Abstract: A method for post-processing to synchronize audio data with vehicle data includes generating an artificial sound data based on time-series vehicle data. The method includes determining an offset that maximizes cross-correlation between the artificial sound data and recorded audio data. The method also includes shifting one or more of the time-series data and the recorded audio data relative to each other in time based on the offset. The shift may be used to generate or render a synchronized set of time-series data and recorded audio data.

Abstract: A virtual reality (VR) system supports improved interactive control processes/services. These interactive control processes/services include detecting movement of a controller associated with a virtual reality (VR) environment, determining an angle of rotation based on the movement, determining a magnitude of force associated with the movement, determining a path in the VR environment that corresponds to the angle of rotation and the magnitude of force, and projecting the path in the VR environment.

Abstract: A computer apparatus, such as a validator node, for validating data records in a distributed electronic ledger may be configured to receive a proposed data record submitted by an originating agent of an originating agency to a distributed ledger. In response to the proposed incident-related data record, other agents within the originating agency may, based on validation criteria, submit one or more responsive data records that may provide information for use in determining a validity of the proposed incident-related data record. Validator nodes hosted by external agencies may submit validation responses relative to a validity of the proposed incident-related data record. The system may determine that the proposed data record is valid. Based a consensus algorithm, the system may responsively append the proposed data record or an indication of validity to the distributed ledger or to a different distributed ledger.

Abstract: Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

Abstract: Utilizing a computing device to detect and respond to emotion in dialog systems. The computing device receives a dialog structure comprising a plurality of dialog nodes. The computing device determines a node emotion level for each of the dialog nodes in the dialog structure based on analysis of one or more intents of each of the dialog nodes in the dialog structure. The computing device determines emotional hotspot nodes in the dialog structure, the node emotion level for each of the emotional hotspot nodes exceeding an emotional threshold. The computing device generates one or more responses modifying the node emotion level of each of the emotional hotspot nodes.

Abstract: Bleach catalyst detergent compositions are provided. The compositions are suitable for use with additional detergent and/or bleaching compositions while providing bleach catalysts within a detergent composition. The detergent compositions are free of anionic surfactant, are highly aqueous and have a pH of less than 6. Methods of use for cleaning are disclosed.

Abstract: Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.

Abstract: An embodiment of the invention may include a method, computer program product and system for redirecting data within a network. The embodiment may include receiving data for aggregation. The received data originates from one or more computing devices and flows through one or more edge devices. The received data comprises associated metadata. The embodiment may include identifying a topology for the received data based on the associated metadata. The embodiment may include determining whether the received data can be aggregated at an earlier edge device. The embodiment may include determining an aggregation location for subsequent data. The subsequent data is affiliated with the received data. The embodiment may include determining a network route for utilization by the subsequent data. The embodiment may include propagating the determined aggregation location and network route. The embodiment may include transmitting the received data to the determined aggregation location.

Abstract: Nonnaturally occurring host cells altered to increase their ability to transfer genetic molecules into the host cells as compared to an unaltered host cell are provided. Also provided are methods for identifying endogenous loci of a host cell which inhibit transformation efficiency and/or electroporation of genetic molecules into the cell as well as methods for producing nonnaturally occurring host cells with enhanced transformation efficiency and/or the modified ability to allow for genomic integration of an exogenous DNA sequence via electroporation. Methods for producing biochemicals and products produced with the nonnaturally occurring host cells are also provided. In particular, a host Cupriavidus necator cell is provided in which a chromosomal gene encoding a restriction endonuclease has been disrupted, leading to an increase in transformation efficiency.

Abstract: A system for implementing strobing of existing vehicle hazard lights including an interface to a vehicle wiring harness configured to receive input to an existing vehicle flasher module, and a strobing circuit that responds to an activation signal from the vehicle wiring harness that is indicative of a hazard flasher deployment event by producing an electrical output through the interface to the vehicle wiring harness that causes a strobing of existing vehicle hazard lamps.

Abstract: Embodiments of the present disclosure generally relate to protective coatings on an aerospace component and methods for depositing the protective coatings. In one or more embodiments, a method for depositing a coating on an aerospace component includes exposing an aerospace component to a first precursor and a first reactant to form a first deposited layer on a surface of the aerospace component by a chemical vapor deposition (CVD) process or a first atomic layer deposition (ALD) process and exposing the aerospace component to a second precursor and a second reactant to form a second deposited layer on the first deposited layer by a second ALD process, where the first deposited layer and the second deposited layer have different compositions from each other.

Abstract: Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: (I), (II) where the definitions of the variables are provided herein.

Abstract: Methods and systems are provided for generating training data for training a classifier to assign nodes of a taxonomy graph to items based on item descriptions. Each node has a label. For each item, the system identifies for that item one or more candidate paths within the taxonomy graph that are relevant to that item. The system identifies the candidate paths based on content of the item description of that item matching labels of nodes. A candidate path is a sequence of nodes starting a root node of the taxonomy graph. For each identified candidate path, the system labels the item description with the candidate path equivalently with leaf node or label of the leaf node. The labeled item descriptions compose the training data for training the classifier.

Abstract: A content replacement system and method for simultaneously updating a plurality of images of visual designs on an electronic display of an electronic device using synchronized client- and server-side visual design object models by representing visual objects in visual designs using a keyed attribute and associated attribute value comprising a visual object specification.

Abstract: A fenestration assembly includes a sash, a frame surrounding the sash, and at least one screen assembly. The sash includes at least one magnet. The sash is slideably engaged with the frame. The at least one screen assembly includes a roller assembly, a control bar, and screen material attached to the roller assembly and the control bar. The roller assembly is substantially hidden from view. The control bar includes a ferromagnetic material. The screen assembly is configured to apply tension to the screen material to wind the screen material around the roller assembly and to permit the screen material to unwind from the roller assembly under a tension applied to move the control bar away from the roller assembly. The control bar automatically engages the at least one magnet of the sash when the sash is in the closed configuration to attach the control bar to the sash.

Abstract: A sensor package includes at least one conductive trace providing a voltage common and a base supporting the at least one conductive trace. A conductive extension extends from the base so as to contact a conductor of an insulated conductor when the sensor package is mounted on an insulator of the insulated conductor and thereby provide an electrical connection between the conductive trace providing the voltage common and the conductor.

Abstract: This technology relates to a condensation reduction system for a sensor. The system may comprise a sensor cover, wherein the sensor cover is configured to house one or more sensor components, a flexible, external chamber, and a conduit. The external chamber may be communicably coupled to an interior of the sensor cover via the conduit configured such that during an increase of pressure of gas within the sensor cover the gas flows to the external chamber via the conduit and during a decrease in the pressure of gas within the sensor cover the gas flows from the external chamber to the sensor cover via the conduit.

Abstract: A first display device and method are provided for accelerating the coarse relocalization process of the first display device by generating a session-specific identifier and sending it to a second display device, which transmits the identifier to a cloud service, which returns at least a portion of a map data set corresponding to the identifier. The returned map data set is then stitched into the local map data of the first display device to create an integrated map, which is used to render one or a plurality of holograms. The first display device may comprise a processor, a memory operatively coupled to the processor, and a fingerprint program stored in the memory and executed by the processor.

Abstract: The human body is mediated by a large number of chemicals and chemical processes where imbalances can result in an abnormal condition that affects part or all of the human body. Amongst these conditions are hair loss and male impotence or erectile dysfunction, both of which can have psychological consequences for the patient and others as they can be tied to relationship difficulties and self-image. 5?-reductase Type II inhibitors prevent DHT production and reduce androgen activity in key tissues such as prostate and scalp. Similarly, an inhibitor of cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) can lead to improved vasodilation and blood flow. It would be beneficial to provide patients with either of these treatments within a topical cream form allowing localized targeted delivery.

Abstract: A gas distribution assembly for applying a coating on an interior of a plurality of components includes a support with a plurality of component cavities formed within the support. Each component cavity corresponds to a respective component to fluidly couple with an interior of the respective component. A first gas source flow line is fluidly coupled with each of the component cavities to provide a first gas from a first gas source to each of the component cavities, and a second gas source flow line is fluidly coupled with each of the component cavities to provide a second gas from a second gas source to each of the component cavities.