Abstract: The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

Abstract: A method of improving the appearance of skin, involves topically administering to a subject in need thereof a botanical antioxidant composition having a botanical antioxidant extract blend with: (a) at least one hydroxycinnamic acid, and (b) a camellia sinesis, vitis vinifera, euterpe oleracea, curcuma longa, and/or theobroma cacao extract, wherein the composition is in cream, lotion, solution, serum, anhydrous preparation, emulsion, microemulsion, multiple emulsion, gel, solid stick, ointment, dry powder, spray, or aerosol form.

Abstract: A method of improving the appearance of skin, involves topically administering to a subject in need thereof a botanical antioxidant composition having a botanical antioxidant extract blend with: (a) at least one hydroxycinnamic acid, and (b) a camellia sinesis, vitis vinifera, euterpe oleracea, curcuma longa, and/or theobroma cacao extract, wherein the composition is in cream, lotion, solution, serum, anhydrous preparation, emulsion, microemulsion, multiple emulsion, gel, solid stick, ointment, dry powder, spray, or aerosol form.

Abstract: A botanical antioxidant composition has a botanical antioxidant extract blend with at least 50 wt. % of the blend having one or more hydroxycinnamic acid, and: a first component comprising a camellia sinesis extract, a vitis vinifera extract, a euterpe oleracea extract, a curcuma longa extract, or a theobroma cacao extract; and a second component, different from the first component, comprising the camellia sinesis extract, the vitis vinifera extract, the euterpe oleracea extract, the curcuma longa extract, or the theobroma cacao extract; wherein the composition is a cosmetic or dermatological formulation in a cream, lotion, solution, serum, anhydrous preparation, emulsion, microemulsion, multiple emulsion, gel, solid stick, ointment, dry powder, spray, or aerosol form.

Abstract: A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.

Abstract: A composition having an sunscreen agent, an antioxidant, and a DNA repair enzyme provides a beneficial and/or synergistically improved effect in reducing mutagenic formations, particularly in topically applied formulations.

Abstract: The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

Abstract: A botanical antioxidant composition includes a botanical antioxidant extract blend including a first antioxidant botanical extract including at least one hydroxycinnamic acid, and at least one additional antioxidant botanical extracts including at least one antioxidant selected from the group consisting of vitamins, stilbenoids, curcumininoids, tannins, flavones, flavonols, flavan-3-ols, flavanones, anthocyanidins, anthocyanins, isoflavones, flavanonols, proanthocyanidins, dihydroxybenzoic acids, and pyridine alkaloids.