Patents by Inventor John Cashman
John Cashman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9403800Abstract: Methods and small molecule compounds for inhibition of cancer cell proliferation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, E, F, G, I, J, R, R1, R2, R2?, R3, R4, R5, R6, R7, R8, R9 are as described herein.Type: GrantFiled: January 24, 2013Date of Patent: August 2, 2016Assignee: ChemRegen, Inc.Inventors: John Cashman, Mark Mercola, Dennis Schade, Masanao Tsuda
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Patent number: 9233926Abstract: Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: or a chirally pure stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.Type: GrantFiled: March 23, 2012Date of Patent: January 12, 2016Assignees: Sanford-Burnham Medical Research Institute, Human Biomolecular Research Institute, ChemRegen, Inc.Inventors: Mark Mercola, John Cashman, Marion Lanier, Erik Willems, Dennis Schade
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Patent number: 9023340Abstract: Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the compound of Formula I and II: or a pharmaceutically acceptable salt or solvate thereof, wherein A, X, Q, R1, R2, R3, R4 are as described herein.Type: GrantFiled: July 2, 2012Date of Patent: May 5, 2015Assignee: ChemRegen, Inc.Inventors: John Cashman, Marion Lanier, Mark Mercola, Dennis Schade, Erik Willems
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Patent number: 9012217Abstract: Methods and small molecule compounds for stem cell differentiation are provided.Type: GrantFiled: September 16, 2009Date of Patent: April 21, 2015Assignees: Burnham Institute for Medical Research, Human Biomolecular Research InstituteInventors: Mark Mercola, Marcia Dawson, John Cashman, Paul J. Bushway
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Publication number: 20130190258Abstract: Methods and small molecule compounds for inhibition of cancer cell proliferation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, E, F, G, I, J, R, R1, R2, R2?, R3, R4, R5, R6, R7, R8, R9 are as described herein.Type: ApplicationFiled: January 24, 2013Publication date: July 25, 2013Inventors: John CASHMAN, Mark MERCOLA, Dennis SCHADE, Masanao TSUDA
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Publication number: 20130177535Abstract: Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the compound of Formula I and II: or a pharmaceutically acceptable salt or solvate thereof, wherein A, X, Q, R1, R2, R3, R4 are as described herein.Type: ApplicationFiled: July 2, 2012Publication date: July 11, 2013Inventors: John Cashman, Marion Lanier, Mark Mercola, Dennis Schade, Erik Willems
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Publication number: 20130157947Abstract: Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: or a chirally pure stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.Type: ApplicationFiled: March 23, 2012Publication date: June 20, 2013Inventors: MARK MERCOLA, John Cashman, Marion Lanier, Erik Willems, Dennis Schade
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Publication number: 20130123253Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.Type: ApplicationFiled: May 1, 2012Publication date: May 16, 2013Applicant: HUMAN BIOMOLECULAR RESEARCH INSTITUTEInventor: John CASHMAN
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Patent number: 8168635Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.Type: GrantFiled: June 20, 2005Date of Patent: May 1, 2012Assignee: Human BioMolecular Research InstituteInventor: John Cashman
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Publication number: 20110281356Abstract: Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4, R5, R5?, R6, R6?, R7, R7? are as described herein.Type: ApplicationFiled: May 13, 2011Publication date: November 17, 2011Applicants: Human BioMolecular Research Institute, Sanford-Burnham Medical Research InstituteInventors: Mark Mercola, John Cashman, Marion Lanier, Erik Willems
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Publication number: 20110264527Abstract: The present disclosure details apparatuses, methods, and systems for a code-mediated content delivery platform comprising a Graphical Code-Serving Interface and a Code Triggered Information Server (“GCSI/CTIS”). The GCSI/CTIS connects information encoding symbologies to graphical interface elements, thus expanding the useful information content and interactivity of graphical displays, advertisements, publications, broadcasts, and/or the like. GCSI/CTIS components facilitate wide ranging functionality, including generation of robust encoding symbologies, error-correction, media sampling and purchasing, social networking, and sales promotion programs.Type: ApplicationFiled: June 23, 2011Publication date: October 27, 2011Inventors: Dudley Fitzpatrick, Jason Alan Snyder, Glenn Thomas, John Cashman, Ed Jordan, Devon Strawn
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Publication number: 20100159596Abstract: Methods and small molecule compounds for stem cell differentiation are provided.Type: ApplicationFiled: September 16, 2009Publication date: June 24, 2010Applicants: Burnham Institute for Medical Research, Human BioMolecular Research InstituteInventors: Mark Mercola, Marcia Dawson, John Cashman
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Patent number: 7623637Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.Type: GrantFiled: January 2, 2007Date of Patent: November 24, 2009Assignee: ITXC IP Holdings S.a.r.l.Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
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Publication number: 20080261967Abstract: Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.Type: ApplicationFiled: June 20, 2005Publication date: October 23, 2008Inventor: John Cashman
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Publication number: 20070286846Abstract: This invention relates to a method for detoxication of inorganic or organic esters including OP nerve agents, cocaine, and respective analogs. More specifically, this invention pertains to the treatment of potentially neurotoxic esters or other ester groups by elaborating a more effective hydrolytic enzyme for therapeutic application. The structures of the synthesized OP analogs are provided. This invention also provides a diagnostic method and an Array Biosensor for detecting OP agents in biological and environmental samples.Type: ApplicationFiled: June 4, 2007Publication date: December 13, 2007Inventors: John Cashman, Jun Zhang
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Publication number: 20070165797Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.Type: ApplicationFiled: January 2, 2007Publication date: July 19, 2007Applicant: ITXC IP Holdings S.a.r.I.Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
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Patent number: 7167549Abstract: A system and method for reconciling the differences in pricing breakout definitions between telecommunication carriers so that rates and codes can be communicated between carriers in a format that is compatible with the systems of the respective carriers.Type: GrantFiled: August 11, 2003Date of Patent: January 23, 2007Assignee: ITXC IP Holdings, S.a.r.l.Inventors: Edward Hirschman, Jeffrey Bak, Avanish Pande, Aftab Hussain, John Cashman
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Patent number: 6455760Abstract: The present invention provides methods for using enhanced expression of nucleotide sequences encoding a flavin-containing monooxygenase (FMO) and suitable homologs thereof, to elicit desired traits, study biochemical pathways, and oxidize xenobiotics in plants.Type: GrantFiled: November 16, 2000Date of Patent: September 24, 2002Assignee: The Salk Institute of Biological StudiesInventors: Yunde Zhao, Joanne Chory, Christian Fankhauser, Detlef Weigel, John Cashman
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Patent number: 6405975Abstract: A system for aiding ground maneuvering of an airplane. The system includes at least one camera mounted on the airplane for generating video images of at last one gear with tires, preferably a main or nose landing gear and the surrounding ground. The cockpit of the airplane includes a video display device that displays the generated video images and a user interface that allows selection of the format for displaying the generated video images. A camera mounted within a moveable component of the airplane is mounted on a movable device that compensates for component movement. The system also includes a display generator for generating in real-time superimposed oversteer targets on the displayed video images. The video images with oversteer targets assist the pilot in determining the airplane's actual position relative to runways, taxiways, obstacles and other ground features and to maneuver a plane with a wide wheel track long wheelbase, or both accordingly.Type: GrantFiled: August 18, 1998Date of Patent: June 18, 2002Assignee: The Boeing CompanyInventors: Mithra M. K. V. Sankrithi, David W. McKenna, Mannon L. Wallace, Jr., Ronaldo O. Cabrera, Gary D. Reysa, Gerhard E. Seidel, John Yeeles, John Cashman