Patents by Inventor John To

John To has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200172905
    Abstract: A ribonucleic acid compound is disclosed, the ribonucleic acid compound comprising, or consisting of, an RNA sequence having at least 90% sequence identity to SEQ ID NO: 1, wherein said RNA sequence has a length of 29 nucleotides or fewer, and wherein the RNA sequence is capable of binding to a transferrin receptor (TfR).
    Type: Application
    Filed: August 10, 2018
    Publication date: June 4, 2020
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib
  • Publication number: 20200172982
    Abstract: Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).
    Type: Application
    Filed: September 13, 2019
    Publication date: June 4, 2020
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Douglas W. Mahoney, Tracy C. Yab, Graham P. Lidgard, Hatim T. Allawi
  • Publication number: 20200173599
    Abstract: A pipe rehabilitation system and/or robot can be used inside a pipe to measure characteristics of branch conduits, install plugs into branch conduits before the pipe is lined with a liner, remove portions of plugs and liners after lining to restore fluid communication between the pipe and branch conduits, and/or install fittings into the branch conduits to connect the liner to the branch conduits. A probe can measure characteristics of a branch conduit. A tool can install plugs and/or fittings into the branch conduits. A linkage can connect a tool to a robotic tractor so that the connected elements can navigate through a main pipe. A visualization system can aid in aligning a robot with a branch conduit. Height-adjustable braces can support robotic tools in a pipe. A plug can include integrated locating features and/or movable parts that enable expanding the plug to seal with the branch conduit.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Inventors: Rick Baxter, Robert Kodadek, Hermann Herrlich, Steven McKeefrey, John Webster, Brian Lynn, John Jayne, Ryan Goldband, Michael Hauser, George Bontus
  • Publication number: 20200173282
    Abstract: A hose for use with a blower and an underground vault. The hose surviving an explosion initiated inside the underground vault. The hose is blast-resistant, arc-flash-resistant, and fire-resistant. A first end of the hose is connectable to the blower and configured to receive fresh air from the blower when connected thereto. The hose conducts the fresh air to a second end of the hose. The second end is positionable inside the underground vault wherein the fresh air provides sufficient breathable air to any personnel present in the underground vault.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 4, 2020
    Inventor: Glen John Bertini
  • Publication number: 20200173223
    Abstract: A fenestration system includes a chassis formed from left and right chassis stiles, and top and bottom chassis rails. The left and right chassis stiles having an outside longitudinal groove, an outside longitudinal ridge, an inside longitudinal groove and an inside longitudinal ridge. The top and bottom chassis rails having an outside longitudinal groove, an outside longitudinal ridge, an inside longitudinal groove and an inside longitudinal ridge. Outside stile covers are configured to engage the longitudinal outside groove and the longitudinal outside ridge of the chassis stile. Inside stile covers are configured to engage the inside longitudinal groove and the inside longitudinal ridge of the chassis stile. Outside rail covers are configured to engage the longitudinal outside groove and the longitudinal outside ridge of the chassis rail. Inside rail covers are configured to engage the inside longitudinal groove and the inside longitudinal ridge of the chassis rail.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 4, 2020
    Applicant: Sunrise Windows, LLC
    Inventors: John H. Walsh, Gary J. Spoering, Rolf J. Ohrstrom
  • Publication number: 20200173326
    Abstract: A method of reducing the emission of nitrogen oxides (NOx) during system startup of a power generating system may include igniting a combustion turbine thereby generating exhaust, supplying the exhaust to a catalyst bed comprising a selective catalytic reduction (SCR) catalyst, injecting an initial pulse of ammonia into the exhaust during a storage period such that the NOx reacts with the ammonia and is stored in the catalyst bed as ammonium nitride nitrate (AN) during the storage period; and injecting a scheduled amount of ammonia into the exhaust during a transition period such that the stored AN is decomposed as temperatures increase and NOx is converted via standard and fast SCR reactions during the transition period.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 4, 2020
    Inventors: John Grant McDaniel, Christian Skov Heiberger, Daniel Scott Richardson, Paul Zach Cummins, III, Andrew Cameron Robertson
  • Publication number: 20200173228
    Abstract: A vertical cellular drape configured for use as a covering for an architectural structure may include a front drape panel and a rear drape panel. The front and rear drape panels may be coupled to each other so that the drape panels are configured to be moved laterally between an extended position and a retracted position to cover or expose an adjacent architectural structure, as desired. In addition, the drape panels may be configured to be positioned relative to each other such that a plurality of vertically oriented, internal cells are defined between the drape panels.
    Type: Application
    Filed: February 6, 2020
    Publication date: June 4, 2020
    Inventors: John D. Rupel, Ren Judkins, Scott R. Cheslock, Toralf H. Strand
  • Publication number: 20200173661
    Abstract: An interface for double-skin combustor liner comprises an annular ceramic matrix composite (CMC) body. The annular body extends from a first side to a second side, the first and second sides each having an annular inner joint groove configured to receive a CMC combustor skin and an annular outer joint groove configured to receive a metal combustor skin. The outer joint groove is radially outward of the inner joint groove. A combustor and an gas turbine engine with the interface are also provided.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 4, 2020
    Inventors: Tin-Cheung John HU, Robert SZE
  • Publication number: 20200172789
    Abstract: A well fluid composition includes powdered polylactic acid having a selected melting temperature below a lowest expected temperature of a subsurface formation into which the composition is to be introduced. The composition includes powdered polymer suspension aide and/or viscosifier in an amount which when hydrated enables suspension of the powdered polylactic acid in liquid for at least 2 hours and up to 24 hours. The powdered polylactic acid and the powdered polymer solids suspension aide and/or viscosifier are mixed with a liquid capable of hydrating the powdered polymer solids suspension aide and/or viscosifier.
    Type: Application
    Filed: November 29, 2018
    Publication date: June 4, 2020
    Inventors: Nathan R. Hutchings, John Paxton Monsour, Stewart Simpson
  • Publication number: 20200172867
    Abstract: The invention includes compositions and methods related to multimodal therapies, e.g., for treating cardiovascular diseases and metabolic disorders. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cardiovascular disease or metabolic disorder.
    Type: Application
    Filed: July 19, 2017
    Publication date: June 4, 2020
    Inventors: Tom Wickham, Tiffany F. Chen, Torben Straight Nissen, Nathan Dowden, Robert J. Deans, John Round, Avak Kahvejian, Jordi Mata-Fink, Noubar B. Afeyan
  • Publication number: 20200172823
    Abstract: Certain glycol ether diesters have improved lubrication properties.
    Type: Application
    Filed: June 26, 2018
    Publication date: June 4, 2020
    Applicant: Dow Global Technologies LLC
    Inventors: John B. Cuthbert, Felipe A. Donate, Matthew W. Entorf, Ashish Kotnis, Ellen D. Hock, Lindsey A. Clark
  • Publication number: 20200172877
    Abstract: Improved methods for the production of reassortant influenza viruses are provided.
    Type: Application
    Filed: September 26, 2019
    Publication date: June 4, 2020
    Applicants: Seqirus UK Limited, Synthetic Genomics, Inc.
    Inventors: Philip DORMITZER, Peter MASON, Pirada SUPHAPHIPHAT, Daniel GIBSON, David WENTWORTH, Timothy STOCKWELL, John GLASS
  • Publication number: 20200173124
    Abstract: A system of actively introducing opposite phase vibrations to reduce or cancel vibrations caused by operating a snow plow. The invention also relates to a method of actively introducing such opposite phase vibrations.
    Type: Application
    Filed: October 15, 2019
    Publication date: June 4, 2020
    Inventors: Michael G. D'Andrea, John Cronin
  • Publication number: 20200173231
    Abstract: A door assembly having a door panel fixed proximate a top edge of the door panel to a drum, the drum being rotatable in a first direction and a second direction to wind or open and unwind or close the door panel. The door assembly includes a first side column and a second side column, each positioned proximate a doorway which is opened and closed by the door panel. Each side column includes a guide track positioned to guide one of the first vertical edge or the second vertical edge of the door panel as the door panel is moved. A first column of drive teeth is positioned along the first vertical edge and a second column of drive teeth positioned along the second vertical edge, wherein each of the first column of drive teeth and the second column of drive teeth are formed by a plurality of adjacent drive teeth, each drive tooth in each plurality of drive teeth abutting an adjacent drive tooth as the door panel is wound and unwound from the drum.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Inventors: Brian Norbert Drifka, Seth Edward Kampa, Gabriel John Biertzer
  • Publication number: 20200173157
    Abstract: Disclosed is an in-the-bowl dispensing device designed to dispense a composition after the flush of the toilet bowl is complete. In this manner the composition is retained in the toilet bowl until the toilet bowl is flushed by the next user.
    Type: Application
    Filed: June 5, 2018
    Publication date: June 4, 2020
    Inventors: Kris CARVER, Jesse DELGIGANTE, Henry Matthew Lawrence FLETCHER, John Kenneth HAINSWORTH, Iain Christopher SMITH, Alim THAWER
  • Publication number: 20200173262
    Abstract: A system for use with a connection comprising a terminus opening into an underground vault. The system includes a perturbation detector and a system controller. The perturbation detector is configured to detect values of each of one or more properties and transmit a signal encoding the values to the system controller. The system controller is configured to receive the signal, use at least one of the values to determine whether a fire is occurring or has occurred, and alert a user when the system controller determines that the fire is occurring or has occurred.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 4, 2020
    Inventors: Glen John Bertini, David C. Busby, Weston Philips Chapin Ford, Jeffrey Andrew Thomas
  • Publication number: 20200173593
    Abstract: A flow splitter may include an inlet, at least two outlets, and an internal vane comprising a first end corresponding to the inlet and a second end corresponding to the at least two outlets, wherein the internal vane is configured to turn, between the first end and the second end, an internal flowing fluid from 0 degrees to a degree between about 60 degrees and 150 degrees. Methods of dividing fluid flow are also provided.
    Type: Application
    Filed: June 25, 2018
    Publication date: June 4, 2020
    Inventors: George Martin Tolhurst, Alan C. Anderson, John Robert Andras, Jonathan Bowen Wickliff
  • Publication number: 20200173263
    Abstract: A flow restrictor for installation in a connection having a terminus opening into an underground vault. The flow restrictor includes an annular restriction device and a concentration member. The annular restriction device is configured to be installed in the annulus near the terminus opening and to restrict a flow of one or more gases through the annulus of the connection. The concentration member is configured to concentrate the flow and includes a through-channel configured to allow the concentrated flow to flow between the underground vault and the annulus.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 4, 2020
    Inventors: Glen John Bertini, David C. Busby
  • Publication number: 20200174838
    Abstract: Server resources in a data center are disaggregated into shared server resource pools, including an accelerator (e.g., FPGA) pool. Servers are constructed dynamically, on-demand and based on workload requirements, by allocating from these resource pools. According to this disclosure, accelerator utilization in the data center is managed proactively by assigning accelerators to workloads in a fine granularity and agile way, and de-provisioning them when no longer needed. In this manner, the approach is especially advantageous to automatically provision accelerators for data analytic workloads. The approach thus provides for a “micro-service” enabling data analytic workloads to automatically and transparently use FPGA resources without providing (e.g., to the data center customer) the underlying provisioning details. Preferably, the approach dynamically determines the number and the type of FPGAs to use, and then during runtime auto-scales the FPGAs based on workload.
    Type: Application
    Filed: November 29, 2018
    Publication date: June 4, 2020
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Min LI, John A. BIVENS, Ruchi MAHINDRU, HariGovind V. RAMASAMY, Yaoping RUAN, Valentina SALAPURA, Eugen SCHENFELD
  • Publication number: 20200173400
    Abstract: A valve form exhaust gas recirculation Mac in an engine includes a first barrel connectable to a first group of cylinders, a second barrel connectable to a second group of cylinders, and a center barrel between the first and second barrels and connectable to an intake oft he engine. A poppet valve with two valve heads mounted on a valve stem is provided to open and close openings between the first and second barrels, with one of the valve beads of the poppet valve opening into the center barrel Vanes are provided-in the center barrel to direct flow from the opening by the valve bead that opens into the center barrel toward the outlet opening.
    Type: Application
    Filed: August 15, 2017
    Publication date: June 4, 2020
    Applicant: VOLVO TRUCK CORPORATION
    Inventors: Jian LI, John LOWE