Patents by Inventor Johannes Frohlich

Johannes Frohlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel derivatives of 4a,5,9,10,11,12-hexahydrobenzofuro[3a,3,2][2]-benzazepine, method for the production thereof and use thereof in the production of medicaments
    Publication number: 20070105837
    Abstract: The invention relates to novel derivatives of 4a,5,9,10,11,12-hexahydro-benzofuro[3a,3,2] [2]benzazepine of general formulae 1a, 1b and 1c. Compounds 1a, 1b and 1c can be produced in an efficient manner on an industrial scale with the desired optical purity and are suitable for the production of medicaments for the treatment of a diverse range of symptoms, particularly diseases of the central nervous system (CNS), on account of the pharmacological effect thereof.
    Type: Application
    Filed: September 9, 2004
    Publication date: May 10, 2007
    Inventors: Laszlo Czollner, Beate Kalz, Stefan Welzig, J. Frantsits, Ulrich Jordis, Johannes Frohlich
  • Derivatives and analogs of galanthamine
    Publication number: 20070027138
    Abstract: New compounds of general formula I
    Type: Application
    Filed: June 28, 2006
    Publication date: February 1, 2007
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kalz, Stefan Welzig
  • Derivatives and analogs of galanthamine
    Patent number: 7166588
    Abstract: New compounds of general formula I
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: January 23, 2007
    Assignee: Sanochemia Pharmazeutika Aktiengesellschaft
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kälz, Stefan Welzig
  • Benzazepine derivatives, drugs containing these and use of the same for producing drugs
    Patent number: 7101890
    Abstract: New derivatives of benzazepine, particularly of benzofuro[3a,3,2,ef][2]benzazepin of the general formula (I) and new compounds of the general formula (III) Drugs, containing compounds of formulas (I) and/or (III), which can be used successfully for the treatment of Alzheimer's disease and related dementia conditions, as well as for the treatment of Langdon-Down syndrome, are also described.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: September 5, 2006
    Assignee: Sanochemia Ltd.
    Inventors: Laszlo Czollner, Johannes Frohlich, Ulrich Jordis, Bernhard Kuenburg
  • Methods for producing norgalanthamine, as well as isomers, salts and hydrates thereof
    Publication number: 20060069251
    Abstract: The invention relates to processes, which can be performed on an industrial scale, for the production of norgalanthamine, norgalanthamine derivatives and isomers thereof of general formula (A) as well as salts or hydrates thereof with general formula (B). As processes for the production of compounds with general formula (A) or (B), an oxidative demethylation and a catalytic demethylation of the corresponding galanthamine compounds are indicated.
    Type: Application
    Filed: January 9, 2003
    Publication date: March 30, 2006
    Inventors: Ulrich Jordis, Matthias Treu, Manfred Hirnschall, Johannes Frohlich, Laszlo Crollner, Beate Kalz, Thomas Kalz, Peter Kuhnhackl
  • New benzazepine derivatives, drugs containing these and use of the same for producing drugs
    Publication number: 20040067974
    Abstract: New derivatives of benzazepine, particularly of benzofuro[3a,3,2,ef][2]benzazepin of the general formula (I) 1
    Type: Application
    Filed: August 26, 2003
    Publication date: April 8, 2004
    Applicant: SANOCHEMIA LTD.
    Inventors: Laszlo Czollner, Johannes Frohlich, Ulrich Jordis, Bernhard Kuenburg
  • Benzazepine derivatives, medicaments containing the same and their use to prepare medicaments
    Patent number: 6638925
    Abstract: New derivatives of benzazepine, particularly of benzofuro[3a,3,2,ef][2]benzazepin of the general formula (I) and new compounds of the general formula (III) Drugs, containing compounds of formulas (I) and/or (III), which can be used successfully for the treatment of Alzheimer's disease and related dementia conditions, as well as for the treatment of Langdon-Down syndrome, are also described.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: October 28, 2003
    Assignee: Sanochemia Ltd.
    Inventors: Laszlo Czollner, Johannes Frohlich, Ulrich Jordis, Bernhard Kuenburg
  • Novel derivatives and analogues of galanthamin
    Publication number: 20030199493
    Abstract: New compounds of general formula I 1
    Type: Application
    Filed: March 18, 2002
    Publication date: October 23, 2003
    Inventors: Ulrich Jordis, Johannes Frohlich, Matthias Treu, Manfred Hirnschall, Laszlo Czollner, Beate Kalz, Stefan Welzig
  • BENZAZEPINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME AND THEIR USE TO PREPARE MEDICAMENTS
    Publication number: 20030092700
    Abstract: New derivatives of benzazepine, particularly of benzofuro[3a,3,2,ef][2]benzazepin of the general formula (I) 1
    Type: Application
    Filed: February 11, 1999
    Publication date: May 15, 2003
    Inventors: LASZLO CZOLLNER, JOHANNES FROHLICH, ULRICH JORDIS, BERNHARD KUENBURG
  • Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine
    Patent number: 6407229
    Abstract: The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: June 18, 2002
    Assignee: Sanochemia Pharmazeutika AG
    Inventors: Laszlo Czollner, Johannes Fröhlich, Ulrich Jordis, Bernhard Küenburg
  • Processes for the preparation of derivatives of 4a, 5, 9, 10, 11, 12-hexahydro-6H-benzofuro-[3a, 3, 2-ef][2]benzazepine
    Patent number: 6369238
    Abstract: The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a, 5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: April 9, 2002
    Assignee: Sanochemia Pharmazeutica
    Inventors: Laszlo Czollner, Johannes Fröhlich, Ulrich Jordis, Bernhard Küenburg
  • Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2]benzazepine
    Patent number: 6043359
    Abstract: The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: March 28, 2000
    Assignee: Sanochemia Pharmazeutica Aktiengesellschaft
    Inventors: Laszlo Czollner, Johannes Frohlich, Ulrich Jordis, Bernhard Kuenburg