Patents by Inventor John S. Fisher

John S. Fisher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130274893
    Abstract: A hydrogel plug is placed under stress during its curing stage, in one embodiment, by application of an externally applied force. The stress may also be induced during or after the dehydration process. The direction of the externally applied force increases the length, width, depth, or radial extent of the plug. The elastic limit of the plug is exceeded when the external force is applied so that the plug substantially retains its stressed size and shape when the externally applied force is removed. When the stretched or otherwise deformed dehydrated plug is hydrated, it substantially returns to the configuration it had prior to its dehydration and prior to the application of the externally applied force.
    Type: Application
    Filed: June 6, 2013
    Publication date: October 17, 2013
    Inventors: Frederick A. Ahari, John S. Fisher
  • Publication number: 20120328709
    Abstract: The present invention provides an aqueous composition and its use for dissolving blood clots in vivo or in clinical or research samples in vitro, said composition comprising at least one chaotropic agent, at least one chelating agent that complexes iron if the chaotropic agent does not complex iron and at least one surface-active emulsifier, the composition being buffered near pH 7.4. The process of dissolving the clot with the aqueous composition is advantageous because it is simple, inexpensive, rapid and can be applied in a variety of contexts, including basic research and clinical situations.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Applicant: SYNTHETECH PHARMACEUTICALS, LLC
    Inventors: John S. Fisher, Fred Ahari, Christopher Jon Perry, Lucjan J.J. Hronowski
  • Patent number: 8183889
    Abstract: An approach to rejecting input common-mode voltage variations in a sampler/converter that avoids the use of a differential amplifier in the signal path, and without introducing added distortion or noise. In one embodiment, the input common-mode variations are sensed on a pair of matched resistors that straddle the common mode analog inputs, on a node ‘Vcmi’. An alternative, switched-capacitor-based sensing scheme is also possible. Using this measured Vcmi, adjustments are then made to the rest of the sampler/converter to take out any variations observed at Vcmi.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: May 22, 2012
    Assignee: Kenet, Inc.
    Inventors: Lawrence J. Kushner, Michael P. Anthony, John S. Fisher
  • Publication number: 20110210763
    Abstract: An approach to rejecting input common-mode voltage variations in a sampler/converter that avoids the use of a differential amplifier in the signal path, and without introducing added distortion or noise. In one embodiment, the input common-mode variations are sensed on a pair of matched resistors that straddle the common mode analog inputs, on a node ‘Vcmi’. An alternative, switched-capacitor-based sensing scheme is also possible. Using this measured Vcmi, adjustments are then made to the rest of the sampler/converter to take out any variations observed at Vcmi.
    Type: Application
    Filed: August 26, 2010
    Publication date: September 1, 2011
    Applicant: Kenet, Inc.
    Inventors: Lawrence J. Kushner, Michael P. Anthony, John S. Fisher
  • Patent number: 7972619
    Abstract: A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: July 5, 2011
    Assignee: Biopsy Sciences, LLC
    Inventor: John S. Fisher
  • Patent number: 7786767
    Abstract: An approach to rejecting input common-mode voltage variations in a sampler/converter that avoids the use of a differential amplifier in the signal path, and without introducing added distortion or noise. In one embodiment, the input common-mode variations are sensed on a pair of matched resistors that straddle the common mode analog inputs, on a node ‘Vcmi’. An alternative, switched-capacitor-based sensing scheme is also possible. Using this measured Vcmi, adjustments are then made to the rest of the sampler/converter to take out any variations observed at Vcmi.
    Type: Grant
    Filed: January 29, 2008
    Date of Patent: August 31, 2010
    Assignee: Kenet, Inc.
    Inventors: Lawrence J. Kushner, Michael P. Anthony, John S. Fisher
  • Publication number: 20090088635
    Abstract: A permanent or temporary marker is embedded within a hydrogel plug used in a biopsy procedure to indicate the location of a suspicious lesion so that the marker may be found in a subsequent surgical procedure. A combination of at least one permanent and at least one temporary marker may be used. Inserts of differing sizes and shapes may also be placed into the hydrogel plugs during their manufacturing process and removed from the plugs after the plugs have cured so that air-filled cavities are left in the plug. These cavities are temporary but may be used to augment location of a permanent marker.
    Type: Application
    Filed: January 30, 2008
    Publication date: April 2, 2009
    Applicant: BIOPSY SCIENCE, LLC.
