Patents by Inventor Karen Biscardi

Karen Biscardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunological combination compositions and methods
    Publication number: 20080089911
    Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Application
    Filed: May 18, 2007
    Publication date: April 17, 2008
    Inventors: Robert Becker, Robert Huebner, Maryann Gray, Karen Biscardi, Lorne Erdile, Bruno Guy
  • Immunological combination compositions and methods
    Publication number: 20060110408
    Abstract: Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
    Type: Application
    Filed: July 1, 2005
    Publication date: May 25, 2006
    Inventors: Robert Becker, Robert Huebner, Maryann Gray, Karen Biscardi, Lorne Erdile, Bruno Guy
  • Potentiation of immunogenic response
    Patent number: 6024963
    Abstract: An enhanced immune response to antigens, particularly normally weakly-immunogenic viral antigens, such as the HA antigen from influenza virus, is achieved by coadministering the antigen in two different physio-chemical forms, particularly to enable presentation of antigen both by B cells and accessory cells.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: February 15, 2000
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Karen Biscardi, Laura Ferguson, Lorne Erdile
  • Potentiation of immunogenic response
    Patent number: 5853736
    Abstract: An enhanced immune response to antigens, particularly normally weakly-immunogenic viral antigens, such as the HA antigen from influenza virus, is achieved by coadministering the antigen in two different physiochemical forms, particularly to enable presentation of antigen both by B cells and accessory cells.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: December 29, 1998
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Karen Biscardi, Laura Ferguson, Lorne Erdile
  • Potentiation of immunogenic response
    Patent number: 5837264
    Abstract: An enhanced immune response to antigens, particularly normally weakly-immunogenic viral antigens, such as the HA antigen from influenza virus, is achieved by coadministering the antigen in two different physio-chemical forms, particularly to enable presentation of antigen both by B cells and accessory cells.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 17, 1998
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Karen Biscardi, Laura Ferguson, Lorne Erdile
  • Potentiation of immunogenic response
    Patent number: 5662909
    Abstract: An enhanced immune response to antigens, particularly normally weakly-immunogenic viral antigens, such as the HA antigen from influenza virus, is achieved by coadministering the antigen in two different physio-chemical forms, particularly to enable presentation of antigen both by B cells and accessory cells.
    Type: Grant
    Filed: February 8, 1995
    Date of Patent: September 2, 1997
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Karen Biscardi, Laura Ferguson, Lorne Erdile
  • Test for determining the dose response of a conjugated vaccine
    Patent number: 5604108
    Abstract: The dosage response of humans to conjugate vaccines comprising a bacterial polysaccharide and a strongly-immunogenic carrier protein is determined in animals by coadministering to the animal unconjugated strongly-immunogenic carrier protein in an amount corresponding, on a weight-related basis, to that administered to the human.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: February 18, 1997
    Assignee: Connaught Laboratories, Inc.
    Inventors: Robert S. Becker, Karen Biscardi, Patrick McVerry, Robert Ryall