Patents by Inventor Joseph H. Gorman

Joseph H. Gorman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210153902
    Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state; wherein when at least a portion of the retrieval end of the inner sheath is transitioned to a compressed state following capture of the object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.
    Type: Application
    Filed: February 2, 2021
    Publication date: May 27, 2021
    Inventors: Matthew J Gillespie, Joseph H Gorman, III, Robert C Gorman, Mark Piper
  • Publication number: 20210093763
    Abstract: A method and device are provided for non-blood contact mechanically assisting an injured (e.g., infarcted) ventricle by coupling an inflatable bladder or other volume adjustable device to the injured ventricle and selectively inflating the bladder or increasing the size of the volume in systole to apply force against the injured ventricle and deflating the bladder or reducing the size of the volume in diastole to remove force against the injured ventricle. When no mechanical assistance is being provided to the injured ventricle, the inflatable bladder or volume adjustable device is preferably maintained at a predetermined pressure so as to selectively stiffen the injured tissue and alter ventricular geometry a desired amount.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 1, 2021
    Inventors: James J Pilla, Robert C Gorman, Joseph H Gorman, III
  • Patent number: 10939938
    Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state; wherein when at least a portion of the retrieval end of the inner sheath is transitioned to a compressed state following capture of the object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: March 9, 2021
    Assignees: The Trustees of the University of Pennsylvania, The Children's Hospital of Philadelphia
    Inventors: Matthew J. Gillespie, Joseph H. Gorman, III, Robert C. Gorman, Mark Piper
  • Publication number: 20200394798
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Application
    Filed: August 24, 2020
    Publication date: December 17, 2020
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, III, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang
  • Patent number: 10828409
    Abstract: A method and device are provided for non-blood contact mechanically assisting an injured (e.g., infarcted) ventricle by coupling an inflatable bladder or other volume adjustable device to the injured ventricle and selectively inflating the bladder or increasing the size of the volume in systole to apply force against the injured ventricle and deflating the bladder or reducing the size of the volume in diastole to remove force against the injured ventricle. When no mechanical assistance is being provided to the injured ventricle, the inflatable bladder or volume adjustable device is preferably maintained at a predetermined pressure so as to selectively stiffen the injured tissue and alter ventricular geometry a desired amount.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: November 10, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: James J Pilla, Robert C Gorman, Joseph H Gorman, III
  • Patent number: 10783631
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: September 22, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, III, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang
  • Patent number: 10588511
    Abstract: A retrospective reconstruction method uses cardiac self-gating for patients with severe arrhythmias. Self-gated myocardial systolic and diastolic motion is determined from low-spatial and high-temporal resolution images and then the MRI-dataset is retrospectively reconstructed to obtain high quality images. The method uses undersampled image reconstruction to obtain the low-spatial and high-temporal resolution images, including those of different beat morphologies. Processing of these images is utilized to generate a cardiac phase signal. This signal allows for arrhythmia detection and cardiac phase sorting. The cardiac phase signal allows for detection of end-systolic and diastolic events which allows for improved sampling efficiency. In the case of frequent and severe arrhythmia, the method utilizes data from the normal and interrupted beats to improve sampling and image quality.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: March 17, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Francisco Contijoch, Walter R. T. Witschey, Robert C. Gorman, Yuchi Han, Joseph H. Gorman, III
  • Publication number: 20200046495
    Abstract: The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.
    Type: Application
    Filed: October 18, 2019
    Publication date: February 13, 2020
    Inventors: Joseph H. Gorman, III, Robert C. Gorman, Matthew J. Gillespie
  • Publication number: 20190224395
    Abstract: A method and device are provided for non-blood contact mechanically assisting an injured (e.g., infarcted) ventricle by coupling an inflatable bladder or other volume adjustable device to the injured ventricle and selectively inflating the bladder or increasing the size of the volume in systole to apply force against the injured ventricle and deflating the bladder or reducing the size of the volume in diastole to remove force against the injured ventricle. When no mechanical assistance is being provided to the injured ventricle, the inflatable bladder or volume adjustable device is preferably maintained at a predetermined pressure so as to selectively stiffen the injured tissue and alter ventricular geometry a desired amount.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 25, 2019
    Inventors: James J. Pilla, Robert C. Gorman, Joseph H. Gorman, III
  • Publication number: 20190213737
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 11, 2019
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, III, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang
  • Publication number: 20190183647
    Abstract: An annuloplasty ring comprising an elongated curved member defining a ring-shape having an at rest size and shape to fit against the annulus of the mitral valve in a heart, the member having a substantial saddle shape wherein the annular height to width ratio is in the range of 5% to 50%.
    Type: Application
    Filed: August 21, 2018
    Publication date: June 20, 2019
    Inventors: Ivan S. Salgo, Joseph H. Gorman, III, Robert C. Gorman
  • Patent number: 10321988
    Abstract: A mitral valve prosthesis is percutaneously and/or transapically deployed in at least two stages. In a first stage, a mitral annular ring platform adapted for percutaneous delivery is delivered to and anchored in the mitral valve annulus. In the second stage, a valved-stent mitral valve prosthetic device adapted for percutaneously delivery is delivered to the mitral valve annulus for mounting in the mitral annular ring platform. This approach provides a consistent platform for accepting valved-stent mitral valve prosthetic devices from different vendors to be used.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: June 18, 2019
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Joseph H. Gorman, III, Robert C. Gorman, Matthew J. Gillespie
  • Patent number: 10235754
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: March 19, 2019
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang
  • Publication number: 20190038316
    Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state; wherein when at least a portion of the retrieval end of the inner sheath is transitioned to a compressed state following capture of the object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.
    Type: Application
    Filed: October 8, 2018
    Publication date: February 7, 2019
    Inventors: Matthew J. Gillespie, Joseph H. Gorman, III, Robert C. Gorman, Mark Piper
  • Publication number: 20180368977
    Abstract: A mitral valve prosthesis is percutaneously and/or transapically deployed in at least two stages. In a first stage, a mitral annular ring platform adapted for percutaneous delivery is delivered to and anchored in the mitral valve annulus. In the second stage, a valved-stent mitral valve prosthetic device adapted for percutaneously delivery is delivered to the mitral valve annulus for mounting in the mitral annular ring platform. This approach provides a consistent platform for accepting valved-stent mitral valve prosthetic devices from different vendors to be used.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Inventors: Joseph H. Gorman, III, Robert C. Gorman, Matthew J Gillespie
  • Patent number: 10092324
    Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state; wherein when at least a portion of the retrieval end of the inner sheath is transitioned to a compressed state following capture of the object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: October 9, 2018
    Assignees: The Trustees of the University of Pennsylvania, The Children's Hospital of Philadelphia
    Inventors: Matthew J. Gillespie, Joseph H. Gorman, III, Robert C. Gorman, Mark Piper
  • Publication number: 20180271685
    Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from a subject's internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include the use of a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state so that the object can be enclosed within the interior space after passing through the mouth of the retrieval end.
    Type: Application
    Filed: September 2, 2016
    Publication date: September 27, 2018
    Inventors: Matthew J. GILLESPIE, Mark PIPER, Joseph H. GORMAN, III, Robert C. GORMAN
  • Publication number: 20180200059
    Abstract: Disclosed are annuloplasty rings having defined relationships between the intercommisural width and ratio of septo-lateral width to intercommisural width. The saddle-shaped annuloplasty rings may have a ratio of SLW to ICW of x±(0.07×x) when the ring has an intercommisural width of y, as determined according to the formula x=(y?124)/?100.
    Type: Application
    Filed: July 11, 2016
    Publication date: July 19, 2018
    Inventors: Joseph H. GORMAN, III, Robert C. GORMAN
  • Patent number: 9919054
    Abstract: The invention relates to compositions comprising (i) biocompatible hydrogel and (ii) one or more therapeutic agents contained within said hydrogel; wherein the hydrogel is cross-linked utilizing a cross-linker comprising a peptide sequence that is capable of being degraded by an enzyme; the therapeutic agent being effective as a treatment of a condition related to the presence of the enzyme.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: March 20, 2018
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Jason Alan Burdick, Robert C. Gorman, Joseph H. Gorman, III, Brendan Patrick Purcell
  • Publication number: 20170365057
    Abstract: A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (FEA) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3D transesophageal echocardiography (rt-3DTEE). Volumetric images of the mitral valve at mid-systole may be analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation to obtain, a compact representation of shape.
    Type: Application
    Filed: September 6, 2017
    Publication date: December 21, 2017
    Inventors: Benjamin M. Jackson, Robert C. Gorman, Joseph H. Gorman, Alison M. Pouch, Chandra M. Sehgal, Paul A. Yushkevich, Brian B. Avants, Hongzhi Wang