Patents by Inventor Joerg Stuerzebecher

Joerg Stuerzebecher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Base-substituted benzylamine analogs for use as coagulation factor xa inhibitors, the production and use thereof
    Publication number: 20070066539
    Abstract: The invention relates to the novel base-substituted benzylamine analogs of general formula (I), wherein A represents P2-P1 with P1=(A) and P2=(B), for use as coagulation factor Xa inhibitors. The invention also relates to the production and use of said analogs in the therapy and prophylaxis of cardiovascular diseases and thromboembolic events.
    Type: Application
    Filed: September 13, 2004
    Publication date: March 22, 2007
    Inventors: Jörg Stürzebecher, Torsten Steinmetzer, Andrea Schweinitz, Anne Sturzebecher, Daniel Donnecke
  • Selective inhibitors of the urokinase plasminogen activator
    Patent number: 7049460
    Abstract: The present invention relates to novel selective inhibitors of the urokinase plasminogene activator (uPA, EC 3.4.21.31) of the aryl guanidine type.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: May 23, 2006
    Assignee: Wilex AG
    Inventors: Viktor Magdolen, Luis Moroder, Stefan Sperl, Jörg Stürzebecher, Olaf Wilhelm
  • Highly selective inhibitors of the urokinase plasminogen activator
    Patent number: 7049344
    Abstract: A method is described for inhibiting urokinase plasminogen activator in a human or animal patient.
    Type: Grant
    Filed: November 22, 2004
    Date of Patent: May 23, 2006
    Assignees: Wilex Biotechnology GmbH, Max-Planck-Gessellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Viktor Magdolen, Stefan Sperl, Joerg Stuerzebecher, Olaf Wilhelm, Nuria Arroyo De Prada, Luis Moroder, Robert Huber, Uwe Jacob, Wolfram Bode
  • Arginine mimetics as factor Xinhibitors
    Patent number: 7038074
    Abstract: The invention relates generally to a novel type of arginine mimetics which are inhibitors of factor Xa; to pharmaceutical compositions which comprise these mimetics; and to the use of these arginine mimetics for producing compositions for antithrombotic therapy.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: May 2, 2006
    Assignee: Wilex AG
    Inventors: Luis Moroder, Stefan Sperl, Jörg Stürzebecher
  • Highly selective inhibitors of the urokinase plasminogen activator
    Publication number: 20050119348
    Abstract: A method is described for inhibiting urokinase plasminogen activator in a human or animal patient.
    Type: Application
    Filed: November 22, 2004
    Publication date: June 2, 2005
    Inventors: Viktor Magdolen, Stefan Sperl, Joerg Stuerzebecher, Olaf Wilhelm, Nuria Arroyo De Prada, Luis Moroder, Robert Huber, Uwe Jacob, Wolfram Bode
  • Inhibitors for the blood-clotting factor Xa
    Patent number: 6841701
    Abstract: The invention relates to derivatives of amidino-benzylamine, especially derivatives of 4-amidino-benzylamine, with two bonded amino acids. These derivatives represent a novel group of highly active and very selective F Xa-inhibitors for treating cardiovascular diseases and thrombotic events.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: January 11, 2005
    Assignee: Curacyte AG
    Inventors: Jörg Stürzebecher, Torsten Steinmetzer, Sebastian Künzel, Andrea Schweinitz
  • Highly selective inhibitors of the urokinase plasminogen activator
    Patent number: 6841702
    Abstract: The invention relates to novel selective inhibitors of the urokinase plasminogen activator (uPA, EC 3.4.21.31), of the arylguanidine type.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: January 11, 2005
    Assignees: Wilex Biotechnology GmbH, Max-Planck-Gesellschaft zur Forderung der Wissenschaften EV
    Inventors: Viktor Magdolen, Stefan Sperl, Joerg Stuerzebecher, Olaf Wilhelm, Nuria Arroyo De Prada, Luis Moroder, Robert Huber, Uwe Jacob, Wolfram Bode
  • Urokinase inhibitors
    Patent number: 6831196
    Abstract: The invention relates to a highly active, highly specific urokinase inhibitor which is suitable for therapeutic applications and can be synthesized in an extremely simple manner. Surprisingly, it was found that amidino benzylamine derivatives, especially 4-amidino-benzylamine, with two bonded amino acids represent a new group of highly active and very selective uPA inhibitors. The urokinase inhibitors can be used in medical applications, e.g. in the treatment of malign tumors such as in cases of metastatic spread.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: December 14, 2004
    Assignee: Curacyte AG
    Inventors: Jörg Stürzebecher, Torsten Steinmetzer, Andrea Schweinitz
  • Urokinase inhibitors
    Patent number: 6680320
    Abstract: The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: January 20, 2004
    Assignee: Wilex AG
    Inventors: Olaf Wilhelm, Viktor Magdolen, Jörg Stürzebecher, John Foekens, Verena Lutz
  • Urokinase inhibitors
    Patent number: 6624169
    Abstract: The invention relates to the use of derivatives of 3-amidinophenylalanine as urokinase inhibitors for treating malignant tumors and the formation of metastases.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: September 23, 2003
    Assignee: Wilex Biotechnology GmbH
    Inventors: Olaf Wilhelm, Viktor Magdolen, Jörg Stürzebecher, John Foekens, Verena Lutz
  • Highly selective inhibitors of the urokinase plasminogen activator
    Publication number: 20030100584
    Abstract: The invention relates to novel selective inhibitors of the urokinase plasminogen activator (uPA, EC 3.4.21.31), of the arylguanidine type.
    Type: Application
    Filed: September 20, 2002
    Publication date: May 29, 2003
    Inventors: Viktor Magdolen, Stefan Speri, Joerg Stuerzebecher, Olaf Wilhelm, Nuria Arroyo De Prada, Luis Moroder, Robert Huber, Uwe Jacob, Wolfram Bode
  • Piperazides of substituted phenylalanine derivatives as thrombin inhibitors
    Patent number: 5607937
    Abstract: The present invention relates to D,L-, L- and D-phenylalanine piperazides of formula (I) defined in claim 1 that inhibit blood coagulation, and thrombin and/or trypsin, respectively. The compounds are extraordinarily absorbable after oral, intraduodenal and in particular rectal administration and show only a low toxicity.
    Type: Grant
    Filed: January 5, 1995
    Date of Patent: March 4, 1997
    Assignee: Pentapharm AG
    Inventors: Joerg Stuerzebecher, Helmut Vieweg, Peter Wikstroem, Christoph Adler