Patents by Inventor Julia Skokowa

Julia Skokowa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139342
    Abstract: The present invention relates to a nucleic acid molecule for an allele-specific editing of the ELANE gene, a vector comprising said nucleic acid molecule, a composition comprising said nucleic acid molecule or vector, a method in vitro for an allele-specific editing the ELENE gene in biological material including genetic material encoding said ELENE gene, and to a method for the prophylaxis and/or treatment and/or examination of a disease in a living being.
    Type: Application
    Filed: January 5, 2024
    Publication date: May 2, 2024
    Inventors: Julia SKOKOWA, Masoud NASRI, Perihan MIR
  • Publication number: 20240122882
    Abstract: The invention is directed to a compound for use in the prophylaxis and/or treatment of leukemia and/or the development of leukemia, a pharmaceutical composition for the prophylaxis and/or treatment of leukemia and/or the development of leukemia, comprising said compound, a method for the prophylaxis and/or treatment of leukemia and/or the development of leukemia in a living being, a single guide RNA (sgRNA) molecule which can be used in the method according to the invention.
    Type: Application
    Filed: October 18, 2023
    Publication date: April 18, 2024
    Applicant: EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET
    Inventors: Julia SKOKOWA, Benjamin DANNENMANN, Maksim KLIMIANKOU
  • Publication number: 20240018477
    Abstract: A composition is for the targeted knockout of a gene on double-stranded DNA in a biological cell. A method is for the targeted knockout of a gene on double-stranded DNA in a biological cell. A preparation includes a biological cell prepared in vitro. The biological cell includes a gene on double-stranded DNA, which is knocked-out in a targeted manner. A kit is for the targeted knockout of a gene on double-stranded DNA in a biological cell. Another method is for treating a subject afflicted with a disease associated with a mutated gene. Nucleic acid molecules can be a component of the composition and methods.
    Type: Application
    Filed: August 22, 2023
    Publication date: January 18, 2024
    Inventors: Julia Skokowa, Masoud Nasri, Perihan Mir
  • Publication number: 20100113343
    Abstract: The present inventions relates to the use of LEF-1 or functional fragments or homologs thereof, or enhancer or inducer of LEF-1 expression, activity or LEF-1 mediated signalling for the preparation of a pharmaceutical for preventing or treating all types of cytopenia of the myeloid or lymphoid lineage. In particular, the present invention relates to the treatment of severe congenital neutropenia. In another embodiment the present invention relates to the treatment of various types of cancer, in particular, of cancer involving altered granulocyte proliferation, survival and differentiation from granulocytes progenitor cells.
    Type: Application
    Filed: September 24, 2007
    Publication date: May 6, 2010
    Inventors: Julia Skokowa, Karl Welte