    Inventor: John S. Fisher
  • Patent number: 7416630
    Abstract: A method of fabricating a transmit/receive (T/R) module utilizing low temperature co-fired ceramic (LTCC) material in place of high temperature co-fired ceramic (HTCC) material and utilizing a combination of multiple lamination steps which also include forming a ceramic frame, as opposed to a metal ring frame, in the process. Brazing metallization is also utilized to attach heat sinks and lids as well as pin connectors. The formation of the pin connectors is provided on the side surface of the T/R module with a side printing process.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: August 26, 2008
    Assignee: Northrop Grumman Corporation
    Inventors: Rena Y. Jacobson, Tapan K. Gupta, John S. Fisher, III, Andrea Curbean
  • Publication number: 20080186061
    Abstract: An approach to rejecting input common-mode voltage variations in a sampler/converter that avoids the use of a differential amplifier in the signal path, and without introducing added distortion or noise. In one embodiment, the input common-mode variations are sensed on a pair of matched resistors that straddle the common mode analog inputs, on a node ‘Vcmi’. An alternative, switched-capacitor-based sensing scheme is also possible. Using this measured Vcmi, adjustments are then made to the rest of the sampler/converter to take out any variations observed at Vcmi.
    Type: Application
    Filed: January 29, 2008
    Publication date: August 7, 2008
    Applicant: Kenet, Inc.
    Inventors: Lawrence J. Kushner, Michael P. Anthony, John S. Fisher
  • Publication number: 20080161848
    Abstract: A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
    Type: Application
    Filed: April 6, 2007
    Publication date: July 3, 2008
    Applicant: BIOPSY SCIENCES, LLC
    Inventor: John S. Fisher
  • Patent number: 7329414
    Abstract: A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated form and moisture inherent in tissue at the site expands the sealant. The expanded sealant is formed of a hydrogel and is therefore more compatible to the surrounding tissue than the material of the tissue marker. The sealant and the tissue marker are both bioabsorbed over time.
    Type: Grant
    Filed: May 3, 2002
    Date of Patent: February 12, 2008
    Assignee: Biopsy Sciences, LLC
    Inventors: John S. Fisher, Frederick Ahari, Lucjan J. J. Hronowski
  • Patent number: 7225132
    Abstract: An identification code is assigned to a user by making a selection from a closed set of possible tokens. The selection is determined algorithmically by user identity data. The format of the identification code may comprise a sequence of natural language words chosen from closed sets and a separator character having a fixed value or a small range of possible values. The closed sets may be programmed in the recognition grammar of a speech interface to secure services such as banking.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: May 29, 2007
    Assignee: British Telecommunications plc
    Inventors: David J Attwater, John S Fisher, Paul F R Marsh
  • Patent number: 7001410
    Abstract: Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in dehydrated, unexpanded condition is pushed by a pushing device through the lumen of a needle until a first part of the plug is external to the opening and a second part is internal to the opening. The needle is then withdrawn while the position of the pushing device is maintained. The pushing device is then withdrawn, leaving the plug in sealing relation to the opening. The body's moisture causes the plug to expand to complete the sealing of the opening, or the expansion may be caused by exposure to air, light, or other stimulant. The opening may be formed in soft tissue, internal organs, or hard tissue. The plug seals the flow of liquid or gaseous biological fluids.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: February 21, 2006
    Assignee: Biopsy Sciences, LLC
    Inventors: John S. Fisher, Frederick Ahari, Lucjan J. J. Hronowski
  • Patent number: 6994712
    Abstract: A clip and a bioabsorbable marker are employed to mark a biopsy site. The former provides a permanent marker that is clamped onto tissue and that cannot migrate from the site over time. The latter is gradually bioabsorbed over time but the time may vary widely from weeks to months. In most embodiments, the clip and marker are integrally formed with one another at the time of manufacture. In one embodiment, the clip and marker are independently made but are joined to one another during the site-marking process. The markers are deployed by core biopsy needles of the type employing a vacuum, of the type that does not employ a vacuum, and by coaxial biopsy needles.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: February 7, 2006
    Assignee: Biopsy Sciences, LLC
    Inventors: John S. Fisher, Frederick Ahari
  • Patent number: 6979239
    Abstract: Slots or apertures are formed in the connector shroud of a T/R module in a plane perpendicular to the axis of the connector so as to allow plating solution to flow freely through the entire inner portion of the connector, particularly the rear portion, during fabrication of the T/R module. The slots are formed prior to the shroud being brazed on to the module substrate. By allowing plating solution to flow through the connector, the interior of the connector can be more thoroughly plated, thereby improving the yield of the assembly while reducing cost.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: December 27, 2005
