Patents by Inventor Jochen Franke

Jochen Franke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210116525
    Abstract: A hybrid imaging apparatus for imaging an object to be examined located in a sample volume can be operated in an MPI mode and in at least one further imaging mode and comprises a magnet arrangement embodied to generate, in the MPI mode, a magnetic field with a gradient B1 and a field-free region in the sample volume, wherein the magnet arrangement comprises a ring magnet pair with two ring magnets in a Halbach dipole configuration, which are arranged coaxially on a common Z-axis that extends through the sample volume, wherein the ring magnets are arranged so as to be twistable relative to one another about the Z-axis. Consequently, it is possible to generate magnetic fields that meet the requirements of both MRI and MPI such that the hybrid imaging apparatus can be equipped for measurements in various imaging modes, including MPI, MRI and CT.
    Type: Application
    Filed: October 19, 2020
    Publication date: April 22, 2021
    Inventors: Jochen FRANKE, Volker NIEMANN
  • Patent number: 10796465
    Abstract: A method for establishing and/or reducing artifacts that arise when reconstructing (R) an MPI overall image data record from MPI signal data and an appended system matrix (SMapp(r,f)), wherein the appended system matrix (SMapp(r,f)) includes system matrices of different particle classes (P1, P2). The method includes setting a selection region (cvn(r)) of a reconstructed MPI overall image data record (cn(r)), producing virtual signal data (sn(f)) by inverse transformation of the selection region, reconstructing a virtual overall image data record (c?vn(r)) from the virtual signal data and the appended system matrix, setting an artifact region (cartifact_n(r)) within the reconstructed virtual overall image data record so that the artifact region has only voxels lying outside of the selection region, and assigning the image data present in the artifact region as artifact image data (cartifact_n(r)). This permits ghost artifacts to be corrected.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 6, 2020
    Assignee: BRUKER BIOSPIN MRI GMBH
    Inventors: Jochen Franke, Michael Herbst
  • Patent number: 10782367
    Abstract: A method for establishing a local concentration distribution of magnetic particles of at least one particle class within an examination volume or a variable derived from this concentration distribution. The method includes providing at least one system matrix, providing MPI signal data of at least one sample including magnetic particles of at least one particle class within a measurement volume, and reconstructing spatially resolved MPI image data from the provided MPI signal data. At least one spatial projection of at least one part of the system matrix is carried out along a projection direction and a projected system matrix is generated thereby. The reconstruction of the MPI image data is implemented with the at least partly projected system matrix, as a result of which MPI image data of a spatial projection of the local concentration distribution of the magnetic particles are produced along the projection direction.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: September 22, 2020
    Assignee: BRUKER BIOSPIN MRI GMBH
    Inventors: Jochen Franke, Michael Herbst
  • Publication number: 20200026159
    Abstract: An objective lens main body and an objective lens system formed by the objective lens are provided. The objective lens main body includes a main frame for retaining optical functional elements and at least one adjustable, optical functional element that is retained adjustably thereon. The objective lens main body furthermore includes at least one adjustment drive arranged on the main frame for adjusting the adjustable functional element or at least one of the adjustable functional elements. In addition, the objective lens main body includes an electronics board attached indirectly or directly to the main frame that has at least one plug-in location for reversibly receiving a plug-in card, and a first controller that is configured as a plug-in card and inserted into the plug-in location or one of the plug-in locations and is set up for exchanging signals with an electrical module of the objective lens or an external unit.
    Type: Application
    Filed: July 21, 2019
    Publication date: January 23, 2020
    Inventors: Jochen Franke, Joachim Welker
  • Publication number: 20200029001
    Abstract: A lens main body includes an inner housing, a lens element mounted on the inner housing, an adjustable functional element mounted on the inner housing, and an electrical drive arranged on the inner housing to adjust the functional element, a controller arranged on the inner housing, a securing device configured to reversibly receive an outer housing extending around the inner housing in a tubular fashion, and a first signal interface to receive control signals for the controller, arranged on the inner housing, and configured to reversibly couple to a mating interface of the outer housing. An outer housing for the lens main body, and a lens formed from the lens main body and the outer housing have an altered functional scope vis-à-vis the lens main body. In addition, a lens assembly includes, besides the lens main body, two outer housings having a different functional scope.
    Type: Application
    Filed: July 20, 2019
    Publication date: January 23, 2020
    Inventors: Jochen Franke, Christophe Casenave
  • Publication number: 20190287277
    Abstract: A method for establishing and/or reducing artifacts that arise when reconstructing (R) an MPI overall image data record from MPI signal data and an appended system matrix (SMapp(r,f)), wherein the appended system matrix (SMapp(r,f)) includes system matrices of different particle classes (P1, P2). The method includes setting a selection region (cvn(r)) of a reconstructed MPI overall image data record (cn(r)),producing virtual signal data (sn(f)) by inverse transformation of the selection region, reconstructing a virtual overall image data record (c?vn(r)) from the virtual signal data and the appended system matrix, setting an artifact region (cartifact_n(r)) within the reconstructed virtual overall image data record so that the artifact region has only voxels lying outside of the selection region, and assigning the image data present in the artifact region as artifact image data (Cartifact_n(r)). This permits ghost artifacts to be corrected.
    Type: Application
    Filed: March 13, 2019
    Publication date: September 19, 2019
    Inventors: Jochen FRANKE, Michael HERBST
  • Publication number: 20190285710
    Abstract: A method for establishing a local concentration distribution of magnetic particles of at least one particle class within an examination volume or a variable derived from this concentration distribution. The method includes providing at least one system matrix, providing MPI signal data of at least one sample including magnetic particles of at least one particle class within a measurement volume, and reconstructing spatially resolved MPI image data from the provided MPI signal data. At least one spatial projection of at least one part of the system matrix is carried out along a projection direction and a projected system matrix is generated thereby. The reconstruction of the MPI image data is implemented with the at least partly projected system matrix, as a result of which MPI image data of a spatial projection of the local concentration distribution of the magnetic particles are produced along the projection direction.
    Type: Application
    Filed: March 13, 2019
    Publication date: September 19, 2019
    Inventors: Jochen FRANKE, Michael HERBST
  • Patent number: 10378891
    Abstract: A system for measuring the displacement of a surface in a material handling system relative to a base reference is provided. The system includes scanning means to generate point cloud data of the surface relative to a reference point to define a three-dimensional image of the surface, storage means to store base reference data in respect of the base reference, and processing means to process the point cloud data and the base reference data to determine the relative displacement of the surface with respect to the base reference. The processing means includes a referencing means to orientate the point cloud data relative to key reference data of the base surface and transforming the point cloud data and the base reference data into a common co-ordinate system, and displacement processing means to calculate the displacement between the surface and the base reference using both sets of data in the co-ordinate system.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: August 13, 2019
    Assignee: Outotec Pty Ltd
    Inventors: Jochen Franke, Michael Paul Stewart, Derek Lichti
  • Patent number: 10215826
    Abstract: An MPI-apparatus comprising a magnet system for generating a time-varying and position-dependent magnetic field and a detection system detecting signals from MPI contrast agents exposed to said magnetic field within a detection volume, said signals being suitable for reconstructing an image of the spatial and temporal distribution of said MPI contrast agents, is characterized in that the magnet system comprises an array with a plurality of permanent magnetic elements geometrically arranged in such a way that at least a part of the plurality of permanent magnetic elements are moved with sufficient speed in the vicinity of the detection volume to create the spatial and temporal magnetic field variations for inducing within the contrast agent the MPI signals recorded by the detection system. This avoids the high power requirements of current MPI scanners, while opening the way for higher spatial resolutions and variable scanning frequencies.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: February 26, 2019
    Assignee: Bruker BioSpin MRI GmbH
    Inventors: Ulrich Heinen, Jochen Franke
  • Patent number: 10191130
    Abstract: A device for alternating examination of a measurement object (170) by means of MPI and MRI with two magnetic field-generating elements is presented. The device is characterized by a main magnet coil system with two coaxial partial coil systems (100a1, 100a2; 100b2, 100b1) arranged mirror-symmetrically relative to a central plane running perpendicularly to the z-axis through the first volume under investigation (162). The volumes under investigation are superimposed. A polarity reversal device (190) reverses the polarity of the current through a partial coil system and the main magnet coil system generates a homogeneous magnetic field of at least sixth order in the first volume under investigation when the partial coil systems have identical polarity, and a spatially strongly varying magnetic field profile in the second volume under investigation when the polarities are opposite. Repositioning of the measurement object is thereby simplified or can even be eliminated.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: January 29, 2019
