Patents by Inventor Jorge Garcia

Jorge Garcia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
    Publication number: 20210371429
    Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: February 23, 2021
    Publication date: December 2, 2021
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, John William Giraldes, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Bakary-Barry Toure, Sarah Williams
  • Dynamically enabling tiling in 3D workloads
    Patent number: 11176736
    Abstract: Methods, systems and apparatuses may provide for technology that determines the size of a graphics primitive, renders pixels associated with the graphics primitive on a per tile basis if the size exceeds a threshold, and renders the pixels associated with the graphics primitive in a mesh order if the size does not exceed the threshold. In one example, the technology discards state data associated with the graphics primitive in response to a completion of rendering the pixels associated with the graphics primitive in the mesh order.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: November 16, 2021
    Assignee: Intel Corporation
    Inventors: Justin DeCell, Saurabh Sharma, Subramaniam Maiyuran, Raghavendra Miyar, Jorge Garcia Pabon
  • METHOD FOR THE IDENTIFICATION OF CARDIAC FIBRILLATION DRIVERS AND/OR THE FOOTPRINT OF ROTATIONAL ACTIVATIONS USING SINGLE OPTICAL OR ELECTRICAL SIGNALS WITHOUT REQUIRING PANORAMIC SIMULTANEOUS ACQUISITION
    Publication number: 20210338137
    Abstract: This invention relates to an ex vivo use of the instantaneous frequency modulation (iFM) signal of cardiac activations and to an ex vivo use of the instantaneous amplitude modulation (iAM) signal obtained from the sequence of amplitude excursions of said activations for detecting ‘driver’ or ‘high-hierarchy’ regions and/or the cardiac spots that display the footprint of rotational activations in the heart of a subject with cardiac fibrillation without requiring panoramic simultaneous acquisition.
    Type: Application
    Filed: October 11, 2019
    Publication date: November 4, 2021
    Inventors: Jorge GARCÍA QUINTANILLA, David FILGUEIRAS RAMA, Nicasio PÉREZ CASTELLANO, Julián PÉREZ-VILLACASTÍN DOMÍNGUEZ
  • Plenoptic ocular device
    Publication number: 20210325658
    Abstract: The invention relates to a plenoptic ocular device intended to be coupled in an ocular port of an optical instrument configured to generate a real image of a sample on a focal plane situated in a region close to said ocular port, said plenoptic ocular device being configured to capture said real image, generate a set of elemental images and send them to recording means with spatial discretisation which in turn comprises communication means configured to transmit the set of elemental images to external image processing means.
    Type: Application
    Filed: August 8, 2019
    Publication date: October 21, 2021
    Inventors: Manuel Martinez Corral, Genaro Saavedra Tortosa, Gabriele Scrofani, Angel Tolosa Ruiz, Jorge Garcia Sucerquia
  • COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
    Publication number: 20210309663
    Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, Y3, Y4 R1, R2, R4a, R4b, R5a, R5b, R6a and R6b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: March 3, 2021
    Publication date: October 7, 2021
    Inventors: Jeffrey T. Bagdanoff, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, Mitsunori Kato, Matthew J. LaMarche, Patrick James Sarver, Michael Shultz, Troy Douglas Smith, Sarah Williams
  • Systems and methods for data protection
    Patent number: 11138475
    Abstract: Systems and methods for data protection are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for providing data protection may include: (1) receiving a plurality of data classification rules; (2) receiving end user data classification from end user software; (3) receiving developer data classification from SDLC software; (4) generating a data inventory; and (5) applying at least one data protection to the data inventory based on the data classification rules, the end user data classification, and the developer data classification.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: October 5, 2021
    Assignee: JPMORGAN CHASE BANK, N.A.
    Inventors: Matthew Jesse Collins, David MacFarlane, Sean Thomas Kornish, Jorge Garcia Reyero, Philip Harvey
  • COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
    Publication number: 20210300919
    Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: December 22, 2020
    Publication date: September 30, 2021
    Inventors: Zhuoliang CHEN, Jorge Garcia FORTANET, Rajesh KARKI, Matthew J. LAMARCHE, Dyuti MAJUMDAR, Lawrence Blas PEREZ, Martin SENDZIK, Troy Douglas SMITH, Fan YANG, Bing YU
  • REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF
    Publication number: 20210292477
    Abstract: A method of preparing a polycarbonate composition, including: melt polymerizing in a polymerization unit a dihydroxy compound with a diaryl carbonate and removing a stream of color inducing species containing an isopropenyl phenyl-containing group from the polymerization unit, to form a polycarbonate composition, wherein the polycarbonate has a color inducing species containing an isopropenyl phenyl-containing group level below 170 ppm is provided.
    Type: Application
    Filed: January 16, 2018
    Publication date: September 23, 2021
    Inventors: Aaron David Bojarski, Jorge A. Garcia Agudo
  • METHODS AND COMPOSITIONS FOR GENETICALLY MANIPULATING GENES AND CELLS
    Publication number: 20210284979
    Abstract: This disclosure provides methods and compositions for genetically manipulating genes and cells.
    Type: Application
    Filed: March 1, 2021
    Publication date: September 16, 2021
    Inventors: Tzumin Lee, Jorge Garcia Marques, Hui-Min Chen
  • DYNAMICALLY ENABLING TILING IN 3D WORKLOADS
    Publication number: 20210217235
    Abstract: Methods, systems and apparatuses may provide for technology that determines the size of a graphics primitive, renders pixels associated with the graphics primitive on a per tile basis if the size exceeds a threshold, and renders the pixels associated with the graphics primitive in a mesh order if the size does not exceed the threshold. In one example, the technology discards state data associated with the graphics primitive in response to a completion of rendering the pixels associated with the graphics primitive in the mesh order.
