Patents by Inventor Kara Podkaminer

Kara Podkaminer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10066217
    Abstract: Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of Thermoanaerobacterium saccharolyticum with acetate kinase and phosphotransacetylase expression eliminated are disclosed herein. Further, strain ALK1 has been engineered by site directed homologous recombination to knockout both acetic acid and lactic acid production. Continuous culture involving a substrate concentration challenge lead to evolution of ALK1, and formation of a more robust strain designated ALK2. The organisms may be utilized for example in thermophilic SSF and SSCF reactions performed at temperatures that are optimal for cellulase activity to produce near theoretical ethanol yields without expressing pyruvate decarboxylase.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: September 4, 2018
    Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Arthur Josephus Shaw, IV, Sunil G. Desai, Lee R. Lynd, Kara Podkaminer, John Bardsley, David Anthony Hogsett
  • Patent number: 10036051
    Abstract: Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: July 31, 2018
    Assignee: Alliance for Sustainable Energy, LLC
    Inventors: William S. Adney, Gregg T. Beckham, Eric Jarvis, Michael E. Himmel, Stephen R. Decker, Jeffrey G. Linger, Kara Podkaminer, John O. Baker, Larry Taylor, II, Qi Xu, Arjun Singh
  • Publication number: 20170247731
    Abstract: Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
    Type: Application
    Filed: May 12, 2017
    Publication date: August 31, 2017
    Inventors: William S. ADNEY, Gregg T. BECKHAM, Eric JARVIS, Michael E. HIMMEL, Stephen R. DECKER, Jeffrey G. LINGER, Kara PODKAMINER, John O. BAKER, Larry TAYLOR, II, Qi XU, Arjun SINGH
  • Patent number: 9683248
    Abstract: Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: June 20, 2017
    Assignee: Alliance for Sustainable Energy, LLC
    Inventors: William S. Adney, Gregg T. Beckham, Eric Jarvis, Michael E. Himmel, Stephen R. Decker, Jeffrey G. Linger, Kara Podkaminer, John O. Baker, Larry Taylor, II, Qi Xu, Arjun Singh
  • Publication number: 20140322765
    Abstract: Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
    Type: Application
    Filed: December 17, 2012
    Publication date: October 30, 2014
    Inventors: William S. Adney, Gregg T. Beckham, Eric Jarvis, Michael E. Himmel, Stephen R. Decker, Jeffrey G. Linger, Kara Podkaminer, John O. Baker, Larry Taylor, II, Qi Xu, Arjun Singh
  • Publication number: 20120077239
    Abstract: Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of Thermoanaerobacterium saccharolyticum with acetate kinase and phosphotransacetylase expression eliminated are disclosed herein. Further, strain ALK1 has been engineered by site directed homologous recombination to knockout both acetic acid and lactic acid production. Continuous culture involving a substrate concentration challenge lead to evolution of ALK1, and formation of a more robust strain designated ALK2. The organisms may be utilized for example in thermophilic SSF and SSCF reactions performed at temperatures that are optimal for cellulase activity to produce near theoretical ethanol yields without expressing pyruvate decarboxylase.
    Type: Application
    Filed: May 1, 2007
    Publication date: March 29, 2012
    Inventors: Arthur Josephus Shaw, IV, Sunil G. Desai, Lee R. Lynd, Mikhail V. Tyurin, Kara Podkaminer, John Bardsley, David Anthony Hogsett
  • Publication number: 20090221049
    Abstract: Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of Thermoanaerobacterium saccharolyticum with acetate kinase and phosphotransacetylase expression eliminated are disclosed herein. Further, strain ALK1 has been engineered by site directed homologous recombination to knockout both acetic acid and lactic acid production. Continuous culture involving a substrate concentration challenge lead to evolution of ALK1, and formation of a more robust strain designated ALK2. The organisms may be utilized for example in thermophilic SSF and SSCF reactions performed at temperatures that are optimal for cellulase activity to produce near theoretical ethanol yields without expressing pyruvate decarboxylase.
    Type: Application
    Filed: May 1, 2007
    Publication date: September 3, 2009
    Inventors: Arthur Josephus Shaw, IV, Sunil G. Desai, Lee R. Lynd, Mikhail V. Tyurin, Kara Podkaminer, John Bardsley, David Anthony Hogsett