Patents by Inventor Jun-Hyoung Lee

Jun-Hyoung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240240815
    Abstract: An air purifier is disclosed.
    Type: Application
    Filed: January 8, 2024
    Publication date: July 18, 2024
    Applicant: COWAY Co., Ltd.
    Inventors: Jae Hoon KIM, Young Choon PARK, Seon Ho LEE, Jun Hyoung BAE, Dong Hee JANG
  • Publication number: 20240182859
    Abstract: Provided is a culture medium composition including turmeric, glycine, or insulin for culturing muscle stem cells for proliferation of muscle stem cells. According to the culture medium composition including turmeric, glycine, or insulin muscle stem cells for culturing muscle stem cells according to an aspect, the proliferation and differentiation abilities of cells do not degrade even when culturing muscle stem cells in vitro, resulting in effects of enabling mass culture of muscle stem cells. Accordingly, the culture medium composition is economical by effectively replacing a culture medium containing expensive bFGF, and since appropriate time of differentiation can be chosen when culturing muscle stem cells, the muscle stem cells can be differentiated when needed, thereby producing an effect of improving the quality of in vitro meat.
    Type: Application
    Filed: March 29, 2022
    Publication date: June 6, 2024
    Applicants: HYUPSUNG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANAGREEN CO., LTD.
    Inventors: Jiyou HAN, Jun Hyoung LEE, Hyeongun JEE, Jongbong PARK, Kyung Ah CHOI, Kyojin KANG
  • Patent number: 11365388
    Abstract: Provided is a method of producing a novel microorganism having a minimal genome. In particular, provided are a method of producing a novel microorganism having a smaller genome size than a wild-type, the method including the step of culturing the microorganism in a medium containing LB broth with stepwise decreasing concentrations of the LB broth; and a novel microorganism having a smaller genome size than a wild-type, produced by the above method. Despite the small genome size, the novel microorganism of the present disclosure may have a high growth rate, pyruvate production capacity, and protein translation efficiency thereby being usefully applied to industry such as production of recombinant proteins or pyruvate.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: June 21, 2022
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sun-Chang Kim, Byung-Kwan Cho, Donghui Choe, Bong Hyun Sung, Jun Hyoung Lee
  • Publication number: 20200239831
    Abstract: Provided is a method of producing a novel microorganism having a minimal genome. In particular, provided are a method of producing a novel microorganism having a smaller genome size than a wild-type, the method including the step of culturing the microorganism in a medium containing LB broth with stepwise decreasing concentrations of the LB broth; and a novel microorganism having a smaller genome size than a wild-type, produced by the above method. Despite the small genome size, the novel microorganism of the present disclosure may have a high growth rate, pyruvate production capacity, and protein translation efficiency thereby being usefully applied to industry such as production of recombinant proteins or pyruvate.
    Type: Application
    Filed: January 24, 2020
    Publication date: July 30, 2020
    Inventors: Sun-Chang Kim, Byung-Kwan Cho, Donghui Choe, Bong Hyun Sung, Jun Hyoung Lee
  • Publication number: 20190119688
    Abstract: Provided are a composition for solubilizing a target protein, including an expression cassette including a promoter and a gene encoding a fusion protein of a chaperone and an RNA-binding domain or an expression vector including the expression cassette; a transformant including the expression cassette or the expression vector; a kit including the composition or the transformant; and a method for producing the target protein by using the same.
    Type: Application
    Filed: January 31, 2018
    Publication date: April 25, 2019
    Inventors: Jun Hyoung LEE, Sun-Chang KIM, Almando Geraldi
  • Patent number: 9527886
    Abstract: Disclosed are an amphipathic peptide-lipase conjugate with enhanced lipase activity, a polynucleotide coding for the conjugate, an expression vector carrying the polynucleotide, a transformant anchoring the expression vector therein, a method for preparing the conjugate, a lipolysis method using the conjugate, and a method for producing biodiesel using the lipase.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: December 27, 2016
    Assignees: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, INTELLIGENT SYNTHETIC BIOLOGY CENTER
    Inventors: Sun-Chang Kim, Bong Hyun Sung, Kyung Seok Yang, Jun Hyoung Lee, Ki Jung Lim, Myung Keun Park
  • Publication number: 20140162331
    Abstract: Disclosed are an amphipathic peptide-lipase conjugate with enhanced lipase activity, a polynucleotide coding for the conjugate, an expression vector carrying the polynucleotide, a transformant anchoring the expression vector therein, a method for preparing the conjugate, a lipolysis method using the conjugate, and a method for producing biodiesel using the lipase.
