Patents by Inventor Joseph F. Nabhan

Joseph F. Nabhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARRDC1-MEDIATED MICROVESICLES (ARMMS) AND USES THEREOF
    Publication number: 20210315814
    Abstract: The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated microvesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.
    Type: Application
    Filed: February 5, 2021
    Publication date: October 14, 2021
    Applicants: President and Fellows of Harvard College, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Quan Lu, Joseph F. Nabhan, Stanley N. Cohen
  • ARRDC1-mediated microvesicles (ARMMS) and uses thereof
    Patent number: 10945954
    Abstract: The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated microvesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: March 16, 2021
    Assignees: President and Fellows of Harvard College, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Quan Lu, Joseph F. Nabhan, Stanley N. Cohen
  • Modulators of Chromosome 9 Open Reading Frame 72 Gene Expression and Uses Thereof
    Publication number: 20200339638
    Abstract: The present disclosure provides compositions and methods for modulating transcription of mutant C9orf72 gene alleles in patients in need thereof, including patients having a C9orf72-related disease such as amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD).
    Type: Application
    Filed: April 23, 2020
    Publication date: October 29, 2020
    Applicant: Sangamo Therapeutics, Inc.
    Inventors: Joseph F. Nabhan, Amrutha Pattamatta, Mohammad Samie
  • ARRDC1-MEDIATED MICROVESICLES (ARMMS) AND USES THEREOF
    Publication number: 20180055768
    Abstract: The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated microvesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.
    Type: Application
    Filed: August 4, 2017
    Publication date: March 1, 2018
    Applicants: President and Fellows of Harvard College, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Quan Lu, Joseph F. Nabhan, Stanley N. Cohen
  • ARRDC1-mediated microvesicles (ARMMs) and uses thereof
    Patent number: 9737480
    Abstract: The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated micro vesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: August 22, 2017
    Assignees: President and Fellows of Harvard College, The Board of Trustees of the Leland Standford Junior University
    Inventors: Quan Lu, Joseph F. Nabhan, Stanley N. Cohen
  • ARRDC1-MEDIATED MICROVESICLES (ARMMS) AND USES THEREOF
    Publication number: 20150037421
    Abstract: The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated micro vesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.
    Type: Application
    Filed: February 6, 2013
    Publication date: February 5, 2015
    Applicants: President and Fellows of Harvard College, The Board of Trustees of the Leland Stanford JuniorUniversity
    Inventors: Quan Lu, Joseph F. Nabhan, Stanley N. Cohen