Patents by Inventor Karen Slobod

Karen Slobod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210162037
    Abstract: The present invention relates to mRNA sequences usable as mRNA-based vaccines against infections with influenza viruses. Additionally, the present invention relates to a composition comprising the mRNA sequences and the use of the mRNA sequences or the composition for the preparation of a pharmaceutical composition, especially a vaccine, e.g. for use in the prophylaxis or treatment of influenza virus infections. The present invention further describes a method of treatment or prophylaxis of infections with influenza virus using the mRNA sequences.
    Type: Application
    Filed: May 4, 2017
    Publication date: June 3, 2021
    Inventors: Edith JASNY, Susanne RAUCH, Kim Ellen SCHWENDT, Benjamin PETSCH, Karen SLOBOD
  • Patent number: 10329584
    Abstract: The present invention relates to a Sendai virus or recombinant Sendai virus vector. In particular the present invention provides methods, vectors, formulations, compositions, and kits for a modified Enders strain Sendai viral vector. An immunogenic vector can be used in any in vitro or in vivo system. Moreover, some embodiments include vectors for imaging virus growth, location and transmission.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: June 25, 2019
    Assignee: St. Jude Children's Research Hospital
    Inventors: Julia Lea Hurwitz, Toru Takimoto, Charles John Russell, Allen Portner, Karen Slobod
  • Publication number: 20170321224
    Abstract: The present invention relates to a Sendai virus or recombinant Sendai virus vector. In particular the present invention provides methods, vectors, formulations, compositions, and kits for a modified Enders strain Sendai viral vector. An immunogenic vector can be used in any in vitro or in vivo system. Moreover, some embodiments include vectors for imaging virus growth, location and transmission.
    Type: Application
    Filed: February 28, 2017
    Publication date: November 9, 2017
    Inventors: Julia Lea Hurwitz, Toru Takimoto, Charles John Russell, Allen Portner, Karen Slobod
  • Patent number: 9637758
    Abstract: The present invention relates to a Sendai virus or recombinant Sendai virus vector. In particular the present invention provides methods, vectors, formulations, compositions, and kits for a modified Enders strain Sendai viral vector. An immunogenic vector can be used in any in vitro or in vivo system. Moreover, some embodiments include vectors for imaging virus growth, location and transmission.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: May 2, 2017
    Assignee: St. Jude Children's Research Hospital
    Inventors: Julia Lea Hurwitz, Toru Takimoto, Charles John Russell, Allen Portner, Karen Slobod
  • Publication number: 20140186397
    Abstract: The present invention relates to a Sendai virus or recombinant Sendai virus vector. In particular the present invention provides methods, vectors, formulations, compositions, and kits for a modified Enders strain Sendai viral vector. An immunogenic vector can be used in any in vitro or in vivo system. Moreover, some embodiments include vectors for imaging virus growth, location and transmission.
    Type: Application
    Filed: April 13, 2012
    Publication date: July 3, 2014
    Inventors: Julia Lea Hurwitz, Toru Takimoto, Charles John Russell, Allen Portner, Karen Slobod
  • Publication number: 20060110740
    Abstract: Immunogenic compositions to protect against human parainfluenza (hPIV) virus infection are provided. The compositions comprise an unmodified Sendai virus that can be safely administered to human subjects, particularly young children, to protect against symptoms and health risks associated with hPIV infection.
    Type: Application
    Filed: January 12, 2004
    Publication date: May 25, 2006
    Inventors: Julia Hurwitz, Christopher Coleclough, Karen Slobod, Allen Portner
  • Patent number: 6723558
    Abstract: Polyenv vaccines are provided that comprise mixtures of at least 4 to about 10,000 different recombinant viruses that each express a different HIV env variant or a portion thereof containing both constant and variable regions, as well as methods of making and using such polyenv vaccines and viruses, including the use of the polyenv vaccine, in live, attenuated or inactivated form, for prophylaxis or treatment of HIV infection. The viral vaccines of the invention are optimally combined with a recombinant HIV env booster, or a recombinant HIV env gene DNA priming or boosting vaccine.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: April 20, 2004
    Assignee: St. Jude Children's Research Hospital
    Inventors: Julia Hurwitz, Christopher Coleclough, Randall Owens, Karen Slobod
  • Patent number: 5846546
    Abstract: Polyenv immunogenic composition are provided that comprise mixtures of at least 4 different recombinant viruses that each express a different HIV env variant or a portion thereof containing both constant and variable regions, as well as methods of making and using such polyenv immunogenic composition and viruses. The immunogenic composition of the invention are optimally combined with a recombinant HIV env booster, or a recombinant HIV env gene DNA priming or boosting vaccine.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: December 8, 1998
    Assignee: St. Jude Children's Research Hospital
    Inventors: Julia Hurwitz, Karen Slobod