Patents by Inventor Jinhua Chen

Jinhua Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180255832
    Abstract: An atomizer compartment structure includes an oil storage compartment and a heating core support. The upper end of the oil storage tank is a closed end, and the lower end of the oil storage tank has a tubular oil conduit and an air conduit, and the external wall of the oil storage compartment has a latch buckle disposed at an end near the air conduit. The upper end of the heating core support has an oil filling hole corresponsive to the oil conduit and an air guide hole corresponsive to the air conduit, and the external wall of the heating core support has an engaging slot for engaging the latch buckle. When the oil storage compartment and the heating core support are latched tightly, the oil conduit extends into the oil filling hole and the air conduit extends into the air guide hole.
    Type: Application
    Filed: August 23, 2017
    Publication date: September 13, 2018
    Inventors: Zeqi Wang, Jinhua Chen, Haiyuan Wang
  • Publication number: 20180208549
    Abstract: Provided are a new aromatic cyanogen compound and a preparation method thereof. The present invention also relates to the use of such compound in antiviral drugs, in particular the use thereof in anti-HCV drugs.
    Type: Application
    Filed: August 17, 2016
    Publication date: July 26, 2018
    Inventors: Yanping Li, Zhuorong Li, Zonggen Peng, Jianrui Li, Xinbei Jiang, Jinhua Chen, Jiandong Jiang
  • Publication number: 20180154943
    Abstract: A vehicle engine compartment assembly includes an upper longitudinal beam and a front subframe disposed under the upper longitudinal beam. The vehicle engine compartment assembly further includes a middle longitudinal beam and a connecting supporting member. The middle longitudinal beam is disposed between the upper longitudinal beam and the front subframe. The connecting supporting member is connected to each of the middle longitudinal beam, the upper longitudinal beam and the front subframe. In the vehicle engine compartment assembly, the middle longitudinal beam is added between the upper longitudinal beam and the front subframe, and the upper longitudinal beam, the middle longitudinal beam and the front subframe are connected together to form a stable structure having a shape of “”. When the vehicle suffers collision at a high speed, the impact force is transferred through three load transfer paths to improve the energy absorption effect.
    Type: Application
    Filed: November 5, 2015
    Publication date: June 7, 2018
    Applicant: Guangzhou Automobile Group Co.,Ltd.
    Inventors: XIANGDONG HUANG, PENG YUE, HUANQUAN YUAN, FURONG GENG, JINHUA CHEN
  • Patent number: 9950144
    Abstract: An apparatus for delivering devices. The apparatus comprises a catheter with an elongated shaft having a first lumen and a second lumen extending therethrough. The apparatus further comprises a distal section with a lumen in communication with a port in a distal end of the catheter and with the first lumen and the second lumen. The first lumen is configured for a first device and the second lumen is configured for a second device to be disposed therein. The apparatus further comprises a proximal adapter coupled to the elongated shaft with a first port in communication with the first lumen and a second port in communication with the second lumen.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: April 24, 2018
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Mina Chow, Dwight A. Ambat, Jinhua Chen, Eugene T. Michal
  • Publication number: 20170112891
    Abstract: The invention relates generally to disulfide drug conjugates wherein a linker comprising a sulfur-bearing carbon atom substituted with at least one hydrocarbyl or substituted hydrocarbyl is conjugated by a disulfide bond to a cysteine sulfur atom of a targeting carrier, and wherein the linker is further conjugated to a drug moiety. The invention further relates to activated linker-drug conjugates suitable for conjugation to a targeting carrier by a disulfide bond. The invention further relates to methods for preparing hindered disulfide drug conjugates.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 27, 2017
    Inventors: Peter Dragovich, Zhonghua Pei, Thomas Pillow, Jack Sadowsky, Jinhua Chen, John Wai
  • Publication number: 20170001990
    Abstract: The invention provides novel compounds having the general formula: and tautomers and pharmaceutically acceptable salts thereof, wherein A1, A2, A3, A4, R1, R4, R5, R6, R7 and R8 are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: September 15, 2016
    Publication date: January 5, 2017
    Applicant: Genentech, Inc.
    Inventors: Jinhua CHEN, Charles Z. DING, Peter DRAGOVICH, Benjamin FAUBER, Zhenting GAO, Sharada S. LABADIE, Kwong Wah LAI, Hans Edward PURKEY, Kirk ROBARGE, Binqing WEI, Aihe ZHOU
  • Patent number: 9314712
    Abstract: The current invention provides compositions, which are useful as stationary phases for a variety of chromatographic applications, such as high performance liquid chromatography (HPLC) and solid-phase extraction (SPE). The compositions include a porous solid support (e.g., silica gels, silica monoliths or synthetic organic resins) having an exterior surface and pore openings defined by “interior walls”. To the solid support are covalently bound organic ion-exchange ligands (e.g., silyl ligands), which incorporate at least one ion-exchange group (e.g., ionic or ionizable group). The compositions further include micro-particles (e.g., latex particles) incorporating ion-exchange groups having a charge that is opposite to the charge found on the support. The micro-particles are bound to the exterior surface of the support (e.g., via electrostatic forces).
