Patents by Inventor Juan Dominguez

Juan Dominguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240071341
    Abstract: The claimed invention is a device and method of use for remotely actuated drumming with traditionally foot-operated drum sets. It is capable of operation with existing drum kits and sets, and adds ability to actuate a drum beater using the hand, arm, or other appendage such as an amputee residual limb to actuate the drum pedal remotely. The device comprises a traditional drum pedal mounted upon a drum pedal base, extendable tubes including extension tubes and down tubes, hinge posts and hinges, T-fittings, connector tabs, and a dais. A dais or platform for actuating the device is removeably attached to the extendable tube. The hinged attachment at the drum pedal base allows the drum pedal base to move up and down, thereby moving the foot pedal mechanism and actuating a beater that strikes the drum surface, creating sound.
    Type: Application
    Filed: August 24, 2022
    Publication date: February 29, 2024
    Inventor: Juan Dominguez
  • Patent number: 11723987
    Abstract: Provided herein are recombinant expression vector systems for expression by stem cells that allow for selective elimination of stem cell-derived tumorigenic cells, while preserving stem cell-derived therapeutic cells. The systems provided herein provide a means by which modified stem cells can be safely transplanted into subjects. In exemplary embodiments, the system comprises at least two suicide genes, one of which is specifically inactivated in cells exhibiting the desired phenotype and one of which is activated when the cell comprising the recombinant expression vector system behaves similarly to or the same as a tumor cell.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: August 15, 2023
    Assignee: UNIVERSITY OF MIAMI
    Inventor: Juan Dominguez-Bendala
  • Patent number: 11466255
    Abstract: Compositions and methods are provided for generating islet-like cell clusters. The methods include culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having Bone Morphogenetic Protein (BMP) activity (e.g., a BMP polypeptide). The effective amount of said molecule having BMP activity (e.g., BMP polypeptide) is sufficient to induce the formation of islet-like cell clusters. The methods further include treating or attenuating insulin-deficiency disorders, including type 1 diabetes. In one non-limiting embodiment, an insulin-deficiency disorder in a subject is treated or attenuated by culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having BMP activity (e.g., a BMP polypeptide) such that tho formation of islet-like cell clusters occurs.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: October 11, 2022
    Assignee: UNIVERSITY OF MIAMI
    Inventors: Juan Dominguez-Bendala, Luca Inverardi, Ricardo L. Pastori, Camillo Ricordi
  • Publication number: 20220118238
    Abstract: An injection for injecting at least one material into human keratinous materials that includes at least one treatment unit defining at least one cavity and at least one micro-implant made of said at least one material received in said cavity of the unit and having at least one portion having a same shape as the cavity; an injection device configured for applying a pressure to the at least one micro-implant to expel the latter out of the unit into the keratinous materials.
    Type: Application
    Filed: February 19, 2020
    Publication date: April 21, 2022
    Inventors: Dominique BORDEAUX, Ryan DONNELLY, Eneko LARRANETA LANDA, Juan DOMINGUEZ ROBLES
  • Publication number: 20210210478
    Abstract: Embodiments disclosed herein include electronic packages for optical to electrical switching. In an embodiment, an electronic package comprises a first package substrate and a second package substrate attached to the first package substrate. In an embodiment, a die is attached to the second package substrate. In an embodiment, a plurality of photonic engines are attached to a first surface and a second surface of the first package substrate. In an embodiment, the plurality of photonic engines are communicatively coupled to the die through the first package substrate and the second package substrate.
    Type: Application
    Filed: March 3, 2021
    Publication date: July 8, 2021
    Inventors: Susheel JADHAV, Juan DOMINGUEZ, Ankur AGRAWAL, Kenneth BROWN, Yi LI, Jing CHEN, Aditi MALLIK, Xiaoyu HONG, Thomas LILJEBERG, Andrew C. ALDUINO, Ling LIAO, David HUI, Ren-Kang CHIOU, Harinadh POTLURI, Hari MAHALINGAM, Lobna KAMYAB, Sasanka KANUPARTHI, Sushrutha Reddy GUJJULA, Saeed FATHOLOLOUMI, Priyanka DOBRIYAL, Boping XIE, Abiola AWUJOOLA, Vladimir TAMARKIN, Keith MEASE, Stephen KEELE, David SCHWEITZER, Brent ROTHERMEL, Ning TANG, Suresh POTHUKUCHI, Srikant NEKKANTY, Zhichao ZHANG, Kaiyuan ZENG, Baikuan WANG, Donald TRAN, Ravindranath MAHAJAN, Baris BICEN, Grant SMITH
  • Publication number: 20190247518
    Abstract: Provided herein are recombinant expression vector systems for expression by stem cells that allow for selective elimination of stem cell-derived tumorigenic cells, while preserving stem cell-derived therapeutic cells. The systems provided herein provide a means by which modified stem cells can be safely transplanted into subjects. In exemplary embodiments, the system comprises at least two suicide genes, one of which is specifically inactivated in cells exhibiting the desired phenotype and one of which is activated when the cell comprising the recombinant expression vector system behaves similarly to or the same as a tumor cell.
