Patents by Inventor Joshua Clayton

Joshua Clayton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxazolidinone Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators
    Publication number: 20090012089
    Abstract: The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Application
    Filed: December 6, 2006
    Publication date: January 8, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Abdelmalik Slassi, Babu Joseph, Fupeng Ma, Ian Egle, Joshua Clayton, Methvin Isaac, Krzysztof Swierczek
  • Oxadiazole Derivatives and Their Use as Metabotropic Glutamate Receptor Potentiators 842
    Publication number: 20080306077
    Abstract: Compounds of Formula I: wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 11, 2008
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic Glutamate Receptor Oxadiazole Ligands and Their Use as Potentiators 841
    Publication number: 20080306088
    Abstract: Compounds of Formula I: wherein R1, R2, R3, R4 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 11, 2008
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic Glutamate-Receptor-Potentiating Isoindolones
    Publication number: 20080227794
    Abstract: Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined in the description, processes for the preparing the compounds, new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and uses of the compounds in therapy.
    Type: Application
    Filed: February 15, 2006
    Publication date: September 18, 2008
    Inventors: Bradford Van Wagenen, Radhakrishnan Ukkiramapandian, Joshua Clayton, Ian Egle, James R. Empfield, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi, Gary Steelman, Rebecca Urbanek, Sally Walsh
  • Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
    Publication number: 20080125431
    Abstract: Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
    Type: Application
    Filed: September 12, 2007
    Publication date: May 29, 2008
    Applicant: ASTRAZENECA
    Inventors: Ian Egle, Babu Joseph, Abdelmalik Slassi, Methvin Isaac, Fupeng Ma, Joshua Clayton
  • DAYLIGHT-READABLE DIGITAL PANEL METER WITH AUTO-BRIGHTNESS ADJUSTING LED DISPLAY
    Publication number: 20080106251
    Abstract: A digital panel meter includes a light-emitting diode (LED) display that is sufficiently bright to be easily read in direct sunlight. The digital panel meter also includes an ambient light-sensing circuit which automatically and continuously adjusts the brightness of the LED display in order to provide adequate readability in ambient light conditions ranging from full sunlight to total darkness.
    Type: Application
    Filed: November 1, 2007
    Publication date: May 8, 2008
    Inventors: Roy Manuel CABRAL, Joshua Clayton JOHNSTONE, Gary Charles PERRY
  • Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
    Publication number: 20070275966
    Abstract: The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Application
    Filed: December 6, 2006
    Publication date: November 29, 2007
    Applicants: NPS PHARMACEUTICALS, INC., AstraZeneca AB
    Inventors: Abdelmalik Slassi, Methvin Isaac, Ian Egle, Fupeng Ma, Babu Joseph, Joshua Clayton, Krzysztof Swierczek
  • Purine derivatives as kinase inhibitors
    Publication number: 20050090483
    Abstract: The present invention provides kinase inhibitors of Formula I.
    Type: Application
    Filed: March 4, 2003
    Publication date: April 28, 2005
    Inventors: Thomas Engler, Timothy Burkholder, Joshua Clayton, Clive Diefenbacher, Kelly Furness, James Henry, Yihong Li, Sushant Malhotra, Angela Marquart, Johnathan McLean, David Mendel, Jon Reel