Patents by Inventor Junji Miyahara

Junji Miyahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5270162
    Abstract: An autoradiographic gene-screening method employing a hybridization process, which comprises:(1) a step of transferring at least a portion of nucleic acids, fragments thereof or derivatives thereof resolved on a medium onto a transfer support to fix them thereonto;(2) a step of hybridizing the nucleic acids, fragments thereof or derivatives thereof fixed onto said transfer support with radioactively labeled probes; and(3) a step of obtaining locational information on the radioactively labeled substances on said transfer support, which comprises placing said transfer support having been subjected to the hybridization and a stimulable phosphor sheet in layers for a given period of time to cause said sheet to absorb at least a portion of radiation energy emitted by the radioactively labeled substances on said transfer support, exciting said stimulable phosphor sheet with an electromagnetic wave to release the radiation energy stored in said sheet as stimulated emission, and detecting the stimulated emission.
    Type: Grant
    Filed: July 29, 1991
    Date of Patent: December 14, 1993
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hisashi Shiraishi, Junji Miyahara, Hisatoyo Kato
  • Patent number: 5260190
    Abstract: An autoradiographic process for obtaining information on one or two dimensional location of radioactively labeled substances contained in a sample selected from the group consisting of tissue of an organism and a medium containing tissue of an organism and/or substances such as DNA originating from an organism,which comprises:placing said sample and a stimulable phosphor sheet having a phosphor layer comprising a stimulable phosphor dispersed in a binder together in layers for a certain period to cause said phosphor sheet to absorb at least a portion of radiation energy emitted by the radioactively labeled substances in said sample;scanning said phosphor sheet with an electromagnetic wave to release at least a portion of radiation energy stored in said phosphor sheet as stimulated emission; anddetecting the stimulated emission to obtain locational information on the radioactively labeled substances in the sample.
    Type: Grant
    Filed: July 6, 1989
    Date of Patent: November 9, 1993
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hisashi Shiraishi, Junji Miyahara, Hisatoyo Kato
  • Patent number: 5023014
    Abstract: A rare earth element activated complex halide phosphor and a radiation image storage panel having a fluorescent layer comprising the phosphor, which phosphor is represented by the formula:BaFX.multidot.aLiX'.multidot.bBeX.sub.2 ".multidot.cM.sup.III X.sub.3 '":dAwherein M.sup.III is at least one trivalent metal selected from the group consisting of Al and Ga, each of X, X', X" and X'" is at least one halogen selected from the group consisting of Cl, Br and I, A is at least one rare earth element selected from the group consisting of Eu, Tb, Ce, Tm, Dy, Pr, Ho, Nd, Yb, Er, Gd, Lu, Sm and Y, a, b and c are numbers satisfying the conditions of 0.ltoreq.a.ltoreq.0.ltoreq.b.ltoreq.0.1, 0.ltoreq.c.ltoreq.0.1 and 10.sup.-4 .ltoreq.a+b+c.ltoreq.0.1, and d is a number satisfying the condition of 10.sup.-6 .ltoreq.d.ltoreq.0.2.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: June 11, 1991
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hiroyuki Toda, Junji Miyahara, Kenji Takahashi
  • Patent number: 5006707
    Abstract: Each of two-dimensional sensors is exposed to an electron beam, which has passed through a sample, in a vacuum in order to store the energy from the electron beam on the two-dimensional sensor, and is then exposed to light or heat in order to release the stored energy as emitted light. The emitted light is photoelectrically detected and an image signal is thereby obtained which represents an electron microscope image of the sample. Read-out conditions which are to be used when the emitted light is detected are determined from an electron beam exposure amount which was set when the energy from the electron beam was stored on each two-dimensional sensor. Signals representing the read-out conditions determined for the two-dimensional sensors are stored in a storage device so that it is clear which read-out conditions correspond to which two-dimensional sensor.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: April 9, 1991
    Assignees: Fuji Photo Film Co., Ltd., Jeol Ltd.