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: April 19, 2016
    Assignee: DIONEX CORPORATION
    Inventors: Xiaodong Liu, Christopher A. Pohl, Jinhua Chen, L. Andy Woodruff
  • Patent number: 9310344
    Abstract: The present invention provides an agglomerated multimodal chromatographic medium. the medium of the invention includes groups active in anion exchange, cation exchange and hydrophilic interaction chromatographic modalities. The invention provides methods of making these media and using them in separations of analytes. Also provided are separations devices incorporating the medium and systems incorporating these separations devices.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: April 12, 2016
    Assignee: DIONEX CORPORATION
    Inventors: Xiaodong Liu, Christopher A. Pohl, Jinhua Chen
  • Publication number: 20160008578
    Abstract: An apparatus for delivering devices. The apparatus comprises a catheter with an elongated shaft having a first lumen and a second lumen extending therethrough. The apparatus further comprises a distal section with a lumen in communication with a port in a distal end of the catheter and with the first lumen and the second lumen. The first lumen is configured for a first device and the second lumen is configured for a second device to be disposed therein. The apparatus further comprises a proximal adapter coupled to the elongated shaft with a first port in communication with the first lumen and a second port in communication with the second lumen.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 14, 2016
    Inventors: Mina Chow, Dwight A. Ambat, Jinhua Chen, Eugene T. Michal
  • Patent number: 9144756
    Abstract: The current invention provides compositions, which are useful as stationary phases for a variety of chromatographic applications, such as high performance liquid chromatography (HPLC) and solid-phase extraction (SPE). The compositions provide both strong aromatic and hydrophobic interactions with components of a sample. Moreover, the invention provides compositions of new silanes, their immobilization on a solid substrate, such as silica, to form new stationary phases.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: September 29, 2015
    Assignee: Dionex Corporation
    Inventors: Xiaodong Liu, Jinhua Chen, Christopher A. Pohl
  • Publication number: 20140370614
    Abstract: The present invention provides an agglomerated multimodal chromatographic medium. the medium of the invention includes groups active in anion exchange, cation exchange and hydrophilic interaction chromatographic modalities. The invention provides methods of making these media and using them in separations of analytes. Also provided are separations devices incorporating the medium and systems incorporating these separations devices.
    Type: Application
    Filed: June 14, 2013
    Publication date: December 18, 2014
    Inventors: Xiaodong LIU, Christopher A. POHL, Jinhua CHEN
  • Publication number: 20130237112
    Abstract: With respect to the anionic polymer ion-exchange material used in an alkaline fuel cell, an electrodialysis apparatus, water treatment industry, catalyst industry, and the like, there are provided an anionic polymer ion-exchange material having both excellent ionic conductivity and excellent mechanical strength, as compared to the materials conventionally used, and a method for producing the same. An anionic polymer ion-exchange material having a polymer base material mainly made of an amide resin having both an aromatic structure and an aliphatic chain in the principal chain thereof, wherein the polymer base material has an anionic monomer graft-polymerized on the aliphatic chain in the principal chain of the amide resin, wherein the anionic monomer has an aromatic structure and a quaternary ammonium structure.
    Type: Application
    Filed: February 27, 2013
    Publication date: September 12, 2013
    Applicant: JAPAN ATOMIC ENERGY AGENCY
    Inventors: Jinhua CHEN, Masaharu ASANO, Yasunari MAEKAWA
  • Patent number: 8372558
    Abstract: A vinyl monomer is graft polymerized on an aromatic hydrocarbon-based polymer film substrate to introduce graft chains into the substrate and thereafter a functional monomer represented by the following formula and having sulfonic acid groups or functional groups capable of conversion to sulfonic acid groups is graft polymerized to introduce the sulfonic acid groups or the functional groups capable of conversion to sulfonic acid groups: where R is an aromatic ring or an aliphatic chain; X is (1) —OH, (2) —OLi, —ONa or —OK, (3) —F or —Cl, or (4) —OCnH2n+1 where n is an integer of 1 to 7. Since the graft chains obtained by graft polymerization of the vinyl monomer can also be utilized as scaffold polymers, the graft polymerizability of the functional monomer to the aromatic hydrocarbon-based polymer film substrate is sufficiently improved to enable the preparation of a polymer electrolyte membrane that excels not only in proton conductivity and mechanical strength but also in dimensional stability.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: February 12, 2013
    Assignee: Japan Atomic Energy Agency
    Inventors: Jinhua Chen, Yasunari Maekawa, Masaharu Asano, Masaru Yoshida
  • Patent number: 8283088
