Publication number: 20170240556
Abstract: The invention relates to a compound of the general formula (I) or a physiologically functional derivative, solvate or salt thereof, wherein A is a bond, alkyl or alkoxy optionally substituted with one or more R? as defined herein, *—N(R??)CO—, *—CON(R??)—, *—N(R??)CON(R??)—, —S—, —SO—, *—N(R??)—, *—N(R??)CO—, *—CON(R??)—, —CO—, *—COO—, *—OOC—, *—SO2N(R??)—, —SO2, or *—N(R??)—SO2—, wherein R?? is as defined herein and * specifies the point of attachment to X; X is aryl, cycloalkyl, aralkyl, heterocyclyl or heteroaryl, which may be substituted with one or more RX further described herein; L is a bond or *—N(RN)CO—, *—CON(RN)—, *—N(RN)—, *—C?N(RN)—, *—N(RN)-alkyl-, *-alkyl-N(RN)—, *—N(RN)CON(RN)—, *—CO—, *—CO2—, alkyl, *-alkyl-O-alkyl-, *—NCO—CH?CH—, *—CH?CH—CONH—, *—SO2N(RN)—, *—N(RN)SO2—, or heterocyclyl, wherein * specifies the point of attachment to X; Y is H, alkyl, aryl, aralkyl, cycloalkyl, heterocyclyl or heteroaryl, which may be substituted with one or more RY further described herein; and R and RN
Type:
Application
Filed:
February 27, 2017
Publication date:
August 24, 2017
Applicant:
4SC DISCOVERY GMBH
Inventors:
Johann LEBAN, Mirko ZAJA