    Inventors: Nobufumi Mori, Masahiro Ohnishi, Junji Miyahara, Tetsuo Oikawa, Yoshiyasu Harada
  • Patent number: 4952813
    Abstract: A radiographic intensifying screen comprising a support and a phosphor-containing resin layer provided thereon, in which the void ratio of said phosphor-containing resin layer is reduced in comparison with an ordinarily prepared phosphor-containing resin layer having the same binder-phosphor ratio and formed by a coating procedure conducted under an atmospheric pressure.The void ratio is not more than 85% of the void ratio of the ordinarily prepared phosphor-containing resin layer for a phosphor-containing resin layer which contains a resinous binder and a phosphor in a weight ratio of 1:1 to 1:25, the ratio of 1:25 being exclusive, and the void ratio is not more than 90% for a phosphor-containing resin layer which contains a resinuous binder and a phosphor in a weight ratio of 1:25 to 1:100.
    Type: Grant
    Filed: June 13, 1988
    Date of Patent: August 28, 1990
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Junji Miyahara, Akira Kitada
  • Patent number: 4950559
    Abstract: A radiation image storage panel comprising a support and a phosphor layer provided thereon which comprises a binder and a stimulable phosphor dispersed therein, characterized in that a light-reflecting layer containing a white pigment is provided between the support and the phosphor layer and that said light-reflecting layer is colored with a colorant capable of absorbing a portion of stimulating rays for the stimulable phosphor.
    Type: Grant
    Filed: April 4, 1989
    Date of Patent: August 21, 1990
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Satoshi Arakawa, Junji Miyahara, Kenji Takahashi
  • Patent number: 4922098
    Abstract: An electron microscope has a two-dimensional sensor located at the image-formation plane. The two-dimensional sensor stores electron beam energy and emits light upon exposure to light or heat. The filament is located at a position displaced from the principal optical axis of the electron beam so that the image of the filament may not be recorded on the two-dimensional sensor. The two-dimensional sensor is, for example, made of stimulable phosphor.
    Type: Grant
    Filed: October 11, 1988
    Date of Patent: May 1, 1990
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Nobufumi Mori, Yuichi Hosoi, Junji Miyahara
  • Patent number: 4910407
    Abstract: A radiation image storage panel comprising a support and a stimulable phosphor-containing resin layer provided thereon, in which the void ratio of said stimulable phosphor-containing resin layer is reduced in comparison with an ordinarily prepared stimulable phosphor-containing resin layer having the same binder-phosphor ratio and formed by a coating procedure conducted under an atmospheric pressure.The void ratio is not more than 85% of the void ratio of the ordinarily prepared stimulable phosphor-containing resin layer in which a resinous binder and a stimulable phosphor are contained in a weight ratio of 1:1 to 1:25, the ratio of 1:25 being exclusive, and the void ratio is not more than 90% for a stimulable phosphor-containing resin layer in which a resinous binder and a stimulable phosphor are contained in a weight ratio of 1:25 to 1:100.
    Type: Grant
    Filed: July 29, 1988
    Date of Patent: March 20, 1990
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Satoshi Arakawa, Junji Miyahara
  • Patent number: 4889990
    Abstract: In a system for recording and reproducing an electron microscope image, a two-dimensional sensor for storing electron beam energy is exposed to an electron beam passing through a sample in a vacuum to have the electron beam energy stored in the two-dimensional sensor. The two-dimensional sensor is then exposed to light or heated while the vacuum is maintained to release the stored energy as light emission. The light emitted by the two-dimensional sensor is photoelectrically detected to obtain an electric signal for reproducing a visible image.
    Type: Grant
    Filed: September 28, 1988
    Date of Patent: December 26, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Yuichi Hosoi, Junji Miyahara
  • Patent number: 4873440
    Abstract: In a system for outputting an electron microscope image, a two-dimensional sensor for storing electron beam energy thereon is exposed to an electron beam passing through a specimen in a vacuum to have the electron beam energy stored on the two-dimensional sensor, and is then exposed to light or heat to release the stored energy as light emission. The emitted light is photoelectrically detected to obtain image signals, and an electron beam image of the specimen is output on the basis of the image signals. The specimen is divided into a plurality of divisions, and the storage of the electron beam energy is carried out for each of the divisions. The image signals obtained at the divisions are combined to form composite image signals that represent an overall specimen image formed by a group of the divisions, and the image signals at the divisions are corrected so that signal values of the boundary areas of adjacent divisions become approximately equal to each other.
    Type: Grant
    Filed: December 24, 1987
    Date of Patent: October 10, 1989
    Assignees: Fuji Photo Film Co., Ltd., Jeol Ltd.
