Patents by Inventor Kap-Sun Yeung

Kap-Sun Yeung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS
    Publication number: 20100210599
    Abstract: This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.
    Type: Application
    Filed: April 26, 2010
    Publication date: August 19, 2010
    Inventors: Yasutsugu Ueda, Timothy P. Connolly, John F. Kadow, Nicholas A. Meanwell, Tao Wang, Chung-Pin H. Chen, Kap-Sun Yeung, Zhongxing Zhang, David Kenneth Leahy, Shawn K. Pack, Nachimuthu Soundararajan, Pierre Sirard, Kathia Levesque, Dominique Thoraval
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20100184800
    Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: March 9, 2010
    Publication date: July 22, 2010
    Inventors: Richard Pracitto, John F. Kadow, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, Andrew Nickel, Kyle E. Parcella, Kap-Sun Yeung, Louis S. Chupak
  • Prodrugs of piperazine and substituted piperidine antiviral agents
    Patent number: 7745625
    Abstract: This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: June 29, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yasutsugu Ueda, Timothy P. Connolly, John F. Kadow, Nicholas A. Meanwell, Tao Wang, Chung-Pin H. Chen, Kap-Sun Yeung, Zhongxing Zhang, David Kenneth Leahy, Shawn K. Pack, Nachimuthu Soundararajan, Pierre Sirard, Kathia Levesque, Dominique Thoraval
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20100093694
    Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: September 4, 2009
    Publication date: April 15, 2010
    Inventors: Kap-Sun Yeung, Kyle E. Parcella, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, John F. Kadow, Andrew Nickel
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20100063068
    Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 11, 2010
    Inventors: Richard Pracitto, John F. Kadow, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, Andrew Nickel, Kyle E. Parcella, Kap-Sun Yeung, Louis S. Chupak
  • Compounds for the treatment of hepatitis C
    Patent number: 7652004
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: January 26, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20090275561
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: February 11, 2009
    Publication date: November 5, 2009
    Inventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
  • Compounds for the treatment of Hepatitis C
    Patent number: 7547690
    Abstract: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: June 16, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the treatment of hepatitis C
    Patent number: 7541353
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: June 2, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the treatment of hepatitis C
    Patent number: 7541352
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: June 2, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, John F. Kadow, Katharine A. Grant-Young
  • Compounds for the treatment of Hepatitis C
    Patent number: 7538102
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: May 26, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, John A. Bender, Robert G. Gentles, Zhong Yang, Min Ding, Yong Tu, Piyasena Hewawasam, Ying Han, John F. Kadow
  • Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
    Patent number: 7521441
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: April 21, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Piyasena Hewawasam, Min Ding, Carl P. Bergstrom, Scott W. Martin, Kap-Sun Yeung, Thomas W. Hudyma, Xiaofan Zheng, John A. Bender, John F. Kadow
  • Compounds for the treatment of hepatitis C
    Patent number: 7521444
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: April 21, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: John A. Bender, Robert G. Gentles, Ying Han, Yong Tu, Zhong Yang, Kap-Sun Yeung, Katharine A. Grant-Young
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20090074715
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: July 28, 2008
    Publication date: March 19, 2009
    Inventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
  • Indolobenzazepine HCV NS5B inhibitors
    Patent number: 7473688
    Abstract: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: January 6, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Carl P. Bergstrom, John A. Bender, Robert G. Gentles, Piyasena Hewawasam, Thomas W. Hudyma, John F. Kadow, Scott W. Martin, Alicia Regueiro-Ren, Kap-Sun Yeung, Yong Tu, Katharine A. Grant-Young, Xiaofan Zheng
  • Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
    Patent number: 7452876
    Abstract: The invention encompasses compounds as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: November 18, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, Katharine A. Grant-Young, Min Ding, Robert G. Gentles, John F. Kadow
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080227769
    Abstract: The invention encompasses compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using these compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: February 28, 2008
    Publication date: September 18, 2008
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226592
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: Kap-Sun Yeung, John A. Bender, Robert G. Gentles, Zhong Yang, Min Ding, Yong Tu, Piyasena Hewawasam, Ying Han, John F. Kadow
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226590
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: John A. Bender, Robert G. Gentles, Ying Han, Yong Tu, Zhong Yang, Kap-Sun Yeung, Katharine A. Grant-Young
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20080226591
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 18, 2008
    Inventors: Robert G. Gentles, Xiaofan Zheng, Min Ding, Yong Tu, Ying Han, Piyasena Hewawasam, John F. Kadow, John A. Bender, Kap-Sun Yeung, Katharine A. Grant-Young, Thomas W. Hudyma