Patents by Inventor Karl-Dieter Entian

Karl-Dieter Entian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060078901
    Abstract: The genome sequence and nucleotide sequences of Listeria monocytogenes EGD-e are provided. Polypeptide sequences, including surface or cell envelope polypeptides, and polypeptides involved in metabolism, including B12 biosynthesis, are also provided. Uses of these sequences are also provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: April 13, 2006
    Inventors: Carmen Buchrieser, Lionel Frangeul, Elisabeth Couve, Christophe Rusniok, Hafida Fsihi, Pierre Dehoux, Olivier Dussurget, Farid Chetouani, Hafed Nedjari, Philippe Glaser, Franck Kunst, Pascale Cossart, Justin Daniels, Werner Goebei, Jurgen Kreft, Michael Kuhn, Eva Ng, Jose Vazquez-Boland, Gustavo Dominguez-Bernal, Patricia Garrido-Garcia, Alberto Tierrez-Martinez, Alexandra Amend, Trinad Chakraborty, Eugen Domann, Thorsten Hain, Patrick Berche, Alain Charbit, Lionel Durant, Jose-Claudio Perez-Diaz, Fernando Baquero, Francisco Garcia Del Portillo, Nuria Gomez-Lopez, Encarna Maduenio, Betriz de Pablos, Jurgen Wehland, Uwe Karst, Karl-Dieter Entian, Jorg Hauf, Matthias Rose, Hamut Voss
  • Publication number: 20040229276
    Abstract: The present invention concerns a method for the screening of antimycotic substances wherein an essential gene from mycetes or a functionally similar mycete gene, or the corresponding encoded protein, is used as target and wherein the essential gene is selected from the group consisting in YML114c, YLR186w, YLR215c, YLR222c, YLR243w, YLR272c, YLR275w, YLR276c, YLR317w, YLR359w, YLR373c, YLR424w, YLR437c, YLR440c, YML023c, YML049c, YML077w, YML093w, YML127w, YMR032w, YMR093w, YMR131c, YMR185w, YMR212c, YMR213w, YMR218c, YMR281w, YMR288w, YMR290c, YMR211w, YMR049c, YMR134w, YDR196c, YDR299w, YDR365c, YDR396w, YDR407c, YDR416w, YDR449c, YDR472w, YDR499w, YDR141c, YDR324c, YDR325w, YDR398w, YDR246w, YDR236c, YDR361c, YDR367w, YDR339c, YDR413c, YDR429c, YDR468c, YDR489w, YDR527w, YDR288w, YDR201w, YDR434w, YDR181c, YDR531w, YPL126w, YPL093w, YPL063w, YPL024w, YPL020c, YPL012w, YPL007c, YPL233w, YPLI46c, YIL091c, YIL083c, YIL019w, YIL109c, YIL104c, YFL024c, YFR003c, YFR027w, YFR042w, YIR010w, YIR015w, YPR048w, YPR07
    Type: Application
    Filed: June 21, 2004
    Publication date: November 18, 2004
    Applicant: Hoechst Marion Roussel
    Inventors: Anita Diu-Hercend, Karl-Dieter Entian, Peter Koetter
  • Patent number: 6537767
    Abstract: The invention relates to a process for screening antimycotically active substances, in which process essential mycete genes, in particular Saccharomyces cerevisae genes and functionally homologous and/or sequentially homologous mycete genes, are employed as targets. A process for finding antimycotically active substances, wherein essential mycete genes are employed as targets.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: March 25, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Albert Hinnen, Johannes Hegemann, Thomas Munder, Tillman Schuster, Horst Feldmann, Wilfried Kramer, Friedrich Karl Zimmermann, Karl-Dieter Entian, Matthias Rose, Peter K├Âtter
  • Patent number: 5843709
    Abstract: A