Patents by Inventor Ju Woong Jang

Ju Woong Jang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9511172
    Abstract: Provided is a method of manufacturing an allogeneic soft-tissue transplant having autologous stem cells transplanted therein using an allogeneic soft-tissue support that is obtained from an allogeneic organism. In this regard, an allogeneic soft-tissue transplant that can replace a damaged soft-tissue of a human body is manufactured.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: December 6, 2016
    Assignee: Cellumed Co., Ltd.
    Inventors: Young Bock Shim, Kwang Il Lee, Ju Woong Jang, Jung Soo Lee
  • Publication number: 20150209476
    Abstract: Provided is a method of manufacturing an allogeneic soft-tissue transplant having autologous stem cells transplanted therein using an allogeneic soft-tissue support that is obtained from an allogeneic organism. In this regard, an allogeneic soft-tissue transplant that can replace a damaged soft-tissue of a human body is manufactured.
    Type: Application
    Filed: February 24, 2012
    Publication date: July 30, 2015
    Applicant: CELLUMED CO., LTD.
    Inventors: Young Bock Shim, Kwang ll Lee, Ju Woong Jang, Jung Soo Lee
  • Patent number: 8648178
    Abstract: The present invention relates to a method for purifying a protein belonging to the TGF-?, superfamily, preferably BMP, and more preferably BMP-2. According to the invention, the number of purification steps is reduced and the purification process is simplified, compared to the conventional BMP-2 purification method. Thus, the time required for purification can be shortened and the cost can be reduced. In addition, the invention solves the problem that as the time for purification increases and the number of purification steps increases, BMP-2 is degraded by protease or lost during purification steps, resulting in a decrease in the final yield of BMP-2. Thus, the invention increases the final yield of BMP-2.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: February 11, 2014
    Assignee: Korea Bone Bank Co., Ltd.
    Inventors: Young-Bock Shim, Yeong-Schick Kim, Yon-Rak Choi, Ju-Woong Jang
  • Patent number: 8431623
    Abstract: The present invention relates to a process for forming a porous poly(vinyl alcohol) (PVA) scaffold using a pore-forming agent, comprising: mixing PVA with the pore-forming agent to form micropores in the PVA scaffold and using an easily decomposable pore-forming agent after the formation of the pores to improve convenience and reduce the processing time in manufacturing the porous PVA scaffold as well as to enable a pore size and porosity to be selected. A process for forming a porous PVA scaffold using a pore-forming agent according to the present invention includes heating to melt the PVA, cooling the melted PVA and mixing the PVA with a heat-decomposable pore-forming agent, repeating the freezing/thawing of the mixed PVA to cure the PVA mixture, and stirring the cured PVA mixture with a hydrochloric acid solution at a high temperature of 65° C. or more to produce foam.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: April 30, 2013
    Assignee: Korea Bone Bank Co., Ltd.
    Inventors: Young-Bock Shim, Hong-Hee Jung, Yon-Rak Choi, Ju-Woong Jang
  • Patent number: 8409623
    Abstract: A cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute are provided, and more particularly, a cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute by which defatting, demineralizing, cleaning, and sterilizing processes are performed within a short time using a supersonic cabitation without damaging a surface and an inside of a bone tissue so as to further rapidly, effectively supply an allogeneic or xenogeneic bone graft substitute. Internal and external concentrations of Ca++ of the allogeneic or xenogeneic bone graft substitute are effectively removed so as to maintain physical properties of the allogenetic or xenogeneic bone graft substitute.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: April 2, 2013
    Assignee: Korea Bone Bank, Inc.
    Inventors: Young Bock Shim, Ju Woong Jang, Hyang Kim, Kwang Il Lee, Keun Soo Lee, Il Hwan Kim
  • Publication number: 20130060012
    Abstract: The present invention relates to a method for purifying a protein belonging to the TGF-?, superfamily, preferably BMP, and more preferably BMP-2. According to the invention, the number of purification steps is reduced and the purification process is simplified, compared to the conventional BMP-2 purification method. Thus, the time required for purification can be shortened and the cost can be reduced. In addition, the invention solves the problem that as the time for purification increases and the number of purification steps increases, BMP-2 is degraded by protease or lost during purification steps, resulting in a decrease in the final yield of BMP-2. Thus, the invention increases the final yield of BMP-2.
    Type: Application
    Filed: May 12, 2010
    Publication date: March 7, 2013
    Applicant: KOREA BONE BANK CO., LTD.
    Inventors: Young - Bock Shim, Yeong - Schick Kim, Yon - Rak Choi, Ju - Woong Jang
  • Patent number: 8080036
    Abstract: A pedicle screw is provided to be inserted into and fixed to a pedicle of a spinal disease patient, and more particularly, a pedicle screw in which a screw thread of a clamp screw is formed to have dents and protrusions with trapezoid cross-sections so as to form a predetermined gap with a screw thread of a fixing unit having dents and protrusions with rectangular cross-sections when the clamp screw is combined with the fixing unit, and the screw thread of the clamp screw has different pitches to disperse an external impact so as to further firmly combine the clamp screw with the fixing unit.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: December 20, 2011
    Assignee: Korea Bone Bank, Inc.
    Inventors: Young Bock Shim, Ju Woong Jang, Dae Kwan Kim, Sok Kyun Hong
  • Publication number: 20100267143
    Abstract: The present invention relates to a method for the surface modification of a polymeric scaffold for stem cell transplantation using a decellularized extracellular matrix. The method for the surface modification of the polymeric scaffold according to the present invention can embody a biomimetic surface environment that is effective for initial cell attachment, cell growth and differentiation of stem cells by modifying the surface of the polymeric scaffold using the decellularized extracellular matrix directly derived from specific tissue cells.
    Type: Application
    Filed: October 28, 2009
    Publication date: October 21, 2010
    Applicant: SNU R&DB Foundation
    Inventors: Kwi Deok Park, Hee Joong Kim, Dong Keun Han, Yu Jin Hong, Heung Jae Chun, Ju Woong Jang
  • Publication number: 20100166879
    Abstract: A cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute are provided, and more particularly, a cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute by which defatting, demineralizing, cleaning, and sterilizing processes are performed within a short time using a supersonic cabitation without damaging a surface and an inside of a bone tissue so as to further rapidly, effectively supply an allogeneic or xenogeneic bone graft substitute. Internal and external concentrations of Ca++ of the allogeneic or xenogeneic bone graft substitute are effectively removed so as to maintain physical properties of the allogenetic or xenogeneic bone graft substitute.
    Type: Application
    Filed: January 23, 2009
    Publication date: July 1, 2010
    Applicant: KOREA BONE BANK, INC.
    Inventors: Young Bock Shim, Ju Woong Jang, Hyang Kim, Kwang Il Lee, Keun Soo Lee, Il Hwan Kim
  • Publication number: 20100094353
    Abstract: A pedicle screw is provided to be inserted into and fixed to a pedicle of a spinal disease patient, and more particularly, a pedicle screw in which a screw thread of a clamp screw is formed to have dents and protrusions with trapezoid cross-sections so as to form a predetermined gap with a screw thread of a fixing unit having dents and protrusions with rectangular cross-sections when the clamp screw is combined with the fixing unit, and the screw thread of the clamp screw has different pitches to disperse an external impact so as to further firmly combine the clamp screw with the fixing unit.
    Type: Application
    Filed: January 23, 2009
    Publication date: April 15, 2010
    Applicant: KOREA BONE BANK, INC.
    Inventors: Young Bock Shim, Ju Woong Jang, Dae Kwan Kim, Sok Kyun Hong
  • Publication number: 20100028430
    Abstract: Disclosed are a bioactive protein-calcium phosphate ceramic composite for surface modification of a substrate for use as a substitute in the treatment of musculoskeletal disorders, and a preparation method thereof. The bioactive protein-calcium phosphate ceramic composite is prepared by mixing an aqueous solution of calcium phosphate and a protein, and impregnating the calcium phosphate and the protein in the resulting aqueous solution to co-precipitate them on a substrate, such as metals, ceramics and polymers, wherein the substrate is patterned, and different proteins are impregnated in at least two regions of the patterned regions.
    Type: Application
    Filed: July 22, 2006
    Publication date: February 4, 2010
    Applicant: Korea Bone Bank Co., Ltd.
    Inventors: Ju Woong Jang, Kwang II Lee, Hyang Kim, Young Bock Shim, Hyun Min Kim
  • Patent number: 6380113
    Abstract: The present invention relates to a zirconia/alumina composite and a manufacturing method thereof which provide a zirconia ceramic powder having a composition in a triangle composition range formed of three composition points of 92 mol % ZrO2-4 mol % Y2O3-4 mol % Nb2O5 (or Ta2O5), 89 mol % ZrO2-7 mol % Y2O3-4 mol % Nb2O5 (or Ta2O5), 86 mol % ZrO2-7 mol % Y2O3-7 mol % Nb2O5 (or Ta2O5) in a ternary system of ZrO2—Y2O3—Nb2O5 or Ta2O3 for thereby manufacturing a zirconia/alumina composite having a high strength and high toughness in a state that a low temperature degradation does not occur.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: April 30, 2002
    Assignee: Korea Institute of Science & Technology
    Inventors: Dae Joon Kim, Deuk Yong Lee, Ju Woong Jang
  • Patent number: 5556816
    Abstract: A method for the preparation of tetragonal zirconia polycrystal composite with high toughness and low-temperature degradation resistance. The method comprising adding transformable TZP of ZrO.sub.2 --Y.sub.2 O.sub.3 --Nb.sub.2 O.sub.5 /Ta.sub.2 O.sub.5 system to non-transformable TZP of ZrO.sub.2 --Y.sub.2 O.sub.3 --Nb.sub.2 O.sub.5 /Ta.sub.2 O.sub.5 system in an amount of not more than 60% by weight based on the total weight of the resulting mixture; and sintering the mixture at above 1,500.degree. C. Even though being exposed to a temperature ranging from 100.degree. to 400.degree. C. for a long time in air, the TZP composite prepared by the present method is rarely transformed into monoclinic zirconia and yet exhibits high toughness.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: September 17, 1996
    Inventors: Dae-Joon Kim, Ju-Woong Jang, Hyung-Jin Jung