Abstract: (S)-(?)-4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperi-dine represented by the formula (IV): wherein * represents an asymmetric carbon.

Abstract: (S)-(−)-4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperi-dine represented by the formula (IV): 1

Abstract: The present invention is to provide a benzenesulfonic acid salt and a benzoic acid salt of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid represented by the formula (I): wherein * represents an asymmetric carbon, which are excellent in antihistaminic activity and anti-allergic activity, and a process for producing the same.

Abstract: The present invention is to provide a benzenesulfonic acid salt and a benzoic acid salt of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid represented by the formula (I): 1

Abstract: The present invention is to provide a benzenesulfonic acid salt and a benzoic acid salt of (S)-4-[4-[(4-chlorophenyl) (2-pyridyl)methoxy]piperidino]butanoic acid represented by the formula (I): wherein * represents an asymmetric carbon, which are excellent in antihistaminic activity and anti-allergic activity, and a process for producing the same.

Abstract: A cyclic amine derivative represented by the following formula: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted phenyl group, R.sup.2 represents a substituted of unsubstituted C.sub.1 -C.sub.8 aliphatic acyl group, a substituted or unsubstituted benzoyl group or a C.sub.1 -C.sub.4 alkoxycarbonyl group, and R.sup.3 represents a substituted 3 to 7 membered saturated cyclic amino group which may form a fused ring; or pharmaceutically acceptable salts thereof. The compounds and salts have excellent platelet aggregation inhibitory action. They are useful for the treatment and prevention of such diseases as embolism, thrombosis or arteriosclerosis and for the preparation of pharmaceutical compositions for such uses.

Abstract: Disclosed is a diarylmethoxypiperidine compound represented by the formula (I): ##STR1## wherein Ar.sup.1 and Ar.sup.2 each represent a phenyl group which may be substituted by a specific substituent, or a pyridyl group; X represents an alkylene group or a group having ##STR2## where n represents an integer of 1 to 8; Y represents oxygen atom or a group having --CONH--; and Z represents a phenyl group having at least one specific substituent as defined in the specification; and pharmaceutically acceptable salt thereof.

Abstract: A 5-fluorouracil derivative represented by the formula (1): ##STR1## wherein A represents a group represented by ##STR2## wherein R.sup.1 represents a hydrogen atom or OR.sup.5 group, R.sup.2, R.sup.3 and R.sup.5 may be the same or different and each represents a hydrogen atom or a group represented by the following formula (2): ##STR3## wherein R.sup.6 represents an acyl group, R.sup.7 represents a hydrogen atom, a straight or branched alkyl group, a cycloalkyl group, an aralkyl group, a lower alkenyl group or a phenyl group, and n is an integer of 0 to 6,provided that at least one of R.sup.2, R.sup.3 and R.sup.5 is a group represented by the formula (2), and the case whereinR.sup.2 and R.sup.5 are both hydrogen atoms is excluded,R.sup.4 represents a group represented by the formula (2), and X represents an alkylene group or a cycloalkylene group,and an antitumor agent containing the same as an active ingredient.

Abstract: Disclosed is a compound represented by Formula (I): ##STR1## wherein Ar.sup.1, Ar.sup.2, n, A, B and Z are as defined in claims. Disclosed are also a process for preparing the compound and pharmaceutical compositions containing the compound.The compound has an antihistamic and antiallergic effect.