Abstract: The present invention relates to a method and system for identifying the movement of a substance across a biological barrier using diffusion magnetic resonance imaging (dMRI). The method involves administering an exogenous substance to a subject undergoing imaging, and then obtaining one or more images of targeted regions post-administration using dMRI. The images are analyzed to characterize changes in diffusivity, permeability, or diffusion tensor parameters, enabling the determination of the transport of the exogenous substance through the biological barrier.

Abstract: A method for detecting blood-tissue barrier breakdown or disruption is provided. The method includes acquiring first image data of a target region of a subject with a predetermined spatial resolution; administrating exogenous or endogenous tracer into the subject; acquiring second image data of the target region with the predetermined spatial resolution after administration of the tracer; differentiating healthy tissue and pathological tissue with blood-tissue barrier breakdown in the target region based on the first image data and the second image data; and visualizing or analyzing the blood-tissue barrier breakdown of pathological tissue based on the differentiation.

Abstract: A method for obtaining a magnetic resonance imaging (MRI) image of an object is provided. The method includes applying a MRI sequence to a target area in the object, receiving magnetic resonance (MR) signals from the target area, acquiring, in one k-space strategy, a first set of k-space lines based on the MR signals while nuclear spins in the target area are in a transient state, acquiring, in another k-space strategy, a second set of k-space lines based on the MR signals while the nuclear spins in the target area are in a steady-state or a mixed state of the transient state and the steady-state, and reconstructing the MRI image based on the first set of k-space lines and the second set of k-space lines.

Abstract: The disclosure discloses a fusion albumin nanoparticle and application thereof, and belongs to the technical field of biomedicine. In the disclosure, fusion albumin is expressed by using a genetic engineering technology, and the fusion albumin nanoparticle is formed by performing self-assembly and drug loading on the fusion albumin in a neutral aqueous solution. The fusion albumin studied in the disclosure has targetability, pH and enzyme-sensitive functional groups, the nanoparticle prepared by using the fusion albumin has the functions of targetability and controlled drug release, and a method for preparing the fusion albumin nanoparticle is simple and easy to implement and has great application potential.

Abstract: An image processing method and apparatus. The method includes: determining color values of original pixels in an original color image, where for each of the original pixels, the original pixel includes N original sub-pixels corresponding to different basic colors of a color model respectively, a color value of the original pixel includes color components of the basic colors corresponding to the N original sub-pixels, and N is a positive integer greater than 1; generating mixed images corresponding to the N basic colors respectively according to the color values of the original pixels, where N original pixels in the original color image corresponding one-by-one to N mixed sub-pixels in the mixed pixel are determined, and color components of the basic color in the color values of the N original pixels are determined as color components corresponding to the N mixed sub-pixels respectively.

Abstract: Aspects and embodiments herein pertain to global ML prediction applied in a data security context. In some examples, a global prediction pertaining to a data item as a whole (the ‘original’ data item) is generated using an ML predictor. A data element is masked by removing it from the data item, or obscuring it in some way (e.g., through modification or replacement). The same ML predictor is applied to the perturbed data item. A change in global confidence between the original data item and the perturbed data item denotes local significance of the individual data item (or subset of data items) that have been masked. Other significance indicators (such as start and end markers of significant sections) are also considered. Other methods of estimating local significance are considered. In some examples, one or more such methods are used to generate training data for training a self-interpretation ML model.

Abstract: A data transmission method includes: capturing, by a virtual reality host, a portion of an image to be transmitted in a preset area to obtain a first image, and compressing, by the virtual reality host, a portion of the image to be transmitted in a display area to obtain a second image, wherein the preset area is a portion of the display area (S101); transmitting, by the virtual reality host, the first image and the second image to a virtual reality apparatus in a certain order (S102); receiving the first image and the second image by the virtual reality apparatus (S103); stretching the second image by the virtual reality apparatus, and merging the first image with a stretched second image by the virtual reality apparatus to obtain an image to be displayed (S104); and displaying the image to be displayed by the virtual reality apparatus (S105).

Abstract: The invention provides an oligosaccharide-fluorescent marker, and a preparation method and use thereof. The method includes reacting an oligosaccharide with a fluorescent agent in a solvent in the presence of a reducing agent to obtain the oligosaccharide-fluorescent marker. According to the oligosaccharide-fluorescent marker of the invention, an amino group in the fluorescent agent is subjected to a condensation reaction with a hemiacetal group at a reducing end of the oligosaccharide, to form an imine or Schiff base, and then the imine or Schiff base is reduced into a relatively stable secondary amine by using the reducing agent. In this way, the end of the oligosaccharide is fluorescently marked. The fluorescent group marked at the end has small influence on the biological activity of the oligosaccharide, and the marker has higher fluorescence intensity and is stable under physiological conditions.

Abstract: A method for spatial resolution enhanced imaging is provided. The method includes determining a target region of a subject being imaged; estimating an achievable spatial resolution; selecting an increased spatial resolution that is greater than a predetermined spatial resolution and equal to or less than the achievable spatial resolution; and acquiring image data of the target region with the increased spatial resolution. A method for enhancing the contrast between the region of interest and other tissue region in the image data acquired with the increased spatial resolution and other tissue region in image data acquired with the predetermined spatial resolution due to the intrinsic partial volume effect is also provided.

Abstract: A micro light-emitting device includes a semiconductor epitaxial structure having a bottom surface and a top surface opposite to each other, and including a first cladding layer, an active layer, and a second cladding layer disposed sequentially in such order in a direction from the bottom surface to the top surface. At least one of the first and second cladding layers has a super-lattice structure. The super-lattice structure of the first cladding layer includes first sublayers and second sublayers stacked alternately. Each first sublayer includes Alx1Ga1-x1InP, and each second sublayer includes Alx2Ga1-x2InP, where 0<x1<x2?1. The super-lattice structure of the second cladding layer including third sublayers and fourth sublayers stacked alternately. Each third sublayer includes Alz1Ga1-z1InP, and each fourth sublayer includes Alz2Ga1-z2InP, where 0<z1<z2?1.

