Patents by Inventor John Cashman

John Cashman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9403800
    Abstract: Methods and small molecule compounds for inhibition of cancer cell proliferation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, E, F, G, I, J, R, R1, R2, R2?, R3, R4, R5, R6, R7, R8, R9 are as described herein.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: August 2, 2016
    Assignee: ChemRegen, Inc.
    Inventors: John Cashman, Mark Mercola, Dennis Schade, Masanao Tsuda
  • Patent number: 9233926
    Abstract: Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: or a chirally pure stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: January 12, 2016
    Assignees: Sanford-Burnham Medical Research Institute, Human Biomolecular Research Institute, ChemRegen, Inc.
    Inventors: Mark Mercola, John Cashman, Marion Lanier, Erik Willems, Dennis Schade
  • Patent number: 9023340
    Abstract: Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the compound of Formula I and II: or a pharmaceutically acceptable salt or solvate thereof, wherein A, X, Q, R1, R2, R3, R4 are as described herein.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: May 5, 2015
    Assignee: ChemRegen, Inc.
    Inventors: John Cashman, Marion Lanier, Mark Mercola, Dennis Schade, Erik Willems
  • Patent number: 9012217
    Abstract: Methods and small molecule compounds for stem cell differentiation are provided.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: April 21, 2015
    Assignees: Burnham Institute for Medical Research, Human Biomolecular Research Institute
    Inventors: Mark Mercola, Marcia Dawson, John Cashman, Paul J. Bushway
  • Publication number: 20130190258
    Abstract: Methods and small molecule compounds for inhibition of cancer cell proliferation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, E, F, G, I, J, R, R1, R2, R2?, R3, R4, R5, R6, R7, R8, R9 are as described herein.
    Type: Application
    Filed: January 24, 2013
    Publication date: July 25, 2013
    Inventors: John CASHMAN, Mark MERCOLA, Dennis SCHADE, Masanao TSUDA
  • Publication number: 20130177535
    Abstract: Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the compound of Formula I and II: or a pharmaceutically acceptable salt or solvate thereof, wherein A, X, Q, R1, R2, R3, R4 are as described herein.
    Type: Application
    Filed: July 2, 2012
    Publication date: July 11, 2013
    Inventors: John Cashman, Marion Lanier, Mark Mercola, Dennis Schade, Erik Willems
  • Publication number: 20130157947
    Abstract: Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: or a chirally pure stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.
    Type: Application
    Filed: March 23, 2012
    Publication date: June 20, 2013
    Inventors: MARK MERCOLA, John Cashman, Marion Lanier, Erik Willems, Dennis Schade
  • Publication number: 20130123253
    Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.
    Type: Application
    Filed: May 1, 2012
    Publication date: May 16, 2013
    Applicant: HUMAN BIOMOLECULAR RESEARCH INSTITUTE
    Inventor: John CASHMAN
  • Patent number: 8168635
    Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: May 1, 2012
    Assignee: Human BioMolecular Research Institute
    Inventor: John Cashman
  • Publication number: 20110281356
    Abstract: Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 17, 2011
    Applicants: Human BioMolecular Research Institute, Sanford-Burnham Medical Research Institute
    Inventors: Mark Mercola, John Cashman, Marion Lanier, Erik Willems
  • Publication number: 20110264527
    Abstract: The present disclosure details apparatuses, methods, and systems for a code-mediated content delivery platform comprising a Graphical Code-Serving Interface and a Code Triggered Information Server (“GCSI/CTIS”). The GCSI/CTIS connects information encoding symbologies to graphical interface elements, thus expanding the useful information content and interactivity of graphical displays, advertisements, publications, broadcasts, and/or the like. GCSI/CTIS components facilitate wide ranging functionality, including generation of robust encoding symbologies, error-correction, media sampling and purchasing, social networking, and sales promotion programs.
    Type: Application
    Filed: June 23, 2011
    Publication date: October 27, 2011
    Inventors: Dudley Fitzpatrick, Jason Alan Snyder, Glenn Thomas, John Cashman, Ed Jordan, Devon Strawn
  • Publication number: 20100159596
    Abstract: Methods and small molecule compounds for stem cell differentiation are provided.
    Type: Application
    Filed: September 16, 2009
    Publication date: June 24, 2010
    Applicants: Burnham Institute for Medical Research, Human BioMolecular Research Institute
    Inventors: Mark Mercola, Marcia Dawson, John Cashman
  • Patent number: 7623637
    Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.
    Type: Grant
    Filed: January 2, 2007
    Date of Patent: November 24, 2009
    Assignee: ITXC IP Holdings S.a.r.l.
    Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
  • Publication number: 20080261967
    Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.
    Type: Application
    Filed: June 20, 2005
    Publication date: October 23, 2008
    Inventor: John Cashman
  • Publication number: 20070286846
    Abstract: This invention relates to a method for detoxication of inorganic or organic esters including OP nerve agents, cocaine, and respective analogs. More specifically, this invention pertains to the treatment of potentially neurotoxic esters or other ester groups by elaborating a more effective hydrolytic enzyme for therapeutic application. The structures of the synthesized OP analogs are provided. This invention also provides a diagnostic method and an Array Biosensor for detecting OP agents in biological and environmental samples.
    Type: Application
    Filed: June 4, 2007
    Publication date: December 13, 2007
    Inventors: John Cashman, Jun Zhang
  • Publication number: 20070165797
    Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.
    Type: Application
    Filed: January 2, 2007
    Publication date: July 19, 2007
    Applicant: ITXC IP Holdings S.a.r.I.
    Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
  • Patent number: 7167549
    Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: January 23, 2007
    Assignee: ITXC IP Holdings, S.a.r.l.
    Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
  • Patent number: 6455760
    Abstract: The present invention provides methods for using enhanced expression of nucleotide sequences encoding a flavin-containing monooxygenase (FMO) and suitable homologs thereof, to elicit desired traits, study biochemical pathways, and oxidize xenobiotics in plants.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: September 24, 2002
    Assignee: The Salk Institute of Biological Studies
    Inventors: Yunde Zhao, Joanne Chory, Christian Fankhauser, Detlef Weigel, John Cashman
  • Patent number: 6405975
    Abstract: A system for aiding ground maneuvering of an airplane. The system includes at least one camera mounted on the airplane for generating video images of at last one gear with tires, preferably a main or nose landing gear and the surrounding ground. The cockpit of the airplane includes a video display device that displays the generated video images and a user interface that allows selection of the format for displaying the generated video images. A camera mounted within a moveable component of the airplane is mounted on a movable device that compensates for component movement. The system also includes a display generator for generating in real-time superimposed oversteer targets on the displayed video images. The video images with oversteer targets assist the pilot in determining the airplane's actual position relative to runways, taxiways, obstacles and other ground features and to maneuver a plane with a wide wheel track long wheelbase, or both accordingly.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: June 18, 2002
    Assignee: The Boeing Company
    Inventors: Mithra M. K. V. Sankrithi, David W. McKenna, Mannon L. Wallace, Jr., Ronaldo O. Cabrera, Gary D. Reysa, Gerhard E. Seidel, John Yeeles, John Cashman