Patents by Inventor Joseph M. Fernandez

Joseph M. Fernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240065641
    Abstract: A monitor mount is configured to detachably secure a first monitor and/or a second monitor individually or concurrently. The first monitor is further configured to be detachably secured to the second monitor independently from either monitor being secured to the monitor mount. The second monitor includes a mounting area in which the first monitor is mounted, and the first monitor and the second monitor are configured such that the first monitor is interchangeably insertable into the mounting area from a first lateral direction and a second lateral direction that is opposite to the first lateral direction. Accordingly, the second monitor includes a dual-entry feature that enables the first monitor to be inserted from either lateral side of the second monitor.
    Type: Application
    Filed: August 27, 2021
    Publication date: February 29, 2024
    Applicant: Drägerwerk AG & Co. KGaA
    Inventors: Clifford M. Risher-Kelly, John C. Magill, Zachary Kurt Hennings, Thomas Swyst, Christopher Aiston, Andrew T. Provencher, Peter A. Lund, Joseph Fallon, Ricardo Luis FERNANDEZ
  • Publication number: 20220162675
    Abstract: Provided herein are methods for mapping modified nucleotide residues in nucleic acids. The methods include providing a nucleic acid sample in which non-target or target modified and unmodified nucleotide residues are converted to form of a different nucleotide (such a “C” being converted to “T”). Second strand synthesis is then performed on the converted nucleic acids using a set of anchored-base primers. Each primer in the set of anchored-base primers comprises one or more anchor bases at the 3? terminus that are complementary to the target nucleotide (e.g., “G” or “CpG”), and a sequence of nucleotides selected from a set of sequences that could be a fully or partially degenerate set of sequences. For example, the sequence could be 5?-XnG-3? and/or 5?-X(n?1)CG-3?, wherein X is any base, and n=2 to 25. Double-stranded nucleic acid products can be analyzed, for example by amplification and high throughput sequencing.
    Type: Application
    Filed: December 23, 2020
    Publication date: May 26, 2022
    Applicants: Active Motif, Inc., Active Motif, Inc.
    Inventors: Benjamin F. DELATTE, Eddie W. ADAMS, Joseph M FERNANDEZ
  • Publication number: 20220162676
    Abstract: Provided herein is a new molecular marker in DNA: N-4-acetyldeoxycytidine (“N4-acdC”). Also provided herein are methods of detecting N4-acdC residues in DNA molecules as well as methods of using detected N4-acdC residues, for example in genetic mapping and diagnostics.
    Type: Application
    Filed: December 22, 2020
    Publication date: May 26, 2022
    Inventors: Benjamin F. DELATTE, Mikhail Tchoub, Eddie W. ADAMS, Joseph M FERNANDEZ
  • Patent number: 10837142
    Abstract: Coating compositions, including high degree of substitution (DS), viscosity optimized starches, are disclosed for use in non-barrier paper coatings. Paper coated with the same is disclosed as well as methods of making the coating compositions and coated papers.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: November 17, 2020
    Assignee: SAPPI NORTH AMERICA, INC.
    Inventors: Joseph M. Fernandez, Arbin Rajbanshi, Qi Wang
  • Publication number: 20200190222
    Abstract: Degraded hydroxyalkylated starches and methods of preparing the same from waxy, normal, or modified starches are provided. The starches can be prepared by several approaches that involve acid or enzyme degrading either before or after starch modification with an alkylene oxide. The modified and degraded starches exhibit improved swelling characteristics, solution stability of cooked starch, improved film-forming properties and/or improved coating performance. In addition, the degraded hydroxyalkylated starches can be used as a fat replacement in foods, in film-forming compositions, in coating compositions, and to encapsulate other materials.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 18, 2020
    Inventors: Yong-Cheng Shi, Joseph M. Fernandez, Arbin Rajbanshi, Qi Wang, Zhenhua Sun
  • Publication number: 20200190740
    Abstract: Coating compositions, including high degree of substitution (DS), viscosity optimized starches, are disclosed for use in non-barrier paper coatings. Paper coated with the same is disclosed as well as methods of making the coating compositions and coated papers.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 18, 2020
    Inventors: Joseph M. FERNANDEZ, Arbin RAJBANSHI, Qi WANG
  • Patent number: 8637264
    Abstract: Methods of using microarrays to simplify analysis and characterization of genes and their function are provided. Such methods can be used to identify and characterize antibodies having binding affinity for a specific target antigen. A method of determining gene expression at the protein level by contacting an array of characterized or uncharacterized antibodies on a solid surface with one or more proteins and identifying the antibodies to which said protein(s) binds also is provided. This method can be used to compare the protein expression in two different populations of cells, such as normal cells and cancer cells or resting cells and stimulated cells. In addition, a method of determining gene expression at the protein level by contacting a microarray of nucleic acid samples derived from a variety of different sources with one or more nucleic acid probes then identifying the sample or samples to which the probe binds is provided.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: January 28, 2014
    Assignee: Life Technologies Corporation
    Inventors: James P. Hoeffler, Joseph M. Fernandez, Marc S. Nasoff
  • Publication number: 20120004131
    Abstract: Methods of using microarrays to simplify analysis and characterization of genes and their function are provided. Such methods can be used to identify and characterize antibodies having binding affinity for a specific target antigen. A method of determining gene expression at the protein level by contacting an array of characterized or uncharacterized antibodies on a solid surface with one or more proteins and identifying the antibodies to which said protein(s) binds also is provided. This method can be used to compare the protein expression in two different populations of cells, such as normal cells and cancer cells or resting cells and stimulated cells. In addition, a method of determining gene expression at the protein level by contacting a microarray of nucleic acid samples derived from a variety of different sources with one or more nucleic acid probes then identifying the sample or samples to which the probe binds is provided.
    Type: Application
    Filed: June 30, 2011
    Publication date: January 5, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: James P. Hoeffler, Joseph M. Fernandez, Marc S. Nasoff
  • Patent number: 7794946
    Abstract: The invention disclosed herein comprises methods of using microarrays to simplify analysis and characterization of genes and their function. In one aspect of the invention the methods are used to identify and characterize antibodies having binding affinity for a specific target antigen. The invention further comprises a method of determining gene expression at the protein level comprising contacting an array of characterized or uncharacterized antibodies on a solid surface with one or more proteins and identifying the antibodies to which said protein(s) binds. This method can be additionally used to compare the protein expression in two different populations of cells, such as normal cells and cancer cells or resting cells and stimulated cells.
    Type: Grant
    Filed: February 4, 1999
    Date of Patent: September 14, 2010
    Assignee: Life Technologies Corporation
    Inventors: James P. Hoeffler, Joseph M. Fernandez, Marc S. Nasoff
  • Publication number: 20100022407
    Abstract: Methods of using microarrays to simplify analysis and characterization of genes and their function are provided. Such methods can be used to identify and characterize antibodies having binding affinity for a specific target antigen. A method of determining gene expression at the protein level by contacting an array of characterized or uncharacterized antibodies on a solid surface with one or more proteins and identifying the antibodies to which said protein(s) binds also is provided. This method can be used to compare the protein expression in two different populations of cells, such as normal cells and cancer cells or resting cells and stimulated cells. In addition, a method of determining gene expression at the protein level by contacting a microarray of nucleic acid samples derived from a variety of different sources with one or more nucleic acid probes then identifying the sample or samples to which the probe binds is provided.
    Type: Application
    Filed: June 23, 2009
    Publication date: January 28, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: James P. Hoeffler, Joseph M. Fernandez, Marc S. Nasoff
  • Publication number: 20040229063
    Abstract: A coated printing sheet is provided that is suitable for conventional offset printing grades, exhibiting desirable surface and optical properties and providing a surface that is image receptive and resistant to coating failure. The coated printing sheet includes an image receptive coating containing a hard polymer pigment having a shear modulus of at least 5.0×109 dynes/cm2 and a film forming binder. The coated printing sheets resist burnishing and exhibit desirable properties, e.g., gloss, bulk, stiffness and smoothness, with minimal or no calendering.
    Type: Application
    Filed: June 23, 2004
    Publication date: November 18, 2004
    Applicant: S.D. WARREN SERVICES COMPANY, a Delaware corporation
    Inventors: Paul W. Concannon, Paul Durocher, Joseph M. Fernandez, Lisa A. Gubrud, Thomas A. Waecker
  • Patent number: 6777075
    Abstract: A coated printing sheet is provided that is suitable for conventional offset printing grades, exhibiting desirable surface and optical properties and providing a surface that is image receptive and resistant to coating failure. The coated printing sheet includes an image receptive coating containing a hard polymer pigment having a shear modulus of at least 5.0×109 dynes/cm2 and a film forming binder. The coated printing sheets resist burnishing and exhibit desirable properties, e.g., gloss, bulk, stiffness and smoothness, with minimal or no calendering.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: August 17, 2004
    Assignee: S.D. Warren Services Company
    Inventors: Paul W. Concannon, Paul Durocher, Joseph M. Fernandez, Lisa A. Gubrud, Thomas A. Waecker
  • Publication number: 20040009477
    Abstract: The present invention comprises a method for producing libraries of expressible gene sequences. The method of the invention allows for the simultaneous manipulation of multiple gene sequences and thus allows libraries to be created in an efficient and high throughput manner. The expression vectors containing verified gene sequences can be used to transfect cells for the production of recombinant proteins. The invention further comprises libraries of expressible gene sequences produced using the method of the invention and expression vectors used in the construction of said libraries.
    Type: Application
    Filed: November 21, 2001
    Publication date: January 15, 2004
    Applicant: INVITROGEN CORPORATION
    Inventors: Joseph M. Fernandez, John A. Heyman, James P. Hoeffler, Heather L. Marks-Hull, Michelle L. Sindici
  • Publication number: 20030175501
    Abstract: A coated printing sheet is provided that is suitable for conventional offset printing grades, exhibiting desirable surface and optical properties and providing a surface that is image receptive and resistant to coating failure. The coated printing sheet includes an image receptive coating containing a hard polymer pigment having a shear modulus of at least 5.0×109 dynes/cm2 and a film forming binder. The coated printing sheets resist burnishing and exhibit desirable properties, e.g., gloss, bulk, stiffness and smoothness, with minimal or no calendering.
    Type: Application
    Filed: March 15, 2002
    Publication date: September 18, 2003
    Inventors: Paul W. Concannon, Paul Durocher, Joseph M. Fernandez, Lisa A. Gubrud, Thomas A. Waecker
  • Publication number: 20020164656
    Abstract: Methods of using microarrays to simplify analysis and characterization of genes and their function are provided. Such methods can be used to identify and characterize antibodies having binding affinity for a specific target antigen. A method of determining gene expression at the protein level by contacting an array of characterized or uncharacterized antibodies on a solid surface with one or more proteins and identifying the antibodies to which said protein(s) binds also is provided. This method can be used to compare the protein expression in two different populations of cells, such as normal cells and cancer cells or resting cells and stimulated cells. In addition, a method of determining gene expression at the protein level by contacting a microarray of nucleic acid samples derived from a variety of different sources with one or more nucleic acid probes then identifying the sample or samples to which the probe binds is provided.
    Type: Application
    Filed: October 26, 2001
    Publication date: November 7, 2002
    Inventors: James P. Hoeffler, Joseph M. Fernandez, Marc S. Nasoff
  • Patent number: 5827657
    Abstract: Methods are described for producing recombinant DNA molecules from suitable host vectors and nucleic acids subjected to 3'-terminal transferase activity. In one embodiment, the method takes advantage of the single 3'-deoxy-adenosine monophosphate (dAMP) residues attached to the 3' termini of PCR generated nucleic acids. Vectors are prepared with recognition sequences that afford single 3'-terminal deoxy-thymidine monophosphate (dTMP) residues upon reaction with a suitable restriction enzyme. Thus, PCR generated copies of genes can be directly cloned into the vectors without need for preparing primers having suitable restriction sites therein. The invention also contemplates associated plasmid vectors and kits for implementing the methods.
    Type: Grant
    Filed: July 18, 1996
    Date of Patent: October 27, 1998
    Assignees: Invitrogen Corporation, Molecular Biology Resources, Inc.
    Inventors: Corinna Herrnstadt, Joseph M. Fernandez, Lloyd Smith, David A. Mead
  • Patent number: 5487993
    Abstract: Methods are described for producing recombinant DNA molecules from suitable host vectors and nucleic acids subjected to 3'-terminal transferase activity. In one embodiment, the method takes advantage of the single 3'-deoxy-adenosine monophosphate (dAMP) residues attached to the 3' termini of PCR generated nucleic acids. Vectors are prepared with recognition sequences that afford single 3'-terminal deoxy-thymidine monophosphate (dTMP) residues upon reaction with a suitable restriction enzyme. Thus, PCR generated copies of genes can be directly cloned into the vectors without need for preparing primers having suitable restriction sites therein. The invention also contemplates associated plasmid vectors and kits for implementing the methods.
    Type: Grant
    Filed: September 9, 1993
    Date of Patent: January 30, 1996
    Assignees: Invitrogen Corporation, Chimer
    Inventors: Corinna Herrnstadt, Joseph M. Fernandez, Lloyd Smith, David A. Mead
  • Patent number: 4395499
    Abstract: High strength pigment binders for paper coating having increased water retention and stability are disclosed. The coating compositions comprise an aqueous synthetic polymer latex and pigment and may contain other additives used in the art of pigmented paper coating. The latex comprises a dispersed interpolymer of a vinyl ester, a polyethylenically unsaturated comonomer and a ethylenically unsaturated mono- or dicarboxylic acid and optionally an alkyl acrylate.
    Type: Grant
    Filed: September 13, 1982
    Date of Patent: July 26, 1983
    Assignee: National Starch And Chemical Corporation
    Inventors: Josephine M. Rosenski, Joseph M. Fernandez