Abstract: Systems and methods for model evaluation. A protected class model that satisfies an accuracy threshold is built by using: data sets for use by a modeling system being evaluated, and protected class membership information for each data set. A target for the protected class model is a protected class membership variable indicating membership in a protected class. Each predictor of the protected class model is a predictor of an evaluated model used by the modeling system. A target of the evaluated model is different from the target of the protected class model. Each predictor is a set of one or more variables of the data sets. For each predictor of the protected class model, a protected class model impact ranking value and a modeling system impact ranking value are determined.

Abstract: A fuel tank comprises an interior wall, a sump, and a baffle that comprises a center fitting, a full-length containment petal, a partial-length containment petal, a dump tube. The full-length containment petal comprises a full-length side edge, extending radially outward from the center fitting. The partial-length containment petal comprises a partial-length side edge, extending radially outward from the center fitting. The dump tube is connected to the sump. The full-length side edge of the full-length containment petal is longer than the partial-length side edge of the partial-length containment petal. All of the partial-length side edge of the partial-length containment petal is attached to a linear portion of the full-length side edge of the full-length containment petal.

Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: Selectively masking data in messages is provided. A masking expression is retrieved from a schema. The masking expression corresponds to a particular attribute within related messages generated by a producer application and sent to an immutable datastore for consumption by a consumer application of the computer that is registered to receive the messages related to a particular topic from the immutable datastore. A particular attribute value is masked only in those messages received from the immutable datastore that contain the particular attribute value during a time period when the particular attribute value is associated with the masking expression.

Abstract: An inertial point-source matter-wave atom interferometer gyroscope includes an analyzer that receives fringe images of gyroscope atoms and includes: a first fringe image that includes a first fringe phase, a second fringe image that includes a second fringe phase; and a third fringe image that includes a third fringe phase, wherein the first fringe phase, the second fringe phase, and the third fringe phase are different; a phase mapper of the analyzer that produces a interferometric phase map for the gyroscope atoms from the fringe images of the gyroscope atoms; and a fitter of the analyzer in communication with the phase mapper and that receives the interferometric phase map from the analyzer and determines inertial parameters of the gyroscope atoms from the interferometric phase map, the inertial parameters including an acceleration and a rotation rate of the inertial point-source matter-wave atom interferometer gyroscope relative to the gyroscope atoms.

Abstract: A central database system provides predictive web navigation using machine learning and clustering to guide a user to a web page. After tracking a number of web pages viewed by various users on one or more web domains and the orders in which these web pages are viewed, the central database system can train a model to predict which web page a user is likely to view next. If the user is lost while navigating, the central database system may guide the user to the predicted web page. In one example of guidance, the central database system presents a web element with a hyperlink to the predicted web page. For example, the central database system can modify a web page that the lost user is presently viewing to include an iframe with a recommendation to travel to a different web page.

Abstract: According to embodiments, a coated pharmaceutical container may include a pharmaceutical container comprising an interior surface and an exterior surface, wherein the pharmaceutical container may include a glass composition that has Class HGA1 hydrolytic resistance when tested according to the ISO 720 testing standard. The coated pharmaceutical container may further include a coating bonded to at least a portion of the exterior surface but not on any portion of the interior surface. The coating may have a coefficient of friction less than or equal to 0.7, and the coated pharmaceutical container may be thermally stable after heating at a temperature of at least 260° C. for a time period of 30 minutes.

Abstract: The invention provides a method of treating a tumor in a human patient comprising (i) identifying a patient as having a LAG-3 positive tumor and (ii) administering to the patient a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor, or an anti-CTLA4 antibody. In some embodiments, the method further comprises identifying the patient as having a LAG-3 positive PD-L1 positive tumor. In some embodiments, the LAG-3 inhibitor is an anti-LAG-3 antibody and the PD-1 pathway inhibitor is an anti-PD-1 antibody. The methods of the invention can improve response rates to treatment with a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, or a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor.

Abstract: An Augmented Reality (AR) wayfinder tracks the current location of a user within an indoor location relative to a path defined through the indoor location for the user. The path is broken into segments, each segment is a straight line between two nodes, and each node represents either a starting point in the path, a turn along the path, or an ending point in the path. As the user traverses the path, a remaining distance between the user device and the next node in the path is calculated. An AR object with attributes that correlate to the remaining distance to the next node is blended into and superimposed into a video that the user is viewing through the user device of the physical environment as the user travels along the path.

Abstract: A method and device for handling supports which support biological cell cultures or auxiliary agents for treatment of biological cell cultures, using one or more modules, at least one of which is a handling device. Each one of a plurality of supports rests with its edges on support elements, and, depending on the type of supports or the type of auxiliary means supported thereby, the supports require different storage heights, some of which are greater than one or more times a standardized vertical spacing of the support elements. The supports have an information carrier, the information of which can be read by a reading device and can be evaluated by a computing device. For optimal use of the compartments of the storage device, the information contains details about the storage height of the support in question and the handling of the supports is performed using these details.

Abstract: A mousepad designed to enable privacy when the user of a laptop computer, tablet computer, desk top computer, or cellphone does not want to be seen. The mouse pad acts as a regular mouse pad whereas the detachable clip is securely fastened on whatever device is being used with the intent of covering the camera. The markings on the detachable clip clearly display a microphone and question mark which are used as a reminder to mute the microphone on the laptop computer, tablet computer, desk top computer, or cellphone.

