Patents by Inventor Joseph A. Fix

Joseph A. Fix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tablets incorporating isoflavone plant extracts and methods of manufacturing them
    Patent number: 6413546
    Abstract: The invention is directed to novel tablets comprising isoflavone-containing plant extract and water-insoluble polysaccharides, and methods of manufacturing them.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: July 2, 2002
    Assignees: Indena, S.p.A., Johnson & Johnson Consumer Companies, Inc.
    Inventors: Min Michael He, Fang-Yu Liu, Joseph A. Fix, Martin Link, Maria L. Kang, Ezio Bombardelli
  • Automated focused microwave sample digestion system
    Patent number: 6111238
    Abstract: An automated microwave sample digestion system is disclosed in which a focused microwave digestion system is operated under computer control in association with a computer controlled robotic positioning system such that sample tubes containing samples to be digested are loaded and unloaded into and out from the cooking cavities of the microwave digestion oven in a preprogrammed manner in order to both increase the efficiency of the processing of samples as well as to produce consistent operating conditions for each sample being digested. An additional pump and syringe line is provided for both washing the tube condenser utilized during the digestion process as well as for diluting the digested sample.
    Type: Grant
    Filed: March 4, 1998
    Date of Patent: August 29, 2000
    Assignee: R. J. Reynolds Tobacco Company
    Inventors: Robert Joseph Fix, Sr., Jannell Mills Rowe, Samuel Mark DeBusk, Bain Clifford McConnell, John Larkin Nelson, Nancy Carol Huettel
  • Enhancment of absorption of drugs from gastrointestinal tract using choline ester salts
    Patent number: 4973579
    Abstract: Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.
    Type: Grant
    Filed: February 16, 1989
    Date of Patent: November 27, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix
  • Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
    Patent number: 4963556
    Abstract: Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.
    Type: Grant
    Filed: April 20, 1989
    Date of Patent: October 16, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix, A. J. Repta
  • Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments
    Patent number: 4963525
    Abstract: Acylcarnitine used as a nasal, buccal, sublingual and vaginal drug absorption enhancing vehicle for poorly absorbed drugs.
    Type: Grant
    Filed: May 16, 1989
    Date of Patent: October 16, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix, A. J. Repta
  • Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments
    Patent number: 4847298
    Abstract: Acylcarnitine used as a nasal, buccal, sublingual and vaginal drug absorption enhancing vehicle for poorly absorbed drugs.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: July 11, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix, A. J. Repta
  • Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
    Patent number: 4835138
    Abstract: Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.
    Type: Grant
    Filed: May 18, 1987
    Date of Patent: May 30, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, A. J. Repta, Joseph A. Fix
  • Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts
    Patent number: 4822773
    Abstract: Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.
    Type: Grant
    Filed: December 20, 1987
    Date of Patent: April 18, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix
  • Novel lysine esters used as absorption
    Patent number: 4749694
    Abstract: Novel lysine esters used as absorption enhancing agents for gastrointestinally and rectally administered drugs. Also provided are processes for preparation of said lysine ester compounds as well as pharmaceutical formulations and methods for their use as absorption enhancing agents.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: June 7, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Joseph A. Fix, Stefano A. Pogany
  • Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments
    Patent number: 4731360
    Abstract: Acylcarnitine used as a nasal, buccal, sublingual and vaginal drug absorption enhancing vehicle for poorly absorbed drugs.
    Type: Grant
    Filed: August 16, 1985
    Date of Patent: March 15, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, A. J. Repta, Joseph A. Fix
  • Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts
    Patent number: 4729989
    Abstract: Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.
    Type: Grant
    Filed: June 28, 1985
    Date of Patent: March 8, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix
  • Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
    Patent number: 4692441
    Abstract: Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.
    Type: Grant
    Filed: August 16, 1985
    Date of Patent: September 8, 1987
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, A. J. Repta, Joseph A. Fix
  • Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines
    Patent number: 4537772
    Abstract: Acylcarnitines used as drug absorption enhancing agents for orally and rectally administered drugs.
    Type: Grant
    Filed: May 2, 1984
    Date of Patent: August 27, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix
  • .alpha.-Keto aldehydes as enhancing agents of gastro-intestinal drug absorption
    Patent number: 4440740
    Abstract: A method and drug form enhancing the absorption of a rectally or orally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally and orally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the gastrointestinal area and an .alpha.-keto aldehyde or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when administering the drug form to warm blooded animals.
    Type: Grant
    Filed: April 26, 1982
    Date of Patent: April 3, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Joseph A. Fix, Stefano A. Pogany
  • Adjuvants for rectal delivery of drug
    Patent number: 4425337
    Abstract: A method and drug form enhancing the rate of absorption of a rectally administered drug from the rectal compartment into the blood stream of a warm blooded animal. The method includes the steps of preparing a drug form capable of being rectally administered. The drug form comprises a therapeutically effective unit dosage amount of a selected drug of the type which is capable of being absorbed into the blood stream from the rectal compartment and phenothiazines or salts thereof being present in the drug form in a sufficient amount to be effective in enhancing the drug absorption rate, when rectally administering the drug form to warm blooded animals.
    Type: Grant
    Filed: December 30, 1981
    Date of Patent: January 10, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Joseph A. Fix