Patents by Inventor Junya KIKUISHI

Junya KIKUISHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10525078
    Abstract: A solid dialysis A agent is provided, which is to be used in preparing a bicarbonate dialysis fluid, wherein: the solid dialysis A agent contains glucose, acetic acid and an acetate salt; at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate; and the acetic acid/acetate salt molar ratio is adjusted to 1/0.5 to 1/2. This solid dialysis A agent makes it possible to prepare a bicarbonate dialysis fluid which has a total acetate ion concentration of 2 to less than 6 mEq/L. Further, the dialysis A agent exhibits excellent stability of ingredients and a reduced acetic acid odor.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: January 7, 2020
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Michiko Myose, Hiroshi Noguchi, Junya Kikuishi, Hideyuki Aoyama, Mina Hashimoto, Yusuke Yoshimoto
  • Patent number: 10251988
    Abstract: A dialysis agent A including a mixture containing glucose, acetic acid, and acetate salt, but not sodium bicarbonate, wherein the molar ratio of acetic acid:acetate salt is 1:0.5 to 1:2, and wherein a total amount of the acetic acid and acetate salt contained in the dialysis agent A is between 2 mEq/L and 6 mEq/L when the dialysis agent A is dissolved in 1 L of a bicarbonate dialysate.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: April 9, 2019
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Noguchi, Michiko Myose, Junya Kikuishi, Mina Hashimoto, Hideyuki Aoyama
  • Publication number: 20180169317
    Abstract: A dialysis agent A including a mixture containing glucose, acetic acid, and acetate salt, but not sodium bicarbonate, wherein the molar ratio of acetic acid:acetate salt is 1:0.5 to 1:2, and wherein a total amount of the acetic acid and acetate salt contained in the dialysis agent A is between 2 mEq/L and 6 mEq/L when the dialysis agent A is dissolved in 1 L of a bicarbonate dialysate.
    Type: Application
    Filed: February 20, 2018
    Publication date: June 21, 2018
    Inventors: Hiroshi NOGUCHI, Michiko MYOSE, Junya KIKUISHI, Mina HASHIMOTO, Hideyuki AOYAMA
  • Patent number: 9931453
    Abstract: The purpose of the present invention is to provide a dialysis agent A, which is able to set the total acetate ion content in the dialysate to a low value, excellent in storage stability of glucose, able to reduce the acetic acid odor, and able to suppress the corrosion of the dialysate delivery system and the dialysis machine, as well as to provide a two pack type dialysis agent utilizing the dialysis agent A. In the dialysis agent A used in the preparation of a bicarbonate dialysate, which is used as one part of a two pack type dialysis agent, it becomes possible to prepare a bicarbonate dialysate having the total acetate ion concentration of between 2 mEq/L or more and less than 6 mEq/L by allowing to include glucose, acetic acid and acetate salt and to satisfy the molar ratio of 1:0.5 to 2 of acetic acid and acetate salt, and include acetic acid and acetate salt in a total amount of between 2 mEq or more and less than 6 mEq in the dialysis agent A required to prepare 1 L of the bicarbonate dialysate.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: April 3, 2018
    Assignee: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Hiroshi Noguchi, Michiko Myose, Junya Kikuishi, Mina Hashimoto, Hideyuki Aoyama
  • Patent number: 9463266
    Abstract: Technology for preparing a dialysis fluid capable of flexibly changing bicarbonate ion concentration and maintaining concentrations of electrolytes such as potassium, calcium, and magnesium at constant levels during dialysis according to the disease state of a patient. A three-component dialysate containing an agent S containing sodium chloride, an agent B containing sodium bicarbonate, and an agent A containing electrolyte components other than sodium chloride and sodium bicarbonate, with suitable adjustment of the amount of the agent B during dialysis fluid preparation maintains concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions in a dialysis fluid at constant levels and flexibly changes the bicarbonate ion concentration therein. Adjusting the ratio between the amount of the agent S and agent B when the dialysate is used also makes it possible to maintain the sodium ion concentration at a constant level or flexibly change the sodium ion concentration.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: October 11, 2016
    Assignee: Tomita Pharmaceuticals Co., Ltd.
    Inventors: Hiroshi Noguchi, Junya Kikuishi, Hideyuki Aoyama, Mina Hashimoto
  • Publication number: 20160235785
    Abstract: [Problem] To provide a solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, which enables the setting of a low total acetate ion content in a dialysis fluid, and which exhibits excellent storage stability of glucose or the like and a reduced acetic acid odor. [Solution] A solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, wherein: the solid dialysis A agent contains glucose, acetic acid and an acetate salt; at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate; and the acetic acid/acetate salt molar ratio is adjusted to 1/0.5 to 1/2. This solid dialysis A agent makes it possible to prepare a bicarbonate dialysis fluid which has a total acetate ion concentration of 2 to less than 6 mEq/L. Further, the dialysis A agent exhibits excellent stability of ingredients and a reduced acetic acid odor.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 18, 2016
    Inventors: Michiko MYOSE, Hiroshi NOGUCHI, Junya KIKUISHI, Hideyuki AOYAMA, Mina HASHIMOTO, Yusuke YOSHIMOTO
  • Publication number: 20140097386
    Abstract: The purpose of the present invention is to provide a dialysis agent A, which is able to set the total acetate ion content in the dialysate to a low value, excellent in storage stability of glucose, able to reduce the acetic acid odor, and able to suppress the corrosion of the dialysate delivery system and the dialysis machine, as well as to provide a two pack type dialysis agent utilizing the dialysis agent A. In the dialysis agent A used in the preparation of a bicarbonate dialysate, which is used as one part of a two pack type dialysis agent, it becomes possible to prepare a bicarbonate dialysate having the total acetate ion concentration of between 2 mEq/L or more and less than 6 mEq/L by allowing to include glucose, acetic acid and acetate salt and to satisfy the molar ratio of 1:0.5 to 2 of acetic acid and acetate salt, and include acetic acid and acetate salt in a total amount of between 2 mEq or more and less than 6 mEq in the dialysis agent A required to prepare 1 L of the bicarbonate dialysate.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 10, 2014
    Applicant: Tomita Pharmaceutical Co., Ltd.,
    Inventors: Hiroshi NOGUCHI, Michiko MYOSE, Junya KIKUISHI, Mina HASHIMOTO, Hideyuki AOYAMA