    Inventors: Nobufumi Mori, Takayuki Katoh, Tetsuo Oikawa, Yoshiyasu Harada, Junji Miyahara
  • Patent number: 4865967
    Abstract: An autoradiographic gene-screening method employing a hybridization process, which comprises:(1) a step of transferring a portion of genetic clones cultured on a culture medium onto a filter to fix them thereonto;(2) a step of hybridizing the genes of said clones fixed onto said filter with radioactively labeled probes;(3) a step of obtaining two dimensional information on the location of the radioactively labeled substances on the filter which comprises placing said filter having been subjected to the hybridization and a stimulable phosphor sheet in layers for a given period of time to cause said stimulable phosphor sheet to absorb at least a portion of radiation energy emitted by the radioactively labeled substances on the filter, exciting said sheet with an electromagnetic wave to release the radiation energy stored in said sheet as stimulated emission, and detecting the stimulated emission to obtain a locational information on the radioactively labeled substances on the filter; and(4) a step recovering th
    Type: Grant
    Filed: November 30, 1987
    Date of Patent: September 12, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hisashi Shiraishi, Junji Miyahara, Hisatoyo Kato
  • Patent number: 4818880
    Abstract: A radiation image read-out apparatus comprises an optical system for scanning a stimulable phosphor sheet carrying a radiation image stored therein by stimulating rays, a light guide member for guiding light emitted by the stimulable phosphor sheet upon exposure to stimulating rays, and a photoelectric converter for detecting the guided light. A film for preventing reflection of stimulating rays is closely contacted with a light input face of the light guide member. Or, a filter for absorbing the stimulating rays reflected by the stimulable phosphor sheet and transmitting the light emitted by the stimulable phosphor sheet is positioned between the stimulating ray incidence point on the stimulable phosphor sheet and the light input face of the light guide member.
    Type: Grant
    Filed: March 11, 1985
    Date of Patent: April 4, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Terumi Matsuda, Toshitaka Aagano, Junji Miyahara, Nobuyoshi Nakajima, Shigeru Saotome
  • Patent number: 4810886
    Abstract: A transmission-type electron microscope using a sensitive two-dimensional sensor in its micrograph-taking section acts as a recording medium for an electron beam. When the sensor is illuminated with an electron beam, it stores the energy of the beam. When the sensor is subsequently illuminated with light, it releases the stored energy as light. In accordance with the invention, at least a portion of the micrograph-taking section includes a member for reducing the amount of x-rays produced or a member for absorbing x-rays to shield the sensor from x-rays.
    Type: Grant
    Filed: January 5, 1988
    Date of Patent: March 7, 1989
    Assignees: Fuji Photo Film Co., Ltd., Jeol Ltd.
    Inventors: Nobufumi Mori, Takayuki Katoh, Junji Miyahara, Tetsuo Oikawa, Yoshiyasu Harada
  • Patent number: 4803359
    Abstract: A method for detecting radiation image which comprises steps of: causing a radiation image storage panel which comprises a phosphor layer containing a stimulable phosphor to absorb a radiation having passed through an object or radiated from an object; placing said radiation image storage panel and a photosensor composed of numerous photosensitive elements in regular and two-dimensional arrangement together in layers, and irradiating the panel with an electromagnetic wave to release the radiation energy stored in the panel as stimulated emission; and photoelectrically detecting the stimulated emission with said photosensor. A method for detecting radiation image using a radiation image detector which comprises a photosensitive member composed of numerous photosensitive elements and a phosphor layer containing a stimulable phosphor provided thereon is also disclosed.
    Type: Grant
    Filed: May 15, 1984
    Date of Patent: February 7, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Yuichi Hosoi, Junji Miyahara
  • Patent number: 4801801
    Abstract: A transmission-type electron microscope comprises a lens system including an electron gun for producing an electron beam that is focused and directed to a specimen. The lens system forms a magnified electron optical image of the specimen from the electron beam transmitted through the specimen. A two-dimensional sensor is mounted in the plane in which the magnified image is formed, the sensor acting to store the energy of the electron beam impinging on it and to release the stored energy as light when illuminated with light or heated. An electron beam-deflecting means is mounted in the lens system and acting to tilt the focal plane in which the magnified lens image is formed, in such a way that a straight line extending from the main optical axis of the electron beam between the electron gun and the specimen does not interset the two-dimensional sensor.
    Type: Grant
    Filed: June 8, 1987
    Date of Patent: January 31, 1989
    Assignees: Fuji Photo Film Co., Ltd., JEOL Ltd.