    Assignee: Northrop Grumman Corporation
    Inventors: Patrick K. Richard, Edward L. Rich, III, Kevin L. Ebersole, Angela J. Martin, Tapan K. Gupta, David W. Strack, John S. Fisher, III
  • Patent number: 6908440
    Abstract: A biopsy needle scrapes tissue of cellular size from a lesion during repeated proximal-to-distal thrusts of the needle along its longitudinal axis of symmetry. A first sharp edge, formed by a beveled distal end of the needle, scrapes tissue during proximal-to-distal travel of the needle. A second sharp edge is provided by a transversely disposed slot formed in the needle near the first sharp edge. The second sharp edge also scrapes tissue during proximal-to-distal travel of the needle. The second sharp edge may be coincident with an exterior surface of the needle, elevated with respect to the exterior surface, or recessed with respect to the exterior surface. Another embodiment includes a hinge for enabling pivotal movement of the second sharp edge.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: June 21, 2005
    Assignee: Biopsy Sciences, LLC
    Inventor: John S. Fisher
  • Patent number: 6890309
    Abstract: A dual action biopsy needle scrapes tissue of cellular thickness from a lesion during forward and rearward reciprocations of the needle along its longitudinal axis of symmetry. A first sharp edge, formed by a beveled distal end of the needle, scrapes tissue during proximal-to-distal travel of the needle. A second sharp edge is provided by a transversely disposed slot formed in the needle near the first sharp edge. The second sharp edge scrapes tissue during distal-to-proximal travel of the needle. In a first embodiment, the second sharp edge is coincident with an exterior surface of the needle. In a second embodiment, the second sharp edge is elevated with respect to the exterior surface and in a third embodiment the second sharp edge is recessed. Additional embodiments include a second slot, a channel, and a hinge for enabling pivotal movement of the second and third sharp edges.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: May 10, 2005
    Assignee: Biopsy Sciences, LLC
    Inventor: John S. Fisher
  • Patent number: 6872185
    Abstract: A biopsy needle scrapes tissue of cellular thickness from a lesion during repeated proximal-to-distal thrusts of the needle along its longitudinal axis of symmetry. A first sharp edge, formed by a beveled distal end of the needle, scrapes tissue during proximal-to-distal travel of the needle. A second sharp edge is provided by a transversely disposed slot formed in the needle near the first sharp edge. The second sharp edge also scrapes tissue during proximal-to-distal travel of the needle. The second sharp edge may be coincident with an exterior surface of the needle elevated with respect to the exterior surface, or recessed with respect to the exterior surface. Another embodiment includes a hinge for enabling pivotal movement of the second sharp edge.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: March 29, 2005
    Assignee: Biopsy Sciences, LLC
    Inventor: John S. Fisher
  • Patent number: 6793668
    Abstract: A balloon angioplasty or stenting apparatus includes a guide wire, a balloon catheter ensleeving the guide wire, and a guide catheter ensleeving the balloon catheter. The balloon catheter has slots formed in it to define elongate members between the slots. A joint is formed at the proximal, distal, and mid-point of each elongate member. Displacing the proximal and distal joints toward and away from one another causes the respective middle joints to displace radially outwardly and inwardly, respectively. A mesh that captures emboli while allowing blood perfusion partially overlies the jointed members is opened and closed when the jointed members are opened and closed. A guide wire having an outer coil and an inner rod slideably received within it has jointed members formed in the outer coil. The mesh is opened and closed by axially retracting and advancing the inner rod with respect to the outer coil, respectively.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: September 21, 2004
    Inventor: John S. Fisher
  • Patent number: 6790185
    Abstract: A bioabsorbable sealant plug that expands in response to contact with moisture in a mammalian body is optimally positioned in a biopsy tract to seal the biopsy tract when a biopsy procedure is completed. In a first method, the leading end of the sealant plug is advanced through the lumen of a coaxial needle by a plunger until a leading end of a supporting leg abuts the patient's skin surface. A second method is performed with a pistol-shaped tool having a trigger that enables adjustment of the plunger. A third embodiment includes a plunger having a bifurcated end that grasps the plug. A fourth embodiment has a turning nut that causes compression of a gasket that clamps down on the plug. A supporting rod and coaxial needle are in parallel relation to one another in a fifth embodiment.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: September 14, 2004
    Assignee: Biopsy Sciences, LLC
    Inventors: John S. Fisher, Frederick Ahari