Patents by Inventor Judith Kelleher

Judith Kelleher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9592234
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: March 14, 2017
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Patent number: 9539261
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: January 10, 2017
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Publication number: 20160022682
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Application
    Filed: June 26, 2015
    Publication date: January 28, 2016
    Inventor: Judith KELLEHER-ANDERSSON
  • Publication number: 20150250798
    Abstract: The compounds and pharmaceutical compositions of the present invention are believed to significantly inhibit Dyrk1a activity which suggests that the agents could provide therapeutic benefit for Down syndrome, since Dyrk1a overproduction in Down syndrome appears to account for the developmental cognitive impairment and reduction in neurogenesis. The compounds and pharmaceutical compositions, administered during early post-natal development, may increase neurogenesis and thereby reduce cognitive impairment which may ultimately allow individuals with Down syndrome to live a more independent life.
    Type: Application
    Filed: February 4, 2015
    Publication date: September 10, 2015
    Inventor: Judith KELLEHER-ANDERSSON
  • Patent number: 9096613
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: August 4, 2015
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Publication number: 20150209371
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Application
    Filed: April 6, 2015
    Publication date: July 30, 2015
    Inventor: Judith KELLEHER-ANDERSSON
  • Patent number: 8999972
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: April 7, 2015
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Patent number: 8846914
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: September 30, 2014
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe
  • Publication number: 20140171428
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Application
    Filed: November 13, 2013
    Publication date: June 19, 2014
    Applicant: NEURONASCENT, INC.
    Inventor: Judith KELLEHER-ANDERSSON
  • Publication number: 20140147424
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: NEURALSTEM, INC.
    Inventors: Judith KELLEHER-ANDERSSON, Karl K. JOHE
  • Patent number: 8674098
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: March 18, 2014
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe
  • Patent number: 8609840
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: December 17, 2013
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Patent number: 8362262
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: January 29, 2013
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe
  • Publication number: 20120277218
    Abstract: The compounds and pharmaceutical compositions of the present invention are believed to significantly inhibit Dyrk 1a activity which suggests that the agents could provide therapeutic benefit for Down syndrome, since Dyrk 1a overproduction in Down syndrome appears to account for the developmental cognitive impairment and reduction in neurogenesis. The compounds and pharmaceutical compositions, administered during early post-natal development, may increase neurogenesis and thereby reduce cognitive impairment which may ultimately allow individuals with Down syndrome to live a more independent life.
    Type: Application
    Filed: September 22, 2010
    Publication date: November 1, 2012
    Applicant: Neuronascent, Inc.
    Inventor: Judith Kelleher-Andersson
  • Patent number: 8293488
    Abstract: A method for discovering neurogenic drugs is revealed. The method allows for systematic screening of test agents such as libraries of compounds. The method consists of exposing test agents to cultures of differentiating neural progenitor cells and measuring their effects on increasing the overall cell number and/or the number of neurons.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: October 23, 2012
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe
  • Publication number: 20120027733
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Applicant: NEURALSTEM, INC.
    Inventors: Judith KELLEHER-ANDERSSON, Karl K. Johe
  • Publication number: 20110319391
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Application
    Filed: September 13, 2011
    Publication date: December 29, 2011
    Inventor: Judith Kelleher-Anderson
  • Patent number: 8058434
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: November 15, 2011
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe
  • Patent number: 8039462
    Abstract: The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: October 18, 2011
    Assignee: Neuronascent, Inc.
    Inventor: Judith Kelleher-Anderson
  • Patent number: 8030492
    Abstract: Compositions containing neurogenic agents for inhibition of neuron death and inducing proliferation of neural cells are disclosed.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: October 4, 2011
    Assignee: Neuralstem, Inc.
    Inventors: Judith Kelleher-Andersson, Karl K. Johe