    Inventors: Nobufumi Mori, Junji Miyahara, Tetsuo Oikawa, Yoshiyasu Harada
  • Patent number: 4800136
    Abstract: A radiation image storage panel comprising a support and phosphor layers provided thereon which comprises a binder and a stimulable phosphor dispersed therein, characterized in that said phosphor layer include at least two layers of the first phosphor layer provided on the support and the second phosphor layer provided on the side nearer to the front surface of the panel than said first phosphor layer, and that the mixing ratio of the binder to the stimulable phosphor in the first phosphor layer is larger than the mixing ratio of the binder to the stimulable phosphor in the second phosphor layer.
    Type: Grant
    Filed: May 13, 1987
    Date of Patent: January 24, 1989
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Satoshi Arakawa, Junji Miyahara, Kenji Takahashi
  • Patent number: 4727420
    Abstract: An acoustooptic image can be formed by using a plate-like image sensor capable of increasing its optical density upon exposure to a radiation. The image sensor is exposed to a radiation bearing image information to record the image information on the image sensor. Then, pulsed light is applied to the image sensor to enable the same to generate a pressure wave commensurate with the recorded image information. The pressure wave is detected in synchronism with the pulsed light and converted into an electric signal, from which an image signal is reproduced. The image signal may be displayed on a CRT, or recorded on a magnetic recording medium, or reproduced on a photographic material.
    Type: Grant
    Filed: October 16, 1985
    Date of Patent: February 23, 1988
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Katsuhiro Kohda, Junji Miyahara
  • Patent number: 4700071
    Abstract: A two-dimensional image sensor such as a stimulable phosphor sheet is exposed under vacuum to an electron beam that has passed through a specimen to cause the two-dimensional image sensor to store the energy of the electron beam, then stimulating energy is applied to the two-dimensional image sensor for discharging light therefrom which represents the stored energy of the electron beam, and the light discharged from the two-dimensional image sensor is photoelectrically detected to produce an image signal. A reference image signal is also produced in a similar manner by exposing the two-dimensional image sensor to an electron beam that has not passed through the specimen. One of the first-mentioned image signal and the reference image signal is subtracted from the other per pixel to generate a difference signal, from which an electron microscope image of the specimen is reproduced.
    Type: Grant
    Filed: January 14, 1986
    Date of Patent: October 13, 1987
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Nobufumi Mori, Yuichi Hosoi, Kenji Takahashi, Junji Miyahara
  • Patent number: 4695725
    Abstract: A two-dimensional image sensor is exposed under vacuum to an electron beam having passed through a specimen in an electron microscope to enable the image sensor to store the energy of the electron beam. Then, stimulating energy is applied to the image sensor to discharge the stored energy as light. The light discharged from the image sensor is photoelectrically detected to produce an image signal. A defocus value of the image is detected on the basis of the image signal. The image signal is also subject electrically to the Fourier transform to produce a converted image signal indicative of a ring pattern. The degree of one ring, the length of minor and major axes of the ring, and the angle of inclination of the major axis are computed from the converted image signal for computing currents to be fed to a stigmeter of the electron microscope to eliminate astigmatism.
    Type: Grant
    Filed: December 9, 1985
    Date of Patent: September 22, 1987
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Nobufumi Mori, Yuichi Hosoi, Kenji Takahashi, Junji Miyahara
  • Patent number: 4694171
    Abstract: A two-dimensional image sensor is exposed under vacuum to an electron beam having passed through a specimen, and instantaneous light emitted from the image sensor upon exposure to the electron beam is detected with an image intensifier to reproduce an image observed to attain a desired focused condition and/or a desired field. After the image has been focused by the operator while observing the image, the image sensor is exposed under vacuum to an electron beam having been transmitted through the specimen to store the energy of the electron beam representative of the image of the specimen on the image sensor. Then, stimulating energy is applied to the image sensor for discharging light therefrom which represents the stored energy of the electron beam. The light discharged from the image sensor is photoelectrically detected to reproduce the transmitted electron-beam image of the specimen as a final output image thereof under the desired focused condition and/or with said desired field.
    Type: Grant
    Filed: November 26, 1985
    Date of Patent: September 15, 1987
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Yuichi Hosoi, Nobufumi Mori, Kenji Takahashi, Junji Miyahara