Patents by Inventor John S. Lee

John S. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140120100
    Abstract: The inventors have discovered that both soluble erythropoietin-binding protein and antibodies against the erythropoietin-binding protein, when they are administered to a mammal along with erythropoietin (Epo), prevent or reduce the blood pressure increase normally caused by erythropoietin, while not affecting the hematocrit increase that is the purpose of Epo treatment. The invention provides a method of treating anemia in a mammal involving: administering erythropoietin (Epo) to the mammal; and administering to the mammal an agent selected from a soluble Epo-binding protein (Epo-bp), a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor, and a combination thereof. The invention also provides a method of reducing hypertension in a mammal receiving Epo, and pharmaceutical compositions containing a soluble Epo-bp and/or a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor.
    Type: Application
    Filed: September 30, 2013
    Publication date: May 1, 2014
    Inventors: Jong Y. Lee, John S. Lee, Mary S. Lee
  • Publication number: 20120064079
    Abstract: The inventors have discovered that both soluble erythropoietin-binding protein and antibodies against the erythropoietin-binding protein, when they are administered to a mammal along with erythropoietin (Epo), prevent or reduce the blood pressure increase normally caused by erythropoietin, while not affecting the hematocrit increase that is the purpose of Epo treatment. The invention provides a method of treating anemia in a mammal involving: administering erythropoietin (Epo) to the mammal; and administering to the mammal an agent selected from a soluble Epo-binding protein (Epo-bp), a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor, and a combination thereof. The invention also provides a method of reducing hypertension in a mammal receiving Epo, and pharmaceutical compositions containing a soluble Epo-bp and/or a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor.
    Type: Application
    Filed: March 10, 2011
    Publication date: March 15, 2012
    Inventors: Jong Y. Lee, Mary S. Lee, John S. Lee
  • Patent number: 7638333
    Abstract: Using the nontoxic PA protein from B. anthracis, a method and composition for use in inducing an immune response which is protective against anthrax in subjects is described.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: December 29, 2009
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John S. Lee, Peter Pushko, Michael D. Parker, Jonathan F. Smith, Susan L. Welkos
  • Patent number: 7374931
    Abstract: Using nucleic acids encoding mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: May 20, 2008
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John S. Lee, Peter Pushko, Jonathan F. Smith, Robert G. Ulrich
  • Patent number: 7312089
    Abstract: The invention is based on the development of several sensitive and simple methods for detecting erythropoietin and the erythropoietin receptor and associated antibodies. The methods and reagents are useful for differential diagnosis in Epo and EpoR related clinical problems. Methods and kits for simultaneous measurement of erythropoietin and erythropoietin receptor in a biological sample are described.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: December 25, 2007
    Inventors: Jong Y. Lee, Mary S. Lee, John S. Lee
  • Patent number: 7311367
    Abstract: Apparatus and methods are provided. At least one clamping finger of a movable tray of a compact disc printer pushes against an outer periphery of a compact disc disposed on a surface of the tray to clamp the compact disc between the clamping finger and a pair of studs that protrude from the surface of the tray and engage a periphery of a hole passing through a center of the compact disc. A carriage of the printer for moving an ink jet cartridge attached thereto across the compact disc to deposit an image on the compact disc may include a sensor. The sensor can be used to determine the presence of a compact disc on the tray, whether the compact disc is clamped to the tray, and a dimension of the compact disc, and to perform a calibration method.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: December 25, 2007
    Assignee: Rimage Corporation
    Inventors: Phillip C. Salisbury, Douglas J. Lenz, John S. Lee, Westin W. Nelson
  • Patent number: 7092320
    Abstract: A compact disc processing system allows for more efficient processing of compact discs. The system included a transporter mechanism that can grip and transport more than one compact disc at a time. As such, a second disc can be gripped while a first disc is being processed. This eliminates the need to wait for processing operations, such as recording or printing, to be completed prior to transporting the second disc. The system includes a gripping head with at least two vacuum controlled mechanisms for selectively gripping the discs. A disc organizer can be provided which includes trays that can be used to store discs for selective retrieval. The organizer eliminates the difficulty encountered in locating a processed disc from a large stack of discs.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: August 15, 2006
    Assignee: Rimage Corporation
    Inventors: John S. Lee, David J. Suden, Westin W. Nelson, Phillip C. Salisbury, Darrin William Piekkola
  • Patent number: 6962157
    Abstract: A hair extension device is provided wherein the hair extension device comprises: at least one comb; at least one bendable member having opposing ends, a first end being attached to the comb; and at least one length of hair attached to the second end of the bendable member wherein the end user forms a ponytail and the comb is attached onto the end user's existing hair adjacent to the ponytail and the bendable member is bent around the ponytail and shaped to provide for a plurality of hairstyles.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: November 8, 2005
    Assignee: Soho Fashion, Inc
    Inventors: John S. Lee, Su-Jin Lee
  • Patent number: 6883525
    Abstract: The invention provides for a hair extension device and a method of manufacture of the hair extension device. The hair extension device includes at least one length of hair attached to a bendable wire and a comb attached to the wire. The method of manufacture provides the steps for attaching the hair to the formable wire and attaching the formable wire to a comb.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: April 26, 2005
    Assignee: Soho, Inc.
    Inventors: John S. Lee, Su-Jin Lee
  • Publication number: 20040226571
    Abstract: The invention provides for a hair extension device and a method of manufacture of the hair extension device. The hair extension device includes at least one length of hair attached to a bendable wire and a comb attached to the wire. The method of manufacture provides the steps for attaching the hair to the formable wire and attaching the formable wire to a comb.
    Type: Application
    Filed: May 14, 2003
    Publication date: November 18, 2004
    Inventors: John S. Lee, Su-Jin Lee
  • Patent number: 6770479
    Abstract: Using the nontoxic PA protein from B. anthracis, a method and composition for use in inducing an immune response which is protective against anthrax in subjects is described.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: August 3, 2004
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John S. Lee, Peter Pushko, Michael D. Parker, Jonathan F. Smith, Susan L. Welkos
  • Publication number: 20040009183
    Abstract: Using nucleic acids encoding mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.
    Type: Application
    Filed: April 2, 2003
    Publication date: January 15, 2004
    Inventors: John S. Lee, Peter Pushko, Jonathan F. Smith, Robert G. Ulrich
  • Publication number: 20040009945
    Abstract: Using the nontoxic PA protein from B. anthracis, a method and composition for use in inducing an immune response which is protective against anthrax in subjects is described.
    Type: Application
    Filed: May 21, 2003
    Publication date: January 15, 2004
    Inventors: John S. Lee, Peter Pushko, Michael D. Parker, Jonathan F. Smith, Susan L. Welkos
  • Patent number: 6632640
    Abstract: Using nucleic acids encoding mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: October 14, 2003
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John S. Lee, Peter Pushko, Jonathan F. Smith, Robert G. Ulrich
  • Publication number: 20030180822
    Abstract: Methods and kits for simultaneous measurement of erythropoietin and erythropoietin receptor in a biological sample are described.
    Type: Application
    Filed: October 4, 2002
    Publication date: September 25, 2003
    Inventors: Jong Y Lee, Mary S Lee, John S Lee
  • Patent number: 6495143
    Abstract: Using the nontoxic heavy chain fragment from botulinum neurotoxins A-G, compositions and methods of use in inducing an immune response which is protective against intoxication with botulinum in subjects is described.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: December 17, 2002
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John S. Lee, Peter Pushko, Jonathan F. Smith, Michael Parker, Mark T. Dertzbaugh, Leonard Smith
  • Patent number: 6341778
    Abstract: The invention comprises a method for increasing the payout for the main wager of the game of blackjack or Twenty-One and/or for providing a side bet opportunity during the game of blackjack or Twenty-One which are based upon the point-spread between the players hand and the dealers hand. In one embodiment, a pointspread of 1, 2, 3, or 4 would result in 1×, 1.5×, 2×, or 10× payout, respectively, of the side wager. In another embodiment, a pointspread of 1, 2, 3, or 4 would result in 1×, 2×, 3×, or 5× payout, respectively, of a side bet. In another embodiment, a pointspread of 0, 1, 2, 3, or 4 would result in 0.5× , 1× , 1.5× , 3× , or 5× payout, respectively, of a side bet. The game allows for variations in the rules and for other types of side-betting opportunities while maintaining the excitement of a multiple pointspread payout at the resolution of the hand.
    Type: Grant
    Filed: November 29, 1999
    Date of Patent: January 29, 2002
    Inventor: John S. Lee
  • Patent number: 6041703
    Abstract: A compact disc transporter is described for transporting a compact disc between multiple process stations. These stations may include a printer, a recorder, a verifier, and a compact disc supply station. Methods have been described for pre-positioning a compact disc prior to printing so that an image located on the compact disc can be positioned for subsequent printing operations. A camera may be used in conjunction with a processor to rotatably position a compact disc into a preferred position prior to a printing operation. An optical sensor is also described for detecting a mark, index mark or other image for positioning a compact disc to a preferred rotational position.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: March 28, 2000
    Assignee: Rimage Corporation
    Inventors: Phillip C. Salisbury, David J. Rother, Roger E. Haro, John S. Lee, Donald Hollerich
  • Patent number: 5914918
    Abstract: An apparatus for recording and verifying information recorded on compact disks and for printing label information on the disks, and a method of operating the apparatus, wherein the respective recorders, verifiers, and printers are vertically stacked in a housing, and a vertically movable carriage is arranged to transport compact disks to each of the stacked devices. A rotatable carousel is mounted to the housing beneath the carriage; the carousel having multiple bins for receiving and holding compact disks. A computer processor controls the actuation of the respective devices, the carriage, and the carousel, to sequentially process unrecorded compact disks through the steps of recording, verifying and printing, and to reject compact disks which have failed the verification tests. A camera may be connected to the housing and uses in conjunction with the computer processor to rotatably position a compact disk into a preferred position prior to the printing step.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: June 22, 1999
    Assignee: Rimage Corporation
    Inventors: John S. Lee, Roger E. Haro, David Rother, Donald Hollerich
  • Patent number: 5734629
    Abstract: An apparatus for recording and verifying information recorded on compact disks and for printing label information on the disks, and a method of operating the apparatus, wherein the respective recorders, verifiers, and printers are vertically stacked in a housing, and a vertically movable carriage is arranged to transport compact disks to each of the stacked devices. A rotatable carousel is mounted to the housing beneath the carriage; the carousel having multiple bins for receiving and holding compact disks. A computer processor controls the actuation of the respective devices, the carriage, and the carousel, to sequentially process unrecorded compact disks through the steps of recording, verifying and printing, and to reject compact disks which have failed the verification tests. A camera may be connected to the housing and used in conjunction with the computer processor to rotatably position a compact disk into a preferred position prior to the printing step.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: March 31, 1998
    Assignee: Rimage Corporation
    Inventors: John S. Lee, Roger E. Haro, David Rother, Donald Hollerich