Abstract: A method or system for assessing a patient response to a cancer treatment is provided. The method or system includes acquiring at least one base-line radiological image related to a patient immediately before a treatment, acquiring at least one follow-up radiological image during or after the treatment at a predetermined time interval, estimating a first number of specific tumor cells in a region of interest of the patient based on image features of the base-line radiological image using an algorithm or a model, estimating a second number of specific tumor cells in the region of interest of the patient based on image features of the follow-up radiological image using the algorithm or the model, obtaining a difference between the first number of specific tumor cells and the second number of specific tumor cells, and classifying a treatment response to a cancer based on the difference.

Abstract: A magnet resonance system including a magnet, gradient coils, and radiofrequency coils. The gradient coils have one or more first electrically conductive loops that provide spatial encoding as to a subject of the system. The radiofrequency coils have one or more second electrically conductive loops that transmit a radiofrequency field to excite nuclear spins and/or receive an MRI signal. All or a portion of the one or more first electrically conductive loops and the one or more second electrically conductive loops are shared. The present teachings provide a device that integrates part of one or more gradient coils into part of one or more RF coils in a magnetic resonance system.

Abstract: The present disclosure provides an ecological governance method based on erosion prevention and control for a gentle slope farmland and relates to the technical field of ecological governance of farmlands. The ecological governance method based on erosion prevention and control for a gentle slope farmland includes the following steps: sampling a gentle slope farmland to investigate erosion thereof; and determining erosion of a gentle slope cultivated land and selecting a corresponding recovery strategy based on a detection result of a sample, a soil quality index (SQI), and a comprehensive vegetation quality index (VQI), where the recovery strategy includes a natural recovery method and a biological-farming comprehensive recovery method; enclosing the gentle slope cultivated land, fallowing the gentle slope cultivated land and reducing tillage; exterminating insect pests and poisonous weeds in the enclosed area; and turning over straws under soil by a cultivator. The growth of poisonous weeds is inhibited.

Abstract: A radio-frequency apparatus for magnetic resonance imaging (MRI) and/or magnetic resonance spectroscopy (MRS) transmission comprising: at least one first coil resonator and at least one second coil resonator including a plurality of conductive elements, one or more of capacitive elements in each of the at least one first coil resonator and the at least one second coil resonator; the first and second coil resonators are located in a same layer of the radio-frequency apparatus with a same mode, are parallel to an axis of the subject being imaged and are electromagnetically isolated relative to each other; major components of radio-frequency fields generated by the first and second coil resonators extend in a direction that is orthogonal and perpendicular to a main magnetic field; and a combination of the first and second coil resonators are a radio-frequency apparatus to excite nuclear spins for the MRI and the MRS.

Abstract: The present disclosure relates to a method and a system for minimizing electromagnetic interference (EMI) of magnetic resonance imaging (MRI) systems in complex electromagnetic environments. The method and system described herein provide superior MRI image quality and may reduce costs by eliminating the requirement of expensive shielding in MRI systems/hybrid MRI systems.

Abstract: The present disclosure relates to a method and a system for minimizing electromagnetic interference (EMI) of magnetic resonance imaging (MRI) systems in complex electromagnetic environments. The method and system described herein provide superior MRI image quality and may reduce costs by eliminating the requirement of expensive shielding in MRI systems/hybrid MRI systems.

Abstract: A method for motion correction of Magnetic Resonance (MR) images is provided. The method includes acquiring a k-space dataset for an object using an MR scanner, detecting or identifying corrupted k-space data from the acquired k-space dataset, extracting the corrupted k-space data from the acquired k-space dataset, recovering the corrupted k-space data, combining uncorrupted k-space data of the acquired k-space dataset with the recovered k-space data to form a full k-space dataset, and reconstructing an image for the object based on the full k-space dataset. A magnetic resonance imaging system for correcting corrupted k-space data of an entire k-space dataset is also provided.

Abstract: A method or system for assessing a patient response to a cancer treatment is provided. The method or system includes acquiring at least one base-line radiological image related to a patient immediately before a treatment, acquiring at least one follow-up radiological image during or after the treatment at a predetermined time interval, estimating a first number of specific tumor cells in a region of interest of the patient based on image features of the base-line radiological image using an algorithm or a model, estimating a second number of specific tumor cells in the region of interest of the patient based on image features of the follow-up radiological image using the algorithm or the model, obtaining a difference between the first number of specific tumor cells and the second number of specific tumor cells, and classifying a treatment response to a cancer based on the difference.

Abstract: A method for k-space registration is provided. The method of k-space registration includes receiving a first partial k-space dataset for an object and a second partial k-space dataset for the object, selecting the first partial k-space dataset as a reference, selecting feature for estimating a transformation matrix for transforming k-space data, estimating a transformation matrix based on the feature of entire or part of the first partial k-space dataset and the feature of the second partial k-space dataset corresponding to the entire or part of the first partial k-space dataset, correcting the second partial k-space dataset based on the transformation matrix, and obtaining the corrected second partial k-space dataset. The present method is further used for partial Fourier reconstruction.

Abstract: Described herein are polyclonal and monoclonal antibodies that binds to VSIG3, compounds that modulate the interaction of VISTA and VSIG3, and methods of making and using the polyclonal and monoclonal antibodies and compounds. Also described herein are methods that include modulating the interaction of VISTA and VSIG3 by introducing a compound that modulates the interaction of VISTA and SIG3.