Patents by Inventor Jonathan Macferran Hughes

Jonathan Macferran Hughes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-(?-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use
    Patent number: 9102830
    Abstract: The present invention provides biodegradable, biocompatible bis-(?-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 11, 2015
    Assignee: MEDIVAS, LLC
    Inventors: Zaza D. Gomurashvili, Jonathan Macferran Hughes, Jie Da, Huashi Zhang
  • Bis-(?-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use
    Patent number: 8445007
    Abstract: The present invention provides biodegradable, biocompatible bis-(?-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: May 21, 2013
    Assignee: Medivas, LLC
    Inventors: Zaza D. Gomurashvili, Jonathan Macferran Hughes, Jie Da, Huashi Zhang
  • Bis-(Alpha-Amino)-Diol-Diester-Containing Poly (Ester Amide) and Poly (Ester Urethane) Compositions and Methods of Use
    Publication number: 20080299174
    Abstract: The present invention provides biodegradable, biocompatible bis-(?-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
    Type: Application
    Filed: September 22, 2006
    Publication date: December 4, 2008
    Inventors: Zaza D. Gomurashvili, Jonathan Macferran Hughes, Jie Da, Huashi Zhang