstract: Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.Type: ApplicationFiled: June 27, 2019Publication date: September 23, 2021Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
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Publication number: 20210284624Abstract: Disclosed are immunomodulatory compounds, pharmaceutical compositions containing them, and methods of making and using the compounds to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.Type: ApplicationFiled: June 27, 2019Publication date: September 16, 2021Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan, Hu Liu
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Publication number: 20210277018Abstract: Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by dysregulated or dysfunctional protein activity that can be targeted by cereblon.Type: ApplicationFiled: June 27, 2019Publication date: September 9, 2021Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael Gray, Tinghu Zhang, Eric Fischer, Alyssa Verano, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan