Abstract: A method and apparatus for accessing, processing and manipulating data in an OLAP database. According to one aspect, the present invention comprises a user interface configured for accessing, processing and manipulating data in an OLAP cube. According to another aspect, the present invention comprises a calculation engine for manipulating and managing data in the OLAP cube.

Abstract: A modular and portable crane and forklift device is provided which is easily assembled and disassembled without requiring extraneous tools. The device composed of tubing components engaged to form an elongated lifting strut employs the force that a user imparts on a winch which is communicated to one or more cables and pulleys, to elevate and lower a load. The winch is positionable at ground level or an elevated position.

Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.

Abstract: The present invention relates to an ionic liquid comprising an anion and a cation, wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.

Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR. The invention is based in part on the discovery of ROR modulators which interact with RORa and/or RORy and thereby inhibit or induce RORa and/or RORy-activity, and RORa- and/or RORy-regulated target gene and protein expression.

Abstract: The present invention relates to a consumer good product comprising: (a) a composition comprising or consisting of a mixture of: (i) chitin nanofibrils; (ii) lignin or a derivative thereof; and (iii) optionally, at least one polymer or co-polymer; and (b) at least one consumer goods ingredient.

Abstract: Conjugates of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes with a variety of conjugating members are used in the formation of dinuclear metal complexes which bind to phosphate esters. By virtue of their conjugated forms, the complexes are incorporated into chromatographic media, affinity binding reagents, and dyes, which make the complexes useful in a wide range of assays, separations, and purifications. In addition, dinuclear metal complexes of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes that are not so conjugated are used in the detection of phosphate esters of biological species by either MALDI-TOF mass spectrometry or by dye displacement.

Abstract: There is provided a breech lock coupling for coupling riser sections together. The breech lock coupling may be used non-pre-loaded or pre-loaded according to the user's preferences. In addition, the breech lock coupling may be disassembled for inspection and maintenance and reassembled. A locking ring secures two coupling components together. The coupling components may be attached to opposite ends of the riser sections, such as via welding. The locking ring may be pre-attached to the first coupling component for easy storage and fast assembly. Assembly of the riser may be accomplished by inserting the second coupling component into the locking ring and the first coupling component, then rotating the locking ring with respect to the second component. Furthermore, the coupling may be pre-loaded by tightening fasteners on the locking ring to provide a more stable coupling. Unlike with traditional riser couplings, the pre-load fasteners may be tightened via hand-held tools.

Abstract: Slab gel cassettes for use in electrophoretic analyzes of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

Abstract: A riser disconnect/reconnect system having a disconnection package (RDP) and a modified lower marine riser package (LMRP) are provided for quick disconnection of the marine drilling riser (MDR) from the LMRP to facilitate access to the LMRP or BOP stack. The RDP includes a flex joint and a hydraulically-actuated release connector (RC) with a connecting mandrel that engages a modified LMRP. In an emergency, the RDP is disconnected from the LMRP allowing access to the BOP stack for intervention. The RDP may be disconnected from the LMRP for recovery of the LMRP or BOP stack to the surface for repair or maintenance without recovering the MDR. The RC joins the flex joint to the uppermost annular blowout preventer in the LMRP. The release connector can be used in a standard or inverted position. Also provided are structural cages with complementary stab plates allowing access to various bypass ports and controls.

Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR. The invention is based in part on the discovery of ROR modulators which interact with RORa and/or RORy and thereby inhibit or induce RORa and/or RORy-activity, and RORa- and/or RORy-regulated target gene and protein expression.

Abstract: An adjuvant composition which comprises an anionic macromolecule component particularly an ionic polysaccharide such as DEAE-dextran, and a saponin component, particularly an immunostimulating complex component. Immunogenic compositions comprising an immunogen and this adjuvant composition are also disclosed together with methods of use thereof.

Abstract: The invention relates to MIF inhibitors; compositions comprising an effective amount of a MIF inhibitor; and methods for treating or preventing diseases associated with MIF.

Abstract: A riser disconnect/reconnect system having a disconnection package (RDP) and a modified lower marine riser package (LMRP) are provided for quick disconnection of the marine drilling riser (MDR) from the LMRP to facilitate access to the LMRP or BOP stack. The RDP includes a flex joint and a hydraulically-actuated release connector (RC) with a connecting mandrel that engages a modified LMRP. In an emergency event, the RDP is disconnected from the LMRP allowing access to the BOP stack for intervention. The RDP may be disconnected from the LMRP for recovery of the LMRP or BOP stack to the surface for repair or maintenance without recovering the MDR. The RC joins the flex joint to the uppermost annular blowout preventer in the LMRP. The release connector can be used in a standard or inverted position. Also provided are structural cages with complementary stab plates allowing access to various bypass ports and controls.

Abstract: An apparatus and method for removing waste from a soiled container that houses laboratory animals and has an opening is disclosed. The apparatus includes a conveyor having a receiving end for receiving containers from a stack of containers. The stack is disposed such that the openings are upwardly oriented. The apparatus also includes a manipulator that aligns with and engages an uppermost container of the stack and causes the uppermost container to be separated from the stack and to be flipped over onto the receiving end of the conveyor such that the opening is downwardly disposed. Waste discarded from the container falls through openings in the conveyor, and a waste receptacle disposed below the conveyor collects the discarded waste. The conveyor advances to transport the container away from the receiving end toward a discharge end of the conveyor.

Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.

Abstract: The present invention relates to an ionic liquid comprising an anion and a cation, wherein the cation is a primary, secondary or tertiary ammonium ion containing a protonated nitrogen atom.

Abstract: The invention relates to ROR modulators; compositions comprising an effective amount of a ROR modulator; and methods for treating or preventing diseases associated with ROR.

Abstract: The invention relates to MIF inhibitors; compositions comprising an effective amount of a MIF inhibitor; and methods for treating or preventing diseases associated with MIF.