    Assignee: BRUKER BIOSPIN MRI GMBH
    Inventors: Michael Heidenreich, Jochen Franke, Volker Niemann, Rainer Pietig
  • Patent number: 10172587
    Abstract: A phantom system has a housing (2) with a lower part (3) having an opening in the z-direction and a cover part (4) for closing the opening of the housing (2). A first plate-shaped insert element (10a) has at least one depression (11a) for receiving a liquid substance. The lower part (3) and the cover part (4) delimit a cavity (5) with an insert area (8), which is constituted to receive the first insert element (10a). A first sealing element (14a) seals the first insert element (10a) against the cavity (5) and a fixing facility fixes the first insert element (10a) in the cavity (4) of the housing (2) in an operating state of the MPI phantom. The phantom permits good contrast in MPI, MRI, or ?CT using liquid contrast media.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: January 8, 2019
    Assignee: Bruker BioSpin MRI GmbH
    Inventors: Jochen Franke, Ulrich Heinen
  • Publication number: 20180128598
    Abstract: A system for orientating point cloud data of a first surface relative to base reference data of a structure includes an input source generator adapted to provide the point cloud data, a tilt-correction means for orientating the point cloud data relative to the base reference data, a data editing means to filter spurious point data from the point cloud data, and a volume measurement means to measure the volume of objects that are non-fixably connected to the surface to segment the non-fixably connected objects from the point cloud data. The first surface is the surface of a wear liner. After orientation of the point cloud data with the base reference data, the surface displacement of the first surface to a second surface of the base reference substantially distinct from the first surface can be calculated to identify the thickness of the wear liner.
    Type: Application
    Filed: March 14, 2017
    Publication date: May 10, 2018
    Inventors: Michael Paul Stewart, Derek Lichti, Jochen Franke
  • Patent number: 9927500
    Abstract: Device for alternating examination of a measurement object (103) by means of MPI and MRI within a magnetic system is characterized in that the magnetic system has a specified magnetic field profile, which is not temporally variable during the alternating examination, and both magnetic field generating elements (101,102; 201,202; 801a,801b,811,812) generate a magnetic field portion, in the first examination region (104) and in the second examination region (105), which is essential for the MRI operation and for the MPI operation, and in that there is a transport apparatus (106) by means of which the measurement object can be moved out of the first examination region and into the second examination region and/or vice versa. The total space requirement for both modalities is thus reduced and the complexity of an integrally designed hybrid system is minimized.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: March 27, 2018
    Assignee: Bruker BioSpin MRI GmbH
    Inventors: Michael Heidenreich, Jochen Franke, Volker Niemann, Rainer Pietig
  • Patent number: 9829308
    Abstract: A method for measuring the displacement of a surface relative to a base reference. The method includes generating point cloud data between a reference point and a surface disposed distally from the reference point to define a three dimensional image of the surface. The method also includes determining the location and direction of key reference parameters of the object defined by the three dimensional image from the point cloud data. The method also includes obtaining base reference data in a prescribed co-ordinate system in respect of a base reference relative to the surface. Further, the method provides for processing the point cloud data and the base reference data, orientating the point cloud data relative to the key reference parameters defined by the base reference data and transforming the point cloud data into a co-ordinate system coinciding with the base reference data.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: November 28, 2017
    Assignee: OUTOTEC PTY LTD
    Inventors: Michael Paul Stewart, Derek Lichti, Jochen Franke
  • Publication number: 20170276473
    Abstract: A system for orientating point cloud data of a first surface relative to base reference data of a structure includes an input source generator adapted to provide the point cloud data, a tilt-correction means for orientating the point cloud data relative to the base reference data, a data editing means to filter spurious point data from the point cloud data, and a volume measurement means to measure the volume of objects that are non-fixably connected to the surface to segment the non-fixably connected objects from the point cloud data. The first surface is the surface of a wear liner. After orientation of the point cloud data with the base reference data, the surface displacement of the first surface to a second surface of the base reference substantially distinct from the first surface can be calculated to identify the thickness of the wear liner.