    Type: Application
    Filed: September 15, 2017
    Publication date: August 15, 2019
    Inventor: Juan Dominguez-Bendala
  • Patent number: 10310369
    Abstract: The invention relates to a stereoscopic reproduction system without glasses, comprising an image reproduction device using transparency acting as means for illuminating multiple viewers with polarized light, two image capture elements separated from one another, containing polarizing filters that allow each of them to capture two images, one with the reflection of the light in the corneas and the other one eliminating said reflection, processing means for obtaining the pixel-by-pixel subtraction of those two images, the location of each eye in each image being obtained as the geometric center of the reflections in each cornea and the parallax of each eye between the two capture elements.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: June 4, 2019
    Inventor: Juan Dominguez-Montes
  • Publication number: 20180155692
    Abstract: Compositions and methods are provided for generating islet-like cell clusters. The methods include culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having Bone Morphogenetic Protein (BMP) activity (e.g., a BMP polypeptide). The effective amount of said molecule having BMP activity (e.g., BMP polypeptide) is sufficient to induce the formation of islet-like cell clusters. The methods further include treating or attenuating insulin-deficiency disorders, including type 1 diabetes. In one non-limiting embodiment, an insulin-deficiency disorder in a subject is treated or attenuated by culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having BMP activity (e.g., a BMP polypeptide) such that tho formation of islet-like cell clusters occurs.
    Type: Application
    Filed: May 2, 2016
    Publication date: June 7, 2018
    Applicant: UNIVERSITY OF MIAMI
    Inventor: Juan Dominguez-Bendala
  • Patent number: 9964771
    Abstract: The present invention relates to a system for reproducing stereoscopic images comprising a projection screen, a projector, a first optical device, comprising a matrix of converging lenses having a focal distance f1, located in front of the projection screen, at a distance equal to twice the focal distance, a second optical device located in the focal plane of the first optical device and comprising a matrix of converging lenses, having a focal distance f2 equal to half the focal distance f1, located between the first optical device and the projection screen, and a third optical device located between the second optical device and the projection screen, in contact with the second optical device, the third optical device comprising a matrix of discriminating elements.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: May 8, 2018
    Inventor: Juan Dominguez-Montes
  • Publication number: 20180017858
    Abstract: The invention relates to a stereoscopic reproduction system without glasses, comprising an image reproduction device using transparency acting as means for illuminating multiple viewers with polarized light, two image capture elements separated from one another, containing polarizing filters that allow each of them to capture two images, one with the reflection of the light in the corneas and the other one eliminating said reflection, processing means for obtaining the pixel-by-pixel subtraction of those two images, the location of each eye in each image being obtained as the geometric center of the reflections in each cornea and the parallax of each eye between the two capture elements.
    Type: Application
    Filed: January 11, 2016
    Publication date: January 18, 2018
    Inventor: Juan Dominguez-Montes
  • Patent number: 9750770
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: September 5, 2017
    Assignees: The University of North Carolina at Chapel Hill, University of Miami-Diabetes Research Institute, Sapienza Università Di Roma
    Inventors: Lola M. Reid, Yunfang Wang, David A. Gerber, Giacomo Lanzoni, Luca Inverardi, Juan Dominguez-Bendala, Domenico Alvaro, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino
  • Publication number: 20170123220
    Abstract: The present invention relates to a system for reproducing stereoscopic images comprising a projection screen, a projector, a first optical device, comprising a matrix of converging lenses having a focal distance f1, located in front of the projection screen, at a distance equal to twice the focal distance, a second optical device located in the focal plane of the first optical device and comprising a matrix of converging lenses, having a focal distance f2 equal to half the focal distance f1, located between the first optical device and the projection screen, and a third optical device located between the second optical device and the projection screen, in contact with the second optical device, the third optical device comprising a matrix of discriminating elements.
    Type: Application
    Filed: June 15, 2015
    Publication date: May 4, 2017
    Inventor: Juan Dominguez-Montes
  • Patent number: 9533013
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 3, 2017
    Assignees: University of North Carolina at Chapel Hill, Sapienza Università Di Roma, University of Miami—Diabetes Research Institute
    Inventors: Lola M. Reid, Yunfang Wang, David A. Gerber, Giacomo Lanzoni, Luca Inverardi, Juan Dominguez-Bendala, Domenico Alvaro, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino
  • Publication number: 20160058798
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Applicants: University of North Carolina at Chapel Hill, Sapienza Università di Roma, University of Miami
    Inventors: Lola M. REID, Yunfang WANG, David A. GERBER, Giacomo LANZONI, Luca INVERARDI, Juan DOMINGUEZ-BENDALA, Domenico ALVARO, Vincenzo CARDINALE, Eugenio GAUDIO, Guido CARPINO
  • Patent number: 9175254
    Abstract: Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom. A gas-permeable membrane that includes perfluorocarbons or fluorocarbon derivatives (e.g., fluorinated silane, partially fluorinated silane) in its composition allows for the rapid, enhanced and uniform transfer of oxygen between the environment of cells or tissues contained in the cell culture container apparatus and the atmosphere of the incubator in which the cell culture apparatus is incubated.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: November 3, 2015
    Assignee: University of Miami
    Inventors: Christopher A. Fraker, Juan Dominguez-Bendala, Camillo Ricordi, Luca Inverardi
  • Publication number: 20140301985
    Abstract: A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 9, 2014
    Applicants: University of North Carolina at Chapel Hill, Sapienza Università di Roma, Diabetes Research Institute
    Inventors: Lola M. REID, Yunfang WANG, David A. GERBER, Giacomo LANZONI, Luca INVERARDI, Juan DOMINGUEZ-BENDALA, Domenico ALVARO, Vincenzo CARDINALE, Eugenio GAUDIO, Guido CARPINO
  • Publication number: 20140099717
    Abstract: Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom. A gas-permeable membrane that includes perfluorocarbons or fluorocarbon derivatives (e.g., fluorinated silane, partially fluorinated silane) in its composition allows for the rapid, enhanced and uniform transfer of oxygen between the environment of cells or tissues contained in the cell culture container apparatus and the atmosphere of the incubator in which the cell culture apparatus is incubated.
    Type: Application
    Filed: October 7, 2013
    Publication date: April 10, 2014
    Inventors: Christopher A. Fraker, Juan Dominguez-Bendala, Camillo Ricordi, Luca Inverardi
  • Patent number: 8551770
    Abstract: Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom. A gas-permeable membrane that includes perfluorocarbons in its composition allows for the rapid, enhanced and uniform transfer of oxygen between the environment of cells or tissues contained in the cell culture container apparatus and the atmosphere of the incubator in which the cell culture apparatus is incubated.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: October 8, 2013
    Assignee: University of Miami
    Inventors: Christopher A. Fraker, Juan Dominguez-Bendala, Ricordi Camillo, Luca Inverardi
  • Patent number: 8363976
    Abstract: The method renders unobservable cross images with low light intensity that appear in the combined reproduction of various different images. It consists of adding a percentage in negative of each of these cross images to the positive of the correct image prior to reproduction, so that as a result of this addition it is possible to obtain, instead of the cross image, a uniform, contrastless image, i.e. where all the points have the same light intensity, which is generally so small as to be unobservable.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: January 29, 2013
    Inventor: Juan Dominguez-Montes
  • Patent number: 7851360
    Abstract: Organometallic precursors and methods for deposition on a substrate in seed/barrier applications are herein disclosed. In some embodiments, the organometallic precursor is a ruthenium-containing, tantalum-containing precursor or combination thereof and may be deposited by atomic layer deposition, chemical vapor deposition and/or physical vapor deposition.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: December 14, 2010
    Assignee: Intel Corporation
    Inventors: Juan Dominguez, Adrien Lavoie, John Plombon, Joseph Han, Harsono Simka, David Thompson, John Peck