    Abstract: An object is to provide an electrolyte membrane that maintains excellent cell characteristics for a long time under high temperature and low water retention, as this is the most important point in fuel cells. A process for producing a polymer electrolyte membrane for fuel cells is provided, which process comprises in sequence: forming graft molecular chains by graft-polymerization of a vinyl silane coupling agent on a polymer film substrate that has phenyl groups capable of holding sulfonic acid groups; introducing sulfonic acid groups into phenyl groups contained in the graft molecular chains; and hydrolyzing and condensing alkoxy groups contained in the graft molecular chains so that a silane crosslinked structure is introduced between the graft molecular chains. A polymer electrolyte membrane produced by the process is also provided.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: October 9, 2012
    Assignees: Japan Atomic Energy Agency, Nitto Denko Corporation
    Inventors: Masaru Yoshida, Masaharu Asano, Jinhua Chen, Yasunari Maekawa, Toshimitsu Tachibana, Yozo Nagai, Soji Nishiyama
  • Patent number: 8129074
    Abstract: A crosslinked nano-inorganic particle/polymer electrolyte membrane composed of a polymer film substrate, graft molecular chains bound to the backbone skeleton of the polymer film substrate and comprising a vinyl monomer graft-polymerized, sulfonic groups bound to the graft molecular chains, and an inorganic material as nano-scale particles uniformly dispersed within a crosslinked structure ascribed to the backbone skeleton of the polymer film substrate and the graft molecular chains, wherein the backbone skeleton of the polymer film substrate, the graft molecular chains, and the nano-inorganic particles mutually construct a crosslinked structure.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: March 6, 2012
    Assignees: Japan Atomic Energy Agency, Nitto Denko Corporation
    Inventors: Jinhua Chen, Masaru Yoshida, Masaharu Asano, Tetsuya Yamaki, Toshimitsu Tachibana, Soji Nishiyama, Yozo Nagai
  • Publication number: 20110284465
    Abstract: The current invention provides compositions, which are useful as stationary phases for a variety of chromatographic applications, such as high performance liquid chromatography (HPLC) and solid-phase extraction (SPE). The compositions provide both strong aromatic and hydrophobic interactions with components of a sample. Moreover, the invention provides compositions of new silanes, their immobilization on a solid substrate, such as silica, to form new stationary phases.
    Type: Application
    Filed: May 19, 2011
    Publication date: November 24, 2011
    Applicant: Dionex Corporation
    Inventors: Xiaodong Liu, Jinhua Chen, Christopher A. Pohl
  • Patent number: 7993793
    Abstract: By performing photograft polymerization of functional monomers such that grafted chains will be introduced from the surface of a polymer base film into its interior without deteriorating its inherent characteristics and also by creating a multiplex crosslinked structure between the grafted chains and the base film under such conditions as to cause preferential radiation-induced crosslinking reaction, there is produced a polymer electrolyte membrane having high enough oxidation resistance and proton conductivity to be suitable for use in fuel cells.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: August 9, 2011
    Assignees: Japan Atomic Energy Agency, Nitto Denko Corporation
    Inventors: Masaru Yoshida, Masaharu Asano, Jinhua Chen, Yasunari Maekawa, Toshimitsu Tachibana, Yozo Nagai, Soji Nishiyama
  • Patent number: 7932245
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: April 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Youssef L. Bennani, William H. Bunnelle, Sou-Jen Chang, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Dilinie P. Fernando, Yi-Yin Ku, Mark Lockwood, Lei Wang
  • Publication number: 20100190875
    Abstract: An aromatic polymer film substrate, or a grafted aromatic polymer film substrate having a monomer introduced therein as graft chains is irradiated with ionizing radiation to impart a crosslinked structure. The aromatic polymer film substrate or the grafted aromatic polymer film substrate, provided with the crosslinked structure, is directly sulfonated to obtain a crosslinked aromatic polymer electrolyte membrane. The crosslinked aromatic polymer electrolyte membrane has low water uptake, high proton conductivity, low methanol permeability, high chemical stability, and excellent mechanical characteristics.
    Type: Application
    Filed: April 1, 2010
    Publication date: July 29, 2010
    Applicant: JAPAN ATOMIC ENERGY AGENCY
    Inventors: Jinhua Chen, Yasunari Maekawa, Masaharu Asano, Masaru Yoshida
  • Patent number: 7714027
    Abstract: An aromatic polymer film substrate, or a grafted aromatic polymer film substrate having a monomer introduced therein as graft chains is irradiated with ionizing radiation to impart a crosslinked structure. The aromatic polymer film substrate or the grafted aromatic polymer film substrate, provided with the crosslinked structure, is directly sulfonated to obtain a crosslinked aromatic polymer electrolyte membrane. The crosslinked aromatic polymer electrolyte membrane has low water uptake, high proton conductivity, low methanol permeability, high chemical stability, and excellent mechanical characteristics. A method for producing the crosslinked aromatic polymer electrolyte membrane is also provided.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: May 11, 2010
    Assignee: Japan Atomic Energy Agency
    Inventors: Jinhua Chen, Yasunari Maekawa, Masaharu Asano, Masaru Yoshida