Patents by Inventor Jurgen Dammgen

Jurgen Dammgen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5175157
    Abstract: Disclosed are new cyclic amine derivatives of the formula I ##STR1## wherein the substituents are defined in the specification. These compounds are useful as for treating sinus tachycardia.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: December 29, 1992
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Manfred Psiorz, Joachim Heider, Andreas Bomhard, Manfred Reiffen, Norbert Hauel, Klaus Noll, Berthold Narr, Christian Lillie, Walter Kobinger, Jurgen Dammgen
  • Patent number: 4871735
    Abstract: The present invention relates to new naphthyl derivatives of general formula ##STR1## wherein N represents the number 1 or 2,A represents a --CH.sub.2 --, --CO--, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## while the atom marked with an x is linked to the phenyl nucleus, E represents a straight chained alkylene group optionally substituted by an alkyl group,G represents a straight chained alkylene group optionally substituted by an alkyl group,L represents a bond or an oxygen atom, if G represents a straight chained alkylene group with 2 to 5 carbon atoms optionally substituted by an alkyl group,R.sub.1 and R.sub.2, which may be identical or different, represent alkyl or alkoxy groups or R.sub.1 and R.sub.2 together represent an alkylenedioxy group,R.sub.3 represents a hydrogen atom, or an alkyl or an allyl group,R.sub.4, R.sub.5 and R.sub.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: October 3, 1989
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Joachim Heider, Manfred Psiorz, Andreas Bomhard, Norbert Hauel, Berthold Narr, Klaus Noll, Christian Lillie, Walter Kobinger, Jurgen Dammgen
  • Patent number: 4154837
    Abstract: Compounds of the formula ##STR1## wherein A is benzo, mono-, di- or tri-substituted benzo, the substituents being selected from the group consisting of lower alkoxy, amino and nitro, or pyrido;R.sub.1 is hydrogen or lower alkyl;R.sub.2 is alkyl of 1 to 6 carbon atoms or --X--R.sub.6,where X is straight alkylene of 1 to 4 carbon atoms or hydroxy-substituted straight alkylene of 1 to 4 carbon atoms; andR.sub.6 is amino; carbalkoxy of 2 to 6 carbon atoms; phenyl; mono-, di- or tri-substituted phenyl, the substituents being selected from the group consisting of lower alkyl and lower alkoxy; phenoxy; or mono-, di- or tri-substituted phenoxy, the substituents being selected from the group consisting of lower alkyl and lower alkoxy;R.sub.3 is hydrogen or hydroxyl;R.sub.4 is hydrogen, lower alkyl or lower alkoxy;R.sub.5 is hydrogen or lower alkyl; andN is 0, 1 or 2;And non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as antiarrhythmics, .beta.
    Type: Grant
    Filed: January 6, 1978
    Date of Patent: May 15, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Joachim Heider, Volkhard Austel, Wolfgang Eberlein, Rudolf Kadatz, Jurgen Dammgen, Walter Kobinger, Christian Lillie
  • Patent number: 4137318
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.6, which may be identical to or different from each other, are each hydrogen or lower alkyl;R.sub.3 is lower alkoxy;R.sub.4 is lower alkoxy or, together with R.sub.3, methylenedioxy or ethylenedioxy;R.sub.5 is hydrogen, lower alkyl or benzyl;R.sub.7 is hydrogen or lower alkoxy;R.sub.8 is hydrogen, lower alkoxy or, together with R.sub.7, methylenedioxy or ethylenedioxy;M is 1 or 2; andN is 2 or 3;And non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antihypertensives and heart rate reducers.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: January 30, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Wolfgang Eberlein, Joachim Heider, Volkhard Austel, Jurgen Dammgen, Rudolf Kadatz
  • Patent number: 4134980
    Abstract: Compounds of the formula ##STR1## wherein A is ##STR2## where R.sub.1 is hydrogen or alkyl of 1 to 3 carbon atoms; R.sub.2 is alkoxy of 1 to 3 carbon atoms;R.sub.3 is alkoxy of 1 to 3 carbon atoms or, together with R.sub.2, methylenedioxy or ethylenedioxy;R.sub.4 is hydrogen, alkyl of 1 to 3 carbon atoms or benzyl;R.sub.5 is hydrogen or alkyl of 1 to 3 carbon atoms;R.sub.6 is hydrogen or alkoxy of 1 to 3 carbon atoms;R.sub.7 is alkoxy of 1 to 3 carbon atoms or, together with R.sub.6, methylenedioxy or ethylenedioxy; andN is 2 or 3;And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as heart rate reducers and mild antihypertensives.This invention relates to novel N-(phenylalkylaminoalkyl)-substituted quinazolinones and phthalazinones and nontoxic acid addition salts thereof, as well as to various methods of preparing these compounds.
    Type: Grant
    Filed: August 24, 1977
    Date of Patent: January 16, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Wolfgang Eberlein, Volkhard Austel, Joachim Heider, Jurgen Dammgen, Rudolf Kadatz, Christian Lillie, Walter Kobinger
  • Patent number: 4087541
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl or phenyl,R.sub.2 is hydrogen, chlorine or methoxy,R.sub.3 is hydrogen or methoxy,R.sub.2 and R.sub.3, together with each other, are methylenedioxy or ethylenedioxy,R.sub.4 and R.sub.5 are each hydrogen or lower alkyl,R.sub.6 is hydrogen or lower alkoxy.R.sub.7 is lower alkoxy,R.sub.6 and R.sub.7, together with each other, are methylenedioxy or ethylenedioxy, andn is 2 or 3,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful for slowing the heart rate.
    Type: Grant
    Filed: May 4, 1977
    Date of Patent: May 2, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Wolfgang Eberlein, Eberhard Kutter, Joachim Heider, Volkhard Austel, Rudolf Kadatz, Willi Diederen, Walter Kobinger, Christian Lillie, Jurgen Dammgen
  • Patent number: 4038407
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl or phenyl,R.sub.2 is hydrogen, chlorine or methoxy,R.sub.3 is hydrogen or methoxy,R.sub.2 and R.sub.3, together with each other, are methylenedioxy or ethylenedioxy,R.sub.4 and R.sub.5 are each hydrogen or lower alkyl,R.sub.6 is hydrogen or lower alkoxy,R.sub.7 is lower alkoxy,R.sub.6 and R.sub.7, together with each other, are methylenedioxy or ethylenedioxy,X is carbonyl or sulfonyl, andn is 2 or 3,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful for slowing the heart rate.
    Type: Grant
    Filed: February 24, 1976
    Date of Patent: July 26, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Wolfgang Eberlein, Eberhard Kutter, Joachim Heider, Volkhard Austel, Rudolf Kadatz, Willi Diederen, Walter Kobinger, Christian Lillie, Jurgen Dammgen