Patents by Inventor Joseph P. Sabatucci

Joseph P. Sabatucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6933322
    Abstract: This invention provides compounds of formula I, having the structure wherein R1, R4, A, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof, that are useful in treating metabolic disorders mediated by insulin resistance or hyperglycemia.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: August 23, 2005
    Assignee: Wyeth
    Inventors: Joseph P. Sabatucci, Craig E. Caufield, Alexander A. Greenfield, Schuyler Antane, Eamonn P. Morrison
  • Patent number: 6930131
    Abstract: This invention provides compounds of formula I, having the structure wherein R1, R2, R3, R4, A, and B are as defined in the specification, or a pharmaceutically acceptable salt thereof, that are useful in treating metabolic disorders mediated by insulin resistance or hyperglycemia.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: August 16, 2005
    Assignee: Wyeth
    Inventors: Joseph P. Sabatucci, Craig E. Caufield, Alexander A. Greenfield, Koi M. Morris, Eamonn P. Morrison
  • Patent number: 6900200
    Abstract: This invention provides novel substituted tricyclic carboxamides which act as oxytocin receptor competitive antagonists, as well as methods of their manufacture, pharmaceutical compositions and methods of their use in treatment, inhibition, suppression or prevention of preterm labor, dysmenorrhea and endometritis, suppression of labor at term prior to caesarean delivery, and to facilitate antinatal transport to a medical facility. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals; and may be useful in the prevention and treatment of disfunctions of the oxytocin system in the central nervous system including obsessive compulsive disorder (OCD) and neuropsychiatric disorders.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: May 31, 2005
    Assignee: Wyeth
    Inventors: Amedeo Arturo Failli, Jay Scott Shumsky, Thomas Joseph Caggiano, Joseph P. Sabatucci, Eugene John Trybulski, Kevin Anthony Memoli, William Jennings Sanders
  • Publication number: 20030216442
    Abstract: This invention provides compounds of formula I, having the structure 1
    Type: Application
    Filed: April 8, 2003
    Publication date: November 20, 2003
    Applicant: Wyeth
    Inventors: Joseph P. Sabatucci, Craig E. Caufield, Alexander A. Greenfield, Schuyler Antane, Eamonn P. Morrison
  • Publication number: 20030203941
    Abstract: This invention provides compounds of formula I, having the structure 1
    Type: Application
    Filed: April 8, 2003
    Publication date: October 30, 2003
    Applicant: Wyeth
    Inventors: Joseph P. Sabatucci, Craig E. Caufield, Alexander A. Greenfield, Koi M. Morris, Eamonn P. Morrison
  • Patent number: 5466830
    Abstract: This invention relates to 4-phenoxy (and 4-substituted phenoxy)5-hydroxy-2(5H)-furanones of the formula: ##STR1## where Z is ##STR2## where R is H, halogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl, trifluoromethyl, or ##STR3## and X is H, C.sub.1 -C.sub.8 alkyl, --O--C.sub.1 -C.sub.8 alkyl, or halogen;a process for their preparation, their use in the treatment of osteoporosis, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: May 18, 1994
    Date of Patent: November 14, 1995
    Assignee: American Home Products Corporation
    Inventor: Joseph P. Sabatucci
  • Patent number: 5336687
    Abstract: This invention relates to 4-phenoxy (and 4-substituted phenoxy)5-hydroxy-2(5H)-furanones of the formula: ##STR1## where Z is ##STR2## where R is H, halogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl, trifluoromethyl, or ##STR3## and X is H, C.sub.1 -C.sub.8 alkyl, --O--C.sub.1 -C.sub.8 alkyl, or halogen; a process for their preparation, their use in the treatment of osteoporosis, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: August 4, 1993
    Date of Patent: August 9, 1994
    Assignee: American Home Products Corporation
    Inventor: Joseph P. Sabatucci
  • Patent number: 5026725
    Abstract: This invention relates to 4-substituted-5-hydroxy-2(5H)-furanones, to the process for their preparation, to pharmaceutical compositions containing said 4-substituted-5-hydroxy-2(5H)-furanones and to the use of said 4-substituted-5-hydroxy-2(5H)-furanones for modifying the balance between bone production and bone resorption in a host animal, including man.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: June 25, 1991
    Assignee: American Home Products Corporation
    Inventors: Marshall A. Hayward, Joseph P. Sabatucci, Ivo L. Jirkovsky, Yvon Lefebvre
  • Patent number: 4916241
    Abstract: This invention relates to 4-substituted-5-hydroxy-2(5H)-furanones, to the process for their preparation, to pharmaceutical compositions containing said 4-substituted-5-hydroxy-2(5H)-furanones and to the use of said 4-substituted-5-hydroxy-2(5H)-furanones for modifying the balance between bone production and bone resorption in a host animal, including man.
    Type: Grant
    Filed: June 6, 1988
    Date of Patent: April 10, 1990
    Assignee: American Home Products Corporation
    Inventors: Marshall A. Hayward, Joseph P. Sabatucci, Ivo L. Jirkovsky, Yvon Lefebvre
  • Patent number: 4810699
    Abstract: Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1,5, 6, 7 and 8. The derivatives are useful anti-inflammatory and analgesic agents and methods for their preparation and use are also disclosed.
    Type: Grant
    Filed: September 21, 1987
    Date of Patent: March 7, 1989
    Assignee: American Home Products Corporation
    Inventors: Joseph P. Sabatucci, Christopher A. Demerson, Amadeo A. Failli
  • Patent number: 4748252
    Abstract: Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at position 8. The derivatives are useful anti-inflammatory and analgesic agents and methods and chemical intermediates for their preparation are also disclosed.
    Type: Grant
    Filed: January 28, 1987
    Date of Patent: May 31, 1988
    Assignee: American Home Products Corporation
    Inventors: Eckhardt S. Ferdinandi, Dominick Mobilio, Joseph P. Sabatucci, Leslie G. Humber
  • Patent number: 4686213
    Abstract: Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at position 8. The derivatives are useful anti-inflammatory and analgesic agents and methods and chemical intermediates for their preparation are also disclosed. Included are compounds of the formula ##STR1## wherein R.sup.1 is --H or lower alkyl containing 1 to 3 carbon atoms; R.sup.2 is --NH.sub.2, --NHCHO, --NHCONH.sub.2, --OCH.sub.3, oxo; R.sup.3 is --H or lower alkyl containing 1 to 3 carbon atoms and the pharmaceutically acceptable salts thereof when R.sup.1 is --H.
    Type: Grant
    Filed: August 15, 1986
    Date of Patent: August 11, 1987
    Assignee: American Home Products Corporation
    Inventors: Eckhardt S. Ferdinandi, Dominick Mobilio, Joseph P. Sabatucci, Leslie G. Humber