    Type: Application
    Filed: January 21, 2021
    Publication date: July 15, 2021
    Inventors: Justin DeCell, Saurabh Sharma, Subramaniam Maiyuran, Raghavendra Miyar, Jorge Garcia Pabon
  • Systems and methods for dynamic application level encryption
    Patent number: 11032320
    Abstract: Systems and methods for dynamic application level encryption are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for dynamic application level encryption include: (1) receiving a plurality of data classification rules; (2) classifying data using the data classification rules; (3) identifying at least one protection option of a plurality of protection options for protecting the data in at least a rest state, an in-transit state, and an in-memory state; and (4) applying the at least one protection option to the data at rest.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: June 8, 2021
    Assignee: JPMorgan Chase Bank, N.A.
    Inventors: Jorge Garcia Reyero, Marco C. Pineda, Jody Spearing
  • Compounds and compositions for inhibiting the activity of SHP2
    Patent number: 10975080
    Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, Y3, Y4 R1, R2, R4a, R4b, R5a, R5b, R6a and R6b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: April 13, 2021
    Assignee: NOVARTIS AG
    Inventors: Jeffrey T. Bagdanoff, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, Mitsunori Kato, Matthew J. LaMarche, Patrick James Sarver, Michael Shultz, Troy Douglas Smith, Sarah Williams
  • N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2
    Patent number: 10968235
    Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: April 6, 2021
    Assignee: NOVARTIS AG
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, John William Giraldes, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Bakary-Barry Toure, Sarah Williams
  • Compounds and compositions for inhibiting the activity of SHP2
    Patent number: 10934285
    Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: March 2, 2021
    Assignee: NOVARTIS AG
    Inventors: Zhuoliang Chen, Jorge Garcia Fortanet, Rajesh Karki, Matthew J. Lamarche, Dyuti Majumdar, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Fan Yang, Bing Yu
  • Dynamically enabling tiling in 3D workloads
    Patent number: 10916052
    Abstract: Methods, systems and apparatuses may provide for technology that determines the size of a graphics primitive, renders pixels associated with the graphics primitive on a per tile basis if the size exceeds a threshold, and renders the pixels associated with the graphics primitive in a mesh order if the size does not exceed the threshold. In one example, the technology discards state data associated with the graphics primitive in response to a completion of rendering the pixels associated with the graphics primitive in the mesh order.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: February 9, 2021
    Assignee: Intel Corporation
    Inventors: Justin DeCell, Saurabh Sharma, Subramaniam Maiyuran, Raghavendra Miyar, Jorge Garcia Pabon
  • 1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVES AND COMPOSITIONS THEREOF FOR INHIBITING THE ACTIVITY OF SHP2
    Publication number: 20200369643
    Abstract: The present invention relates to compounds of formula I: in which m, Y1, Y2, Y3, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a and R5b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 26, 2020
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Jorge Garcia Fortanet, Denise Grunenfelder, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Travis Matthew Stams, Sarah Williams
  • DYNAMICALLY ENABLING TILING IN 3D WORKLOADS
    Publication number: 20200342662
    Abstract: Methods, systems and apparatuses may provide for technology that determines the size of a graphics primitive, renders pixels associated with the graphics primitive on a per tile basis if the size exceeds a threshold, and renders the pixels associated with the graphics primitive in a mesh order if the size does not exceed the threshold. In one example, the technology discards state data associated with the graphics primitive in response to a completion of rendering the pixels associated with the graphics primitive in the mesh order.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 29, 2020
    Inventors: Justin DeCell, Saurabh Sharma, Subramaniam Maiyuran, Raghavendra Miyar, Jorge Garcia Pabon
  • 1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2
    Patent number: 10774065
    Abstract: The present invention relates to compounds of formula I: in which m, Y1, Y2, Y3, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a and R5b are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: September 15, 2020
    Assignee: NOVARTIS AG
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Jorge Garcia Fortanet, Denise Grunenfelder, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Travis Matthew Stams, Sarah Williams
  • SYSTEMS AND METHODS FOR DATA PROTECTION
    Publication number: 20200279139
    Abstract: Systems and methods for data protection are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for providing data protection may include: (1) receiving a plurality of data classification rules; (2) receiving end user data classification from end user software; (3) receiving developer data classification from SDLC software; (4) generating a data inventory; and (5) applying at least one data protection to the data inventory based on the data classification rules, the end user data classification, and the developer data classification.
    Type: Application
    Filed: March 1, 2019
    Publication date: September 3, 2020
    Inventors: Matthew Jesse Collins, David MacFarlane, Sean Thomas Kornish, Jorge Garcia Reyero, Philip Harvey
  • N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
    Publication number: 20200181168
    Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
    Type: Application
    Filed: May 21, 2019
    Publication date: June 11, 2020
    Inventors: Christine Hiu-Tung Chen, Zhuoliang Chen, Michael Dore, Jorge Garcia Fortanet, John William Giraldes, Rajesh Karki, Mitsunori Kato, Matthew J. LaMarche, Lawrence Blas Perez, Martin Sendzik, Troy Douglas Smith, Bakary-Barry Toure, Sarah Williams