Patents by Inventor John S. Althaus

John S. Althaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11951086
    Abstract: A composition includes n-acyl ethanolamine, at least one cannabinoid, and at least one terpene. The composition may be in the form of a tablet.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: April 9, 2024
    Assignee: PURE GREEN PHARMACEUTICALS, INC.
    Inventors: Debra Kimless, John S. Althaus, Stephen Goldner
  • Publication number: 20230357578
    Abstract: This application disclose an airtight film including a plastic base layer; a ceramic sealing layer formed on the plastic base layer; and a polymer sealing layer. The polymer sealing layer includes many polymer molecules chemically bonding to the ceramic sealing layer as a result of polymerization reactions of at least one monomer on the ceramic sealing layer as opposed to from coating of a pre-polymerized polymer composition on the ceramic sealing layer.
    Type: Application
    Filed: May 12, 2023
    Publication date: November 9, 2023
    Inventors: Sung-Chan JO, Kyonghoon LEE, John S. ALTHAUS, Hyung Jin PARK
  • Publication number: 20230041595
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: September 9, 2022
    Publication date: February 9, 2023
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Patent number: 11441171
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: September 13, 2022
    Assignee: HANDYLAB, INC.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20220145030
    Abstract: This application features a method of forming a polymer layer on the surface of a substrate using a self-initiating monomer. A polymer layer is formed by polymerization of a monomer on a metal layer to fill or cover defects of the metal layer. The metal layer the polymer layer may be used as an airtight material.
    Type: Application
    Filed: July 20, 2021
    Publication date: May 12, 2022
    Inventors: Sung-Chan Jo, Kyonghoon LEE, John S. ALTHAUS, Hyung Jin PARK
  • Publication number: 20210047676
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: March 27, 2020
    Publication date: February 18, 2021
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Patent number: 10604788
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 31, 2020
    Assignee: HANDYLAB, INC.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20190390255
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: August 29, 2019
    Publication date: December 26, 2019
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20190382825
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: August 29, 2019
    Publication date: December 19, 2019
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Patent number: 10494663
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: December 3, 2019
    Assignee: HandyLab, Inc.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20190338344
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 7, 2019
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Patent number: 10443088
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: October 15, 2019
    Assignee: HandyLab, Inc.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20190284606
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: February 22, 2019
    Publication date: September 19, 2019
    Inventors: Betty Wu, John S. Althaus, Sundaresh N. Brahmasandra, Kalyan Handique, Nikhil Phadke
  • Patent number: 10364456
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: July 30, 2019
    Assignee: HANDYLAB, INC.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20190144620
    Abstract: Disclosed herein is a substrate-independently surface-coated polymer by aromatic-amine compound and a coating method thereof, and in particular to a substrate-independently surface-coated polymer and a coating method thereof wherein an aromatic compound in which two or more amines are substituted on benzene, is substrate-independently surface-coated. The substrate-independently surface-coated polymer characterized in that the surface of a polymer substrate is coated in such a way to react, using a surface modifier, an aromatic compound of the following structural formula on at least one surface of the polymer substrate having a nucleophilic functional group or an electrophilic functional group.
    Type: Application
    Filed: January 16, 2019
    Publication date: May 16, 2019
    Inventors: John S. Althaus, Kyong Hoon Lee, Gareth M. Fotouhi, Shinnosuke Inoue, Myoung-Han Kim
  • Patent number: 10214623
    Abstract: Disclosed herein is a substrate-independently surface-coated polymer by aromatic-amine compound and a coating method thereof, and in particular to a substrate-independently surface-coated polymer and a coating method thereof wherein an aromatic compound in which two or more amines are substituted on benzene, is substrate-independently surface-coated. The substrate-independently surface-coated polymer characterized in that the surface of a polymer substrate is coated in such a way to react, using a surface modifier, an aromatic compound of the following structural formula on at least one surface of the polymer substrate having a nucleophilic functional group or an electrophilic functional group.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: February 26, 2019
    Assignee: Core Biosystems Inc.
    Inventors: John S. Althaus, Kyong Hoon Lee, Gareth M. Fotouhi, Shinnosuke Inoue, Myoung-Han Kim
  • Publication number: 20170313837
    Abstract: Disclosed herein is a substrate-independently surface-coated polymer by aromatic-amine compound and a coating method thereof, and in particular to a substrate-independently surface-coated polymer and a coating method thereof wherein an aromatic compound in which two or more amines are substituted on benzene, is substrate-independently surface-coated. The substrate-independently surface-coated polymer characterized in that the surface of a polymer substrate is coated in such a way to react, using a surface modifier, an aromatic compound of the following structural formula on at least one surface of the polymer substrate having a nucleophilic functional group or an electrophilic functional group.
    Type: Application
    Filed: June 24, 2016
    Publication date: November 2, 2017
    Inventors: Kyong Hoon Lee, John S. Althaus, Gareth M. Gareth, Shinnosuke Inoue, Myoung-Han Kim
  • Publication number: 20150118684
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 30, 2015
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Patent number: 8852862
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: October 7, 2014
    Assignee: HandyLab, Inc.
    Inventors: Betty Wu, John S. Althaus, Nikhil Phadke, Sundaresh N. Brahmasandra, Kalyan Handique, Aaron Kehrer, Gene Parunak, Cecelia Haley, Ted Springer
  • Publication number: 20140030798
    Abstract: Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.
    Type: Application
    Filed: June 24, 2013
    Publication date: January 30, 2014
    Applicant: HANDYLAB, INC.
    Inventors: Betty WU, John S. Althaus, Sundaresh N. Brahmasandra, Kalyan Handique, Nikhil Phadke