    Type: Application
    Filed: March 14, 2017
    Publication date: September 28, 2017
    Inventors: Michael Paul Stewart, Derek Lichti, Jochen Franke
  • Patent number: 9625253
    Abstract: A system for orientating scan cloud data of a surface relative to base reference data is provided. The orientating system includes an input source generator adapted to provide the scan cloud data, a tilt-correction means for orientating the point cloud data relative to the base reference data, and a data editing means for filtering spurious point data from the accumulated point cloud data, wherein the base reference data represents at least geometrical parameters of a base reference, the base reference being substantially distinct from the target surface. A system for identifying features in scan could data of a surface is also provided. The identifying system includes an input source generator adapted to provide the scan cloud data, and a partitioning means for partitioning the point cloud data into discrete segments corresponding to different geometric sections of the surface.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: April 18, 2017
    Inventors: Michael Paul Stewart, Derek Lichti, Jochen Franke
  • Publication number: 20160278735
    Abstract: A phantom system has a housing (2) with a lower part (3) having an opening in the z-direction and a cover part (4) for closing the opening of the housing (2). A first plate-shaped insert element (10a) has at least one depression (11a) for receiving a liquid substance. The lower part (3) and the cover part (4) delimit a cavity (5) with an insert area (8), which is constituted to receive the first insert element (10a). A first sealing element (14a) seals the first insert element (10a) against the cavity (5) and a fixing facility fixes the first insert element (10a) in the cavity (4) of the housing (2) in an operating state of the MPI phantom. The phantom permits good contrast in MPI, MRI, or ?CT using liquid contrast media.
    Type: Application
    Filed: March 15, 2016
    Publication date: September 29, 2016
    Inventors: Jochen Franke, Ulrich Heinen
  • Publication number: 20160216353
    Abstract: An MPI-apparatus comprising a magnet system for generating a time-varying and position-dependent magnetic field and a detection system detecting signals from MPI contrast agents exposed to said magnetic field within a detection volume, said signals being suitable for reconstructing an image of the spatial and temporal distribution of said MPI contrast agents, is characterized in that the magnet system comprises an array with a plurality of permanent magnetic elements geometrically arranged in such a way that at least a part of the plurality of permanent magnetic elements are moved with sufficient speed in the vicinity of the detection volume to create the spatial and temporal magnetic field variations for inducing within the contrast agent the MPI signals recorded by the detection system. This avoids the high power requirements of current MPI scanners, while opening the way for higher spatial resolutions and variable scanning frequencies.
    Type: Application
    Filed: January 19, 2016
    Publication date: July 28, 2016
    Inventors: Ulrich Heinen, Jochen Franke
  • Publication number: 20150316628
    Abstract: A device for alternating examination of a measurement object (170) by means of MPI and MRI with two magnetic field-generating elements is presented. The device is characterized by a main magnet coil system with two coaxial partial coil systems (100a1, 100a2; 100b2, 100b1) arranged mirror-symmetrically relative to a central plane running perpendicularly to the z-axis through the first volume under investigation (162). The volumes under investigation are superimposed. A polarity reversal device (190) reverses the polarity of the current through a partial coil system and the main magnet coil system generates a homogeneous magnetic field of at least sixth order in the first volume under investigation when the partial coil systems have identical polarity, and a spatially strongly varying magnetic field profile in the second volume under investigation when the polarities are opposite. Repositioning of the measurement object is thereby simplified or can even be eliminated.
    Type: Application
    Filed: November 22, 2013
    Publication date: November 5, 2015
    Inventors: Michael Heidenreich, Jochen Franke, Volker Niemann, Rainer Pietig
  • Publication number: 20150285875
    Abstract: Device for alternating examination of a measurement object (103) by means of MPI and MRI within a magnetic system is characterized in that the magnetic system has a specified magnetic field profile, which is not temporally variable during the alternating examination, and both magnetic field generating elements (101,102; 201,202; 801a,801b,811,812) generate a magnetic field portion, in the first examination region (104) and in the second examination region (105), which is essential for the MRI operation and for the MPI operation, and in that there is a transport apparatus (106) by means of which the measurement object can be moved out of the first examination region and into the second examination region and/or vice versa. The total space requirement for both modalities is thus reduced and the complexity of an integrally designed hybrid system is minimized.
    Type: Application
    Filed: August 16, 2013
    Publication date: October 8, 2015
    Inventors: Michael Heidenreich, Jochen Franke, Volker Niemann, Rainer Pietig