Abstract: A composition for film formation containing a polycyclic polyphenolic resin having repeating units derived from at least one monomer selected from the group consisting of aromatic hydroxy compounds represented by the formulas (1-0), (1A), and (1B), wherein the repeating units are linked by a direct bond between aromatic rings:

Abstract: It is intended to provide a novel method for treating a cancer using an FGFR inhibitor that exhibits a remarkably excellent antitumor effect and has fewer side effects. The present invention provides a combination preparation for the treatment of a malignant tumor comprising a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof, and one or more additional compound(s) having an antitumor effect or pharmaceutically acceptable salt(s) thereof, and a pharmaceutical composition comprising both the active ingredients. The present invention also provides an antitumor effect enhancer, an antitumor agent, a kit for malignant tumor treatment, etc. comprising a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a tumor treatment method using a pyrimidine compound or a salt thereof. An antitumor agent that contains a pyrimidine compound represented by general formula (I) or a salt thereof, said antitumor agent being to be administered in combination with another antitumor agent. (In the formula, R1 represents a C1-C4 alkyl group optionally having a C1-C4 alkoxy group as a substituent, or a C3-C4 cycloalkyl group; R2 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group optionally having, as a substituent(s), one to five C1-C4 alkoxy groups or one to five fluorine atoms, or a C1-C6 alkoxy group; R3 represents a hydrogen atom, or a C1-C4 alkyl group optionally having, as a substituent(s), one to five fluorine atoms; R4 represents a hydrogen atom or a C1-C4 alkyl group; and R5 represents a phenyl group optionally having one to three substituents selected from fluorine atoms and chlorine atoms.

Abstract: The present disclosure provides a lubricating composition that includes one or more boron-containing compounds and method of forming the same. The lubricating composition includes one or more boron-containing compounds, one or more metal-based detergents, one or more amine-based antioxidants, one or more phenol-based antioxidants, and a base oil balance. The lubricating composition includes greater than or equal to about 60 ppm to less than or equal to about 300 ppm of boron atoms that define the one or more boron-containing compounds; greater than or equal to about 1,100 ppm of metal atoms that define the one or more metal-based detergents; greater than or equal to about 0.70 wt. % to less than or equal to about 2.00 wt. % of the one or more amine-based antioxidants; and greater than or equal to about 0.30 wt. % to less than or equal to about 2.00 wt. %, of the one or more phenol-based antioxidants.

Abstract: An operation information analyzer includes: an information collection unit 11 configured to collect event information on events that have occurred during operation of an apparatus 20 including a plurality of devices 21; an information analysis unit 12 configured to organize the collected event information to generate and store index values used to evaluate operation conditions of the apparatus 20; and an information presentation unit 13 configured to present the index values stored in the information analysis unit 12 to a user. The information analysis unit 12 generates the index values for each period sectioned based on a change in an operation state of the apparatus.

Abstract: It is intended to provide a novel method for treating a cancer using an FGFR inhibitor that exhibits a remarkably excellent antitumor effect and has fewer side effects. The present invention provides a combination preparation for the treatment of a malignant tumor comprising a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof, and one or more additional compound(s) having an antitumor effect or pharmaceutically acceptable salt(s) thereof, and a pharmaceutical composition comprising both the active ingredients. The present invention also provides an antitumor effect enhancer, an antitumor agent, a kit for malignant tumor treatment, etc. comprising a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: An operation information analyzer includes: an information collection unit 11 configured to collect event information on events that have occurred during operation of an apparatus 20 including a plurality of devices 21; an information analysis unit 12 configured to organize the collected event information to generate and store index values used to evaluate operation conditions of the apparatus 20; and an information presentation unit 13 configured to present the index values stored in the information analysis unit 12 to a user. The information analysis unit 12 generates the index values for each period sectioned based on a change in an operation state of the apparatus.

Abstract: The lubricating oil composition according to the present invention is one including a base oil, (A) a substituted hydroxy aromatic carboxylic acid ester derivative represented by at least one of the general formula (I) and the general formula (II), and (B) a heterocyclic compound represented by the general formula (III) or (IV) blended therein, wherein a phosphorus content is 0.06 mass % or less on the basis of a total amount of the composition, and a sulfated ash content is 1.2 mass % or less on the basis of a total amount of the composition. The lubricating oil composition is capable of maintaining high-temperature detergency and acid neutralizing properties, even when amounts of a phosphorus component-containing additive and a metallic detergent are reduced.

Abstract: Lubricating oil compositions may include a base oil, a succinimide compound, and a thioheterocyclic compound. Such compositions may have a sulfur content of 0.10 mass % to 1.00 mass % based on a total amount of the composition. A phosphorus content represented by P in mass % and a sulfated ash content represented by M in mass %, based on the total amount of such compositions, may satisfy any of conditions A to C: condition A: P<0.03, and M<0.3; condition B: P<0.03 and 0.3?M?0.6; and condition C: 0.03?P?0.06 and M<0.3.

Abstract: The present disclosure relates to a lubricating oil composition containing a base oil, a thioheterocyclic compound represented by the formula: (R1)k—(S)m—As—(S)n—(R2)l, and an aminoalcohol compound containing, in the molecule thereof, a piperazine moiety and one or more hydroxyl groups. The lubricating oil composition has a phosphorus content (P mass %) and a sulfated ash content (M mass %), based on a total mass of the lubricating oil composition, satisfying any of the following conditions A to C: condition A: P<0.03, and M<0.3; condition B: P<0.03, and 0.3?M?0.6; and condition C: 0.03?P?0.06, and M<0.3.

