Patents by Inventor Joo-Sun Son

Joo-Sun Son has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass production of paclitaxel by changing the temperature of the medium during the plant cell culture
    Patent number: 6589765
    Abstract: The present invention relate to a method to increase the production level of paclitaxel by changing the temperature during the plant cell culture. According to the present invention, the production of the paclitaxel comprises the following procedure: (i) cultivating the Taxus genus plant cells in a medium at ca. 20 to 25° C.; and (ii) when growth of the plant cells has progressed sufficiently, changing the cultivation temperature to ca. 26 to 32° C. to continue the culture. The present invention comprises also the method of increasing the paclitaxel production by inoculating the cells at a high initial concentration and by increasing the saccharide concentration in the medium: According to the present invention, paclitaxel can be mass-produced conveniently and therefore has an industrial application.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: July 8, 2003
    Assignee: Samyang Genex Corporation
    Inventors: Ho-Joon Choi, Hyung-Kyoon Choi, Sang-Ic Kim, Jeong-Hwan Yun, Joo-Sun Son, Moon-Seok Chang, Eunsoo Choi, Hong-Rak Kim, Seung-Suh Hong, Hyun-Soo Lee