Patents by Inventor Joseph Dudash

Joseph Dudash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 8796313
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: August 5, 2014
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Joseph Dudash, Philip Rybczynski, Maud Urbanski, Amy Xiang, Roxanne Zeck, Xiaoyan Zhang, Yongzheng Zhang
  • Dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 7928246
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • DIHYDROISOINDOLONES AS ALLOSTERIC MODULATORS OF GLUCOKINASE
    Publication number: 20090202525
    Abstract: The present invention relates to compounds of Formula (1), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: April 15, 2009
    Publication date: August 13, 2009
    Inventors: Haiyan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 7531671
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: May 12, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang
  • Dihydroisoindolones As Allosteric Modulators Of Glucokinase
    Publication number: 20070099936
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: October 30, 2006
    Publication date: May 3, 2007
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang
  • Substituted Dihydroisoindolones As Allosteric Modulators of Glucokinase
    Publication number: 20070099930
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: October 30, 2006
    Publication date: May 3, 2007
    Inventors: Joseph Dudash, Philip Rybczynski, Maud Urbanski, Amy Xiang, Roxanne Zeck, Xiaoyan Zhang, Yongzheng Zhang
  • Quinoxalinones
    Publication number: 20050148586
    Abstract: The invention features quinoxalinones, pharmaceutical compositions containing them and methods of using them to treat, for example, diabetes.
    Type: Application
    Filed: December 22, 2004
    Publication date: July 7, 2005
    Inventors: Mary Beavers, Joseph Dudash, Yongzheng Zhang
  • Biologically active 4H-benzo [1,4] oxazin-3-ones
    Patent number: 6908908
    Abstract: The invention is directed to 4h-benzo[1,4]oxazin-3-ones useful as peroxisome proliferator activated receptor gamma (PPAR?) agonists or antagonists. Pharmaceutical compositions comprising compounds of the present invention and methods of treating conditions such as NIDDM and obesity are also disclosed.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: June 21, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Thomas P. Burris, Donald W. Combs, Philip J. Rybczynski, Joseph Dudash, Jr.
  • Biologically active 4H-benzo [1,4] oxazin-3-ones
    Publication number: 20030083329
    Abstract: The invention is directed to 4h-benzo[1,4]oxazin-3-ones useful as peroxisome proliferator activated receptor gamma (PPAR&ggr;) agonists or antagonists. Pharmaceutical compositions comprising compounds of the present invention and methods of treating conditions such as NIDDM and obesity are also disclosed.
    Type: Application
    Filed: November 21, 2001
    Publication date: May 1, 2003
    Inventors: Thomas P. Burris, Donald W. Combs, Philip J. Rybczynski, Joseph Dudash