    Type: Application
    Filed: August 10, 2012
    Publication date: June 12, 2014
    Inventors: Sun-Chang Kim, Bong Hyun Sung, Kyung Seok Yang, Jun Hyoung Lee, Ki Jung Lim, Myung Keun Park
  • Patent number: 8367380
    Abstract: The present invention relates generally to compositions and methods useful for, inter alia, production of commercial biologic products such as amino acids. More specifically, the present invention relates to genetically modified strains of microorganisms and the use thereof for the production of commercial products. The present invention also provides, inter alia, novel isolated DNA, nucleic acid, vectors and reduced genome bacteria.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: February 5, 2013
    Assignee: Scarab Genomics LLC
    Inventors: Frederick R. Blattner, Sun Chang Kim, Jun Hyoung Lee
  • Patent number: 8242242
    Abstract: The present invention relates to an artificial transcription factor which can artificially regulate gene expression of an E. coli, wherein the transcription factor comprising zinc finger proteins and transcription factors of prokaryote, and to be engineered E. coli using the same. Specifically, the artificial transcription factors comprising zinc finger domains and transcription factors in E. coli as effector domains are prepared and said artificial transcription library is introduced to E. coli to effectively and artificially regulate gene expression regardless of an activity of endogenous transcription factors in the E. coli and to induce E. coli having various desired phenotypes. Thus, only E. coli having the desired phenotypes useful for industries can be selected and used.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: August 14, 2012
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Sun-Chang Kim, Ju-Young Lee, Bong-Hyun Sung, Jun-Hyoung Lee, Sang-Hee Lee, Kui-Hyeon Kang
  • Publication number: 20100330623
    Abstract: The present invention relates generally to compositions and methods useful for, inter alia, production of commercial biologic products such as amino acids. More specifically, the present invention relates to genetically modified strains of microorganisms and the use thereof for the production of commercial products. The present invention also provides, inter alia, novel isolated DNA, nucleic acid, vectors and reduced genome bacteria.
    Type: Application
    Filed: February 19, 2009
    Publication date: December 30, 2010
    Applicant: SCARAB GENOMICS LLC
    Inventors: Frederick R. Blattner, Sun Chang Kim, Jun Hyoung Lee
  • Publication number: 20100136663
    Abstract: The present invention relates to an artificial transcription factor which can artificially regulate gene expression of an E. coli, wherein the transcription factor comprising zinc finger proteins and transcription factors of prokaryote, and to be engineered E. coli using the same. Specifically, the artificial transcription factors in E. coli as effector domains are prepared and said artificial transcription library is introduced to E. coli to effectively and artificially regulate gene expression regardless of an activity of endogenous transcription factors in the E. coli and to induce E. coli having various desired phenotypes. Thus, only E. coli having the desired phenotypes useful for industries can be selected and used.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 3, 2010
    Applicant: Korea Advanced Institute of Science and Technology
    Inventors: Sun-Chang KIM, Ju-Young Lee, Bong-Hyun Sung, Jun-Hyoung Lee, Sang-Hee Lee, Kui-Hyeon Kang
  • Publication number: 20090305421
    Abstract: Disclosed herein are a recombinant vector for deletion of specific chromosomal regions and a method for deletion of targeted microbial chromosomal regions using the same. Specifically, the recombinant vector comprises an arabinose-inducible promoter; a gene encoding a protein involved in lambda (?)-red recombination; a rhamnose-inducible promoter; and a gene encoding the I-SceI endonuclease. The present invention enables a convenient, rapid and markerless successive deletion of specific genes of microbes, as compared to a conventional method.
    Type: Application
    Filed: November 4, 2008
    Publication date: December 10, 2009
    Inventors: Sun Chang Kim, Kui Hyeon Kang, Byung Jo Yu, Jun Hyoung Lee, Bong Hyun Sung, Choong Hoon Lee, Sang Hee Lee, Ju Young Lee, Myung Keun Park
  • Publication number: 20070287180
    Abstract: The present invention relates to Escherichia coli variants that have increased antibiotics susceptibility, diffusion efficiency, and transformation efficiency. The variants can minimize the problems caused by biofilm formation such as increased resistance to antibiotics, decreased solute diffusion efficiency, and lowered transformation efficiency. According to the present invention, when selecting genetically-modified E. coli variants, not only a lesser amount of antibiotics is required when selecting desirable variants, but also the reduction of selection efficiency caused by biofilm formation by strains other than the variants to be selected, thus decreasing exhibiting resistance to antibiotics, can be avoided. Additionally, in the process of materials production, the amount of secreted products could be increased due to the increased solute diffusion efficiency. Furthermore, the increased transformation efficiency makes the mass production of useful materials easier.
    Type: Application
    Filed: September 1, 2005
    Publication date: December 13, 2007
    Inventors: Sun-Chang Kim, Choong-Hoon Lee, Bo-Ram Lim, Bong-Hyun Sung, Byung-Jo Yu, Won-Sik Lee, Jun-Hyoung Lee, Sang-Hee Lee