Abstract: A lubricating oil additive composition contains a borated succinimide derivative and an amino alcohol compound. A lubricating oil composition containing the lubricating oil additive composition is excellent in high-temperature detergency and base value retention (long-drain capabilities) even though a blended content of a metal detergent is low and an ash content is small.

Abstract: The lubricating oil composition according to the present invention is one including a base oil, (A) a substituted hydroxy aromatic carboxylic acid ester derivative represented by at least one of the general formula (I) and the general formula (II), and (B) a heterocyclic compound represented by the general formula (III) or (IV) blended therein, wherein a phosphorus content is 0.06 mass % or less on the basis of a total amount of the composition, and a sulfated ash content is 1.2 mass % or less on the basis of a total amount of the composition. The lubricating oil composition is capable of maintaining high-temperature detergency and acid neutralizing properties, even when amounts of a phosphorus component-containing additive and a metallic detergent are reduced.

Abstract: Provided is a detergent-dispersant for a lubricant having excellent detergency and dispersibility effects. Specifically provided are: a detergent-dispersant including a heterocyclic compound having a heterocyclic skeleton derived from a compound selected from the group consisting of pyridines, pyrroles, pyrimidines, pyrazoles, pyridazines, imidazoles, pyrazines, triazines, triazoles, tetrazoles, oxazoles, oxadiazoles, thiazoles, thiadiazoles, furans, dioxanes, pyrans, and thiophenes; and an additive composition for a lubricant and a lubricant composition, each containing the detergent-dispersant.

Abstract: A lubricating oil additive composition contains a borated succinimide derivative and an amino alcohol compound. A lubricating oil composition containing the lubricating oil additive composition is excellent in high-temperature detergency and base value retention (long-drain capabilities) even though a blended content of a metal detergent is low and an ash content is small.

Abstract: The invention provides a lubricating oil composition for an engine made of aluminum alloy containing a base oil, a succinimide compound, and a thioheterocyclic compound represented by the following formula (I) and has a sulfur content of 0.10 mass % to 1.00 mass % based on the total amount of the composition, and a phosphorus content and a sulfated ash content, based on the total amount of the composition, falling within specific ranges, and a lubrication method employing the composition. The composition exhibits excellent wear resistance to aluminum alloy sliding parts of engines and can considerably reduce the high-phosphorus ZnDTP content and the metallic detergent content, while excellent wear resistance to aluminum alloy is maintained.

Abstract: The lubricating oil composition for internal combustion engines of the present invention contains a base oil, a thioheterocyclic compound represented by the following formula (I) (R1)k—(S)mAS-(S)n—(R2)l ??(I) (wherein As represents a thioheterocycle; each of R1 and R2 represents a hydrogen atom, an amino group, a C1 to C50 hydrocarbyl group selected from among an alkyl group, a cycloalkyl group, an alkenyl group, a cycloalkenyl group, and an aryl group, or, in the case of a hydrocarbyl group, a C1 to C50 heteroatom-containing group having an atom selected from among an oxygen atom, a nitrogen atom, and a sulfur atom, in the hydrocarbyl group; and each of k, l, m, and n is an integer of 0 to 5), and an aminoalcohol compound having, in the molecule thereof, one or more amino groups and one or more hydroxyl groups, wherein the composition has a phosphorus content (P mass %) and a sulfated ash content (M mass %), based on the total amount of the composition, satisfying any of the following conditions A to C: c

Abstract: Provided is a detergent-dispersant for a lubricant having excellent detergency and dispersibility effects. Specifically provided are: a detergent-dispersant including a heterocyclic compound having a heterocyclic skeleton derived from a compound selected from the group consisting of pyridines, pyrroles, pyrimidines, pyrazoles, pyridazines, imidazoles, pyrazines, triazines, triazoles, tetrazoles, oxazoles, oxadiazoles, thiazoles, thiadiazoles, furans, dioxanes, pyrans, and thiophenes; and an additive composition for a lubricant and a lubricant composition, each containing the detergent-dispersant.

Abstract: Provided is a detergent-dispersant for a lubricant having excellent detergency and dispersibility effects. Specifically provided are: a detergent-dispersant including a heterocyclic compound having a heterocyclic skeleton derived from a compound selected from the group consisting of pyridines, pyrroles, pyrimidines, pyrazoles, pyridazines, imidazoles, pyrazines, triazines, triazoles, tetrazoles, oxazoles, oxadiazoles, thiazoles, thiadiazoles, furans, dioxanes, pyrans, and thiophenes; and an additive composition for a lubricant and a lubricant composition, each containing the detergent-dispersant.

Abstract: Provided is a detergent-dispersant for a lubricant having excellent detergency and dispersibility effects. Specifically provided are: a detergent-dispersant including a heterocyclic compound having a heterocyclic skeleton derived from a compound selected from the group consisting of pyridines, pyrroles, pyrimidines, pyrazoles, pyridazines, imidazoles, pyrazines, triazines, triazoles, tetrazoles, oxazoles, oxadiazoles, thiazoles, thiadiazoles, furans, dioxanes, pyrans, and thiophenes; and an additive composition for a lubricant and a lubricant composition, each containing the detergent-dispersant.

Abstract: A detergent dispersant contains a nitrogen-containing compound represented by the following formula (1). A lubricating oil composition contains the detergent dispersant. Each symbol in the formula means the same as described in the description.