Patents by Inventor Jurgen Stoltefuss

Jurgen Stoltefuss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-HETEROARYL-TETRAHYDROQUINOLINES AND THEIR USE AS INHIBITORS OF THE CHOLESTERIN-ESTER TRANSFER PROTEIN
    Publication number: 20070142420
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Application
    Filed: February 22, 2007
    Publication date: June 21, 2007
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: JURGEN STOLTEFUSS, MICHAEL LOGERS, GUNTER SCHMIDT, ARNDT BRANDES, CARSTEN SCHMECK, KLAUS BREMM, HILMAR BISCHOFF, DELF SCHMIDT
  • Dihydropyrimidines
    Publication number: 20070117812
    Abstract: The invention relates to compounds of the formulae
    Type: Application
    Filed: December 15, 2006
    Publication date: May 24, 2007
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Maria Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • 4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Patent number: 7192971
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: March 20, 2007
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Michael Lörges, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Medicaments against viral diseases
    Patent number: 7074784
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: July 11, 2006
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Maria Niewohner, legal representative, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres, Ulrich Niewohner, deceased
  • 4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Publication number: 20060069112
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Application
    Filed: October 25, 2005
    Publication date: March 30, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuß, Michael Lörges, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • 4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Patent number: 6958346
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: October 25, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Michael Lögers, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Imidazotriazines for use as phosphodiesterase inhibitors
    Patent number: 6936609
    Abstract: The invention relates to new imidazotriazines, processes for their preparation, and their use for the production of medicaments for the treatment and/or prophylaxis of neurodegenerative disorders, in particular Parkinson's disease.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: August 30, 2005
    Assignee: Bayer HealthCare AG
    Inventors: Jens-Kerim Ergüden, Marcus Bauser, Nils Burkhardt, Dietmar Flubacher, Arno Friedl, Irene Gerlach, Volker Hinz, Reinhard Jork, Paul Naab, Maria Theresia Niewöhner, Thorsten Oliver Repp, Karl-Heinz Schlemmer, Jürgen Stoltefuss, David Brückner, Martin Hendrix, Dagmar Schauss, Adrian Tersteegen, Ulrich Niewöhner
  • Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
    Patent number: 6930114
    Abstract: The present invention relates to pyrrolo[2.1-a]dihydroisoquinolines which are inhibitors of phosphodiesterase 10a and can be used for combating cancer.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: August 16, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Maria Theresia Niewöhner, Marcus Bauser, Jens-Kerim Ergüden, Dietmar Flubacher, Paul Naab, Thorsten-Oliver Repp, Jürgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese, Ulrich Niewöhner
  • 4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein
    Patent number: 6897317
    Abstract: The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: May 24, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gunter Schmidt, Jürgen Stoltefuss, Michael Lögers, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • 6-carboxyphenyldihydropyridazinone derivatives and use thereof
    Patent number: 6867206
    Abstract: The present invention relates to 6-carboxyphenyldihydropyridazinone derivatives having the formula wherein R1, R2, R3, A, D, G, and E are as defined in the specification and claims, a process for preparing these materials, pharmaceutical compositions containing them, and a method for using them in the treatment of anemias.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: March 15, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Gabriele Bräunlich, Michael Lögers, Carsten Schmeck, Ulrich Nielsch, Martin Bechem, Christoph Gerdes, Michael Sperzel, Klemens Lustig, Werner Stürmer
  • Imidazotriazines for use as phosphodiesterase inhibitors
    Publication number: 20040249148
    Abstract: The invention relates to new imidazotriazines, processes for their preparation, and their use for the production of medicaments for the treatment and/or prophylaxis of neurodegenerative disorders, in particular Parkinson's disease.
    Type: Application
    Filed: June 25, 2004
    Publication date: December 9, 2004
    Inventors: Jens-Kerim Erguden, Marcus Bauser, Nils Burkhardt, Dietmar Flubacher, Arno Friedl, Irene Gerlach, Volker Hinz, Reinhard Jork, Paul Naab, Ulrich Niewohner, Maria Theresia Niewohner, Thorsten Oliver Repp, Karl-Heinz Schlemmer, Jurgen Stoltefuss, David Bruckner, Martin Hendrix, Dagmar Schauss, Adrian Tersteegen
  • Dihydropyrimidines
    Publication number: 20040167135
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) 1
    Type: Application
    Filed: February 17, 2004
    Publication date: August 26, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
    Publication number: 20040138249
    Abstract: The present invention relates to pyrrolo[2.1-a]dihydroisoquinolines which are inhibitors of phosphodiesterase 10a and can be used for combating cancer.
    Type: Application
    Filed: February 9, 2004
    Publication date: July 15, 2004
    Inventors: Ulrich Niewohner, Maria Theresia Niewohner, Marcus Bauser, Jens-Kerim Erguden, Dietmar Flubacher, Paul Nabb, Thorsten-Oliver Repp, Jurgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese
  • Tetrahydroquinolinyl 6-methyldihydrothiadiazinone derivatives and use thereof
    Patent number: 6699857
    Abstract: The invention relates to the area of erythropoiesis, in particular to the use of tetrahydroquinolinyl-6-methyldihydrothiadiazinones of general formula (I) for treating anaemia. The invention also relates to novel tetrahydroquinolinyl-6-methyldihydrothiadiazinone derivatives and to the production thereof.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: March 2, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Gabriele Bräunlich, Michael Lögers, Carsten Schmeck, Ulrich Nielsch, Martin Bechem, Christoph Gerdes, Michael Sperzel, Klemens Lustig, Werner Stürmer
  • Dihydropyrimidines
    Patent number: 6696451
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) The invention furthermore relates to processes for preparing the compounds of the formulae (I) and (Ia) and to their use as medicaments, in particular for the treatment and prophylaxis of hepatitis B.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: February 24, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Siegfired Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Arnold Paessens, Erwin Graef, Stefan Lettmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Pyrrolo[2.1-a]isoquinoline derivatives
    Publication number: 20030236276
    Abstract: The present invention relates to pyrrolo[2.1-a]isoquinolines which are inhibitors of phosphodiesterase 10a, a process for preparing these compounds and a method of treating cancer in humans and animals by administering these compounds.
    Type: Application
    Filed: August 5, 2002
    Publication date: December 25, 2003
    Inventors: Ulrich Niewohner, Maria Niewohner, Marcus Bauser, Jens-Kerim Erguden, Dietmar Flubacher, Paul Naab, Thorsten-Oliver Repp, Jurgen Stoltefuss, Nils Burkhardt, Andrea Sewing, Michael Schauer, Karl-Heinz Schlemmer, Olaf Weber, Stephen J. Boyer, Mark Miglarese, Jianmei Fan, Barton Phillips, Brian C. Raudenbush, Yamin Wang
  • Medicaments against viral diseases
    Publication number: 20030232842
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Application
    Filed: March 10, 2003
    Publication date: December 18, 2003
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Ulrich Niewohner, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres
  • 4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein
    Publication number: 20030232990
    Abstract: The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.
    Type: Application
    Filed: March 31, 2003
    Publication date: December 18, 2003
    Applicant: Bayer Aktiengesellschaft
    Inventors: Gunter Schmidt, Jurgen Stoltefuss, Michael Logers, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • Substituted tetrahydronaphthaline and analogous compounds
    Patent number: 6586613
    Abstract: Substituted tetrahydro-naphthalenes and analogous compounds are prepared by reducing or condensing appropriate functional substituents in substituted tetrahydro-naphthalenes and analogous compounds by customary methods and converting functional groups in this manner into the desired groups. The compounds according to the invention are suitable for use as active compounds in pharmaceuticals, in particular in pharmaceuticals for treating arteriosclerosis and also dyslipidaemias.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: July 1, 2003
    Assignee: Bayer Aktiengellschaft
    Inventors: Arndt Brandes, Michael Lögers, Jürgen Stoltefuss, Gunter Schmidt, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt, Stefan Antons, Holger Paulsen, Stephan Nicholas Müller, Paul Naab, Carsten Schmeck
  • 4-phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein
    Patent number: 6562976
    Abstract: The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments. for the treatment of arteriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: May 13, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gunter Schmidt, Jürgen Stoltefuss, Michael Lögers, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt