Patents by Inventor Kagari Fujita

Kagari Fujita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endothelin antagonistic peptide derivatives
    Patent number: 5691315
    Abstract: The invention relates to compounds which are antagonists of endothelin, to processes for their preparation, and to their use as pharmaceuticals. The compounds of the invention are Useful in the treatment of hypertension, pulmonary hypertension, Reynaud's disease, myocardial infarction, angina pectoris, acute renal failure, cerebral infarction, cerebral vasospasm, arteriosclerosis, asthma, endotoxin shock, endotoxin-induced multiple organ failure or disseminated intravascular coagulation, and/or cyclosporin-induced renal failure or hypertension.
    Type: Grant
    Filed: June 26, 1995
    Date of Patent: November 25, 1997
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takashi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaki Ihara, Fumihiko Ikemoto, Mitsuo Yano
  • Endothelin antagonistic substance
    Patent number: 5614498
    Abstract: Peptides having the formula: ##STR1## inhibit the binding of endothelin to its ET.sub.B receptor and are useful in treating diseases associated with excess production or secretion of endothelin.
    Type: Grant
    Filed: September 16, 1992
    Date of Patent: March 25, 1997
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takeshi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaki Ihara, Fumihiko Ikemoto, Mitsuo Yano, Masaru Nishikibe
  • Endothelin antagonistic substance
    Patent number: 5496928
    Abstract: Peptides having the formula: ##STR1## inhibit the binding of endothelin and are useful in treating diseases associated with excess production or secretion of endothelin.
    Type: Grant
    Filed: April 20, 1994
    Date of Patent: March 5, 1996
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takashi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaki Ihara, Fumihiko Ikemoto, Mitsuo Yano, Masaru Nishikibe
  • Endothelin antagonistic peptide derivatives
    Patent number: 5470833
    Abstract: Peptides having the formula: ##STR1## inhibit the binding of endothelin to its receptor and are useful in treating diseases associated with excess production or secretion of endothelin.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: November 28, 1995
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takashi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaki Ihara, Fumihiko Ikemoto, Mitsuo Yano
  • Endothelin antagonistic peptide derivatives
    Patent number: 5444152
    Abstract: Peptides having the formula ##STR1## inhibit the binding of endothelin to its receptor and are useful in treating diseases associated with excess production or secretion of endothelin.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: August 22, 1995
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takashi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaki Ihara, Fumihiko Ikemoto, Mitsuo Yano
  • Endothelin antagonistic cyclic pentapeptides
    Patent number: 5114918
    Abstract: Cyclic pentapeptides of the formula:cyclo (-X.sup.1 -X.sup.2 -X.sup.3 -X.sup.4 -X.sup.5 -) (I)wherein X.sup.n (n=1-5) represents amino acid residues. These compounds are useful as hypotensive drugs.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: May 19, 1992
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Kiyofumi Ishikawa, Takehiro Fukami, Takashi Hayama, Kenji Niiyama, Toshio Nagase, Toshiaki Mase, Kagari Fujita, Masaru Nishikibe, Masaki Ihara, Mitsuo Yano
  • Cyclohexane derivatives
    Patent number: 4579971
    Abstract: A cyclohexane derivative having the formula ##STR1## wherein X is 2-(ethylthio)propyl or 2-(4-chlorophenylthio)ethyl.
    Type: Grant
    Filed: March 25, 1985
    Date of Patent: April 1, 1986
    Assignee: Nippon Soda Co. Ltd.
    Inventors: Isao Iwataki, Kagari Fujita, Hisao Ishikawa, Hideo Hosaka, Kenichi Kohara
  • Cyclohexane derivatives
    Patent number: 4515729
    Abstract: A cyclohexane derivative having the formula ##STR1## wherein R.sub.1 is C.sub.1-4 alkyl or halo phenyl;R.sub.2 is C.sub.1-3 alkyl or cyano group;R.sub.3 is C.sub.1-4 alkyl;R.sub.4 is C.sub.1-4 alkyl or C.sub.1-4 alkenyl;X is straight or branched chain C.sub.1-4 alkylene; andn is 0, 1 or 2,which possess herbicidal properties, and the process for its preparation.
    Type: Grant
    Filed: January 26, 1983
    Date of Patent: May 7, 1985
    Assignee: Nippon Soda Company Limited
    Inventors: Isao Iwataki, Kagari Fujita, Hisao Ishikawa, Hideo Hosaka, Kenichi Kohara