Patents by Inventor Jonathan Joseph Powell

Jonathan Joseph Powell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11406664
    Abstract: The use of ferric maltol compositions for the treatment or prevention of cancer and tumours is disclosed, in particular for the treatment or prevention of gastrointestinal cancers or gastrointestinal tumours, such as large bowel (colorectal), small bowel or upper gastrointestinal cancers.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: August 9, 2022
    Assignee: SHIELD TX (UK) LIMITED
    Inventors: Jonathan Joseph Powell, Dora I. A. Pereira
  • Patent number: 11267836
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, are described in which maltolis reacted with a ligand modified ferric hydroxide and/or a ligand coated ferric hydroxide.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: March 8, 2022
    Assignee: SHIELD TX (UK) LIMITED
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria
  • Publication number: 20210338710
    Abstract: Compositions comprising silica particles having a mean size by standard particle sizing of between 0.5 nm and 20 nm are described for used in activating lymphocytes in culture or in whole blood.
    Type: Application
    Filed: April 19, 2021
    Publication date: November 4, 2021
    Applicant: United Kingdom Research and Innovation
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Rachel Elaine Hewitt, Bradley Michael Vis, Carlos Bastos
  • Patent number: 11155529
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, from elemental iron, and ferric maltol compositions produced by these methods and their uses are described.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: October 26, 2021
    Assignee: SHIELD TX (UK) LIMITED
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria
  • Publication number: 20210145866
    Abstract: Stabilised and aquated polymeric silicate compositions are described in which the compositions are poorly condensed compositions in which the silicates are resorbable and are capable of undergoing efficient dissolution to provide bioavailable soluble silicic acid. In particular, stabilised and aquated polymeric silicates are described that are capable of intravenous delivery, useful in the treatment of cancer or systemic infection, or for topical administration, e.g. in the form of a solid or semi-solid ointment useful in the treatment of wounds or the prevention of bacterial infection.
    Type: Application
    Filed: December 15, 2020
    Publication date: May 20, 2021
    Applicant: United Kingdom Research and Innovation
    Inventors: Carlos André Passos BASTOS, Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA, Bradley Michael VIS
  • Patent number: 11007217
    Abstract: Compositions comprising silica particles having a mean size by standard particle sizing of between 0.5 nm and 20 nm are described for used in activating lymphocytes in culture or in whole blood.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: May 18, 2021
    Assignee: United Kingdom Research and Innovation
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Rachel Elaine Hewitt, Bradley Michael Vis, Carlos Bastos
  • Patent number: 11000502
    Abstract: Copper based antibacterial agents are described based on amphiphilic copper complexes formed between copper and hydroxypyrones, such as maltol. In further aspects, the present invention relates to PEG based-ointments showing that they are particularly effective for topical delivery of amphiphilic complexes of copper. In particular, PEG ointments were shown to limit bacterial growth, even when in the absence of copper agent. However, this bacteriostatic effect is shown herein to become a true biocidal effect when copper hydroxypyrones are added to the PEG.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: May 11, 2021
    Assignee: United Kingdom Research and Innovation
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Carlos Andre Passos Bastos
  • Patent number: 10898511
    Abstract: Stabilised and aquated polymeric silicate compositions are described in which the compositions are poorly condensed compositions in which the silicates are resorbable and are capable of undergoing efficient dissolution to provide bioavailable soluble silicic acid. In particular, stabilised and aquated polymeric silicates are described that are capable of intravenous delivery, useful in the treatment of cancer or systemic infection, or for topical administration, e.g. in the form of a solid or semi-solid ointment useful in the treatment of wounds or the prevention of bacterial infection.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: January 26, 2021
    Assignee: United Kingdom Research and Innovation
    Inventors: Carlos André Passos Bastos, Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Bradley Michael Vis
  • Publication number: 20200306293
    Abstract: The use of ferric maltol compositions for the treatment or prevention of cancer and tumours is disclosed, in particular for the treatment or prevention of gastrointestinal cancers or gastrointestinal tumours, such as large bowel (colorectal), small bowel or upper gastrointestinal cancers.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 1, 2020
    Inventors: Jonathan Joseph POWELL, Dora I.A. PEREIRA
  • Publication number: 20200308130
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, from elemental iron, and ferric maltol compositions produced by these methods and their uses are described.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 1, 2020
    Inventors: Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA
  • Patent number: 10722459
    Abstract: Processes for recovering colloids of carboxylate ligand modified ferric iron hydroxide materials such as IHAT (Iron Hydroxide Adipate Tartrate) are described based on the use of water miscible non-aqueous solvents, such as ethanol, methanol and acetone. The processes produce materials with advantageous properties such as improved bioavailability, reduced aggregation and/or agglomeration and/or increased iron content.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: July 28, 2020
    Assignee: United Kingdom Research and Innovation
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria
  • Publication number: 20200155453
    Abstract: Processes for recovering colloids of carboxylate ligand modified ferric iron hydroxide materials such as IHAT (Iron Hydroxide Adipate Tartrate) are described based on the use of water miscible non-aqueous solvents, such as ethanol, methanol and acetone. The processes produce materials with advantageous properties such as improved bioavailability, reduced aggregation and/or agglomeration and/or increased iron content.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 21, 2020
    Applicant: Medical Research Council
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria
  • Patent number: 10596122
    Abstract: Amorphous magnesium-substituted calcium, phosphate compositions and their medical uses are described, in particular for use in delivering cargo materials, such as cargo molecules or cargo nanoparticles contained in pores of the amorphous magnesium-substituted calcium phosphate to cells of the immune system, for example as therapeutic approaches for the treatment of inflammatory bowel diseases, and in particular Crohn's disease, autoimmune diseases, allergy and for therapeutic vaccination.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: March 24, 2020
    Assignee: Medical Research Council
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodriguez Faria, Laetitia Pele, Rachel Hewitt, Emma Thomas-McKay
  • Publication number: 20190380996
    Abstract: Copper based antibacterial agents are described based on amphiphilic copper complexes formed between copper and hydroxypyrones, such as maltol. In further aspects, the present invention relates to PEG based-ointments showing that they are particularly effective for topical delivery of amphiphilic complexes of copper. In particular, PEG ointments were shown to limit bacterial growth, even when in the absence of copper agent. However, this bacteriostatic effect is shown herein to become a true biocidal effect when copper hydroxypyrones are added to the PEG.
    Type: Application
    Filed: February 6, 2018
    Publication date: December 19, 2019
    Applicant: United Kingdom Research and Innovation
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Carlos Andre Passos Bastos
  • Patent number: 10508094
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, from ferrous hydroxides, are described, as well as ferric maltol compositions produced by these methods and their uses.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: December 17, 2019
    Assignee: SHIELD TX (UK) LIMITED
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria
  • Publication number: 20190224233
    Abstract: Stabilised and aquated polymeric silicate compositions are described in which the compositions are poorly condensed compositions in which the silicates are resorbable and are capable of undergoing efficient dissolution to provide bioavailable soluble silicic acid. In particular, stabilised and aquated polymeric silicates are described that are capable of intravenous delivery, useful in the treatment of cancer or systemic infection, or for topical administration, e.g. in the form of a solid or semi-solid ointment useful in the treatment of wounds or the prevention of bacterial infection.
    Type: Application
    Filed: October 24, 2018
    Publication date: July 25, 2019
    Inventors: Carlos André Passos BASTOS, Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA, Bradley Michael VIS
  • Publication number: 20190192555
    Abstract: Compositions comprising silica particles having a mean size by standard particle sizing of between 0.5 nm and 20 nm are described for used in activating lymphocytes in culture or in whole blood.
    Type: Application
    Filed: August 9, 2017
    Publication date: June 27, 2019
    Inventors: Jonathan Joseph Powell, Nuno Jorge Rodrigues Faria, Rachel Elaine Hewitt, Bradley Michael Vis, Carlos Bastos
  • Publication number: 20190127344
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, from ferrous hydroxides, are described, as well as ferric maltol compositions produced by these methods and their uses.
    Type: Application
    Filed: March 31, 2017
    Publication date: May 2, 2019
    Inventors: Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA
  • Publication number: 20190106449
    Abstract: Methods for producing ferric maltol compositions, such as ferric trimaltol, are described in which maltolis reacted with a ligand modified ferric hydroxide and/or a ligand coated ferric hydroxide.
    Type: Application
    Filed: March 31, 2017
    Publication date: April 11, 2019
    Inventors: Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA
  • Publication number: 20180271784
    Abstract: Processes for recovering colloids of carboxylate ligand modified ferric iron hydroxide materials such as IHAT (Iron Hydroxide Adipate Tartrate) are described based on the use of water miscible non-aqueous solvents, such as ethanol, methanol and acetone. The processes produce materials with advantageous properties such as improved bioavailability, reduced aggregation and/or agglomeration and/or increased iron content.
    Type: Application
    Filed: October 7, 2016
    Publication date: September 27, 2018
    Applicant: Medical Research Council
    Inventors: Jonathan Joseph POWELL, Nuno Jorge Rodrigues FARIA