Abstract: A method for activating a catalyst is described comprising the steps of: (i) installing a reduced and passivated catalyst containing crystallites of a catalytic metal comprising nickel, cobalt or iron in elemental form encapsulated by a layer comprising an oxide of the catalytic metal in a reactor, such as a steam methane reforming reactor, in which it is to be used, and (ii) heating the reduced and passivated catalyst in the reactor under a vacuum or an inert gas to a temperature in the range (TT?X) to (TT+Y), where TT is the Tammann temperature of the catalytic metal in elemental form in degrees Centigrade, X is 400 and Y is 200, to form a catalytically active surface on the catalyst without requiring the application of a reducing gas.

Abstract: Systems and methods for matching content elements to surfaces in a spatially organized 3D environment. The method includes receiving content, identifying one or more elements in the content, determining one or more surfaces, matching the one or more elements to the one or more surfaces, and displaying the one or more elements as virtual content onto the one or more surfaces.

Abstract: Multi-User Multiple Input, Multiple Output (MU-MIMO) data transmissions are provided with a forward-predictive precoding matrix to mitigate the effects of a change in a state of a communication channel. First and second soundings are performed, at first and second times, to a receive antenna over a channel and, responsive to each of the soundings, first and second Channel State Information (CSI) are received. Based on the first and second CSI, a change in a state of the channel over a time period between the first and second time is determined. Based on the change in the state of the channel, a forward-predictive channel state matrix and/or a forward-predictive precoding matrix are determined that reflect a state of the channel at a future time and that are consistent with the determined change in the state over the time period. The forward-predictive precoding matrix is applied to a data transmission.

Abstract: An air interface plane (AIP) of a radio frequency (RF) aperture includes: a circuit board having a first side and a second side opposite the first side; and a matrix of tapered elements arranged on the first side of the circuit board and secured to the circuit board, the matrix of tapered elements cooperating to at least one of receive or transmit an over-the-air RF signal. Suitably, each tapered element of the matrix has: a central hub extending along a longitudinal axis from a hub base which is proximate to the first side of the circuit board to an apex of the tapered element which is distal from the first side of the first circuit board; and a plurality of arms extending from the central hub at the apex of the tapered element, each of the plurality of arms including a first portion that projects the arm radially away from the longitudinal axis and a second portion that projects the arm longitudinally toward the first side of the circuit board.

Abstract: A central database system provides predictive web navigation using machine learning and clustering to guide a user to a web page. After tracking a number of web pages viewed by various users on one or more web domains and the orders in which these web pages are viewed, the central database system can train a model to predict which web page a user is likely to view next. If the user is lost while navigating, the central database system may guide the user to the predicted web page. In one example of guidance, the central database system presents a web element with a hyperlink to the predicted web page. For example, the central database system can modify a web page that the lost user is presently viewing to include an iframe with a recommendation to travel to a different web page.

Abstract: Apparatus for generating a supply of air at positive pressure for the amelioration or treatment of a respiratory disorder includes a first chamber, a second chamber, at least one inlet tube structured and configured to allow ambient air to enter the first chamber, at least one flow tube structured and configured to allow air to pass from the first chamber to the second chamber, and a blower structured and configured to produce a flow of air at positive pressure. The blower is positioned in the first chamber and structured and configured to receive air from the second chamber. The blower includes a housing structured and configured to sealingly separate air flow through an interior of the housing from the first chamber. The at least one inlet tube is axially spaced from the at least one flow tube.

Abstract: A communication exchange between two wireless communication devices is monitored. A communication device configured to function as a Sniffer device synchronizes the communication device to a frequency and a timing employed between the two wireless communication devices on a main wireless communication channel. The wireless communication exchanges are monitored, in which the wireless communication exchanges are packet-based data exchanges or tone-based data exchanges. The operations for wireless communication exchanges are repeated across a plurality of different frequencies. The communication device then combines a plurality of phase and/or magnitude measurements and determines a value of phase and/or magnitude error introduced by each device based on the combined plurality of phase and/or magnitude measurements.

Abstract: Disclosed herein are catheters having multiple coil layers, and associated systems and methods. In some embodiments, a catheter includes an inner liner, a plurality of wires over the inner liner, and an outer sheath over the wires. The wires are coiled about a longitudinal axis of the catheter in a first direction to form a first coil layer over the inner liner, and the wires are coiled about the longitudinal axis in a second direction, opposite the first direction, over the first coil layer to form a second coil layer over the first coil layer. The wires each include a continuous/self-terminating end portion wherein the wire switches from the first direction to the second direction and transitions from the inner coil layer to the outer coil layer.

Abstract: Methods and apparatus relating to predicting outcome in a sporting environment are described. The methods and apparatus are used to relate trajectory performance of an object to body motions and body orientation associated with a generating the trajectory of the object. When equipment is utilized to generate the trajectory of an object, than the effects of equipment motions and equipment orientation can be also related to trajectory performance. The method and apparatus can be used to predict body motions and body orientations that increase the likelihood of achieving a desired outcome including specifying optimum motions and orientations for a particular individual. The method and apparatus may be used in training, coaching and broadcasting environments.