Patents by Inventor Joseph David Santangelo

Joseph David Santangelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuated microorganisms for the treatment of infection
    Patent number: 6756042
    Abstract: The present invention pertains to a Salmonella microorganism having an attenuating mutation which disrupts the expression of a gene located within the Spi2 pathogenicity island, and an auxotrophic mutation. The microorganism therefore has a double mutation which helps prevent reactivity of the microorganism while maintaining the effectiveness of the microorganism to elicit an immune response. The present invention also pertains to vaccine compositions and methods for treating and preventing a Salmonella infection in a patient.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: June 29, 2004
    Assignee: Microscience, Ltd.
    Inventors: Robert Graham Feldman, Gordon Dougan, Joseph David Santangelo, David William Holden, Jacqueline Elizabeth Shea, Zoe Hindle
  • Genes and proteins, and their uses
    Publication number: 20040073000
    Abstract: A series of genes from Neisseria meningitidis are shown to encode products which are targets for immunisation. The identification of these genes therefore allows vaccines to be produced and other therapeutic products.
    Type: Application
    Filed: October 2, 2003
    Publication date: April 15, 2004
    Inventors: Jonathan Douglas Lane, Martin John Glenton Hughes, Joseph David Santangelo
  • Genes and proteins, and their use
    Publication number: 20030104000
    Abstract: A protein from Group B Streptococcus is shown to be an outer surface protein and is a useful target for antimicrobial therapy.
    Type: Application
    Filed: March 11, 2002
    Publication date: June 5, 2003
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Attenuated microorganisms for the treatment of infection
    Publication number: 20030059442
    Abstract: Double mutant Salmonella microorganisms help prevent reactivity of the microorganism while maintaining the effectiveness of the microorganism to elicit an immune response. Various specific combinations of mutants are beneficial.
    Type: Application
    Filed: September 23, 2002
    Publication date: March 27, 2003
    Inventors: Gordon Dougan, David William Holden, Joseph David Santangelo, Jacqueline Elizabeth Shea, Francis Richard Brennan