Abstract: A sample discharge syringe especially designed to be used with thin layer chromatography apparatus or TLC. The new syringe is designed to be used as one of a gang of syringes aligned on apparatus as disclosed and claimed in U.S. Pat. No. 3,738,493. The syringe has an anchoring button securely mounted at an area at the forward end of the syringe barrel or on the rear part of the needle which is mounted to the syringe barrel in communication with its interior passageway. The anchoring button has a flange plate in which the radial axis is normal to the elongated axis of the needle and the syringe body. This anchoring plate engages an anchoring rack on the top surface of the TLC apparatus which has a transverse slot to accommodate the flange plate and a slot normal to the transverse slot to accommodate the needle. A two-point hold down system is thus provided with the new syringe to assure immobilization of the gang of syringes as TLC samples are discharged when the needle tips are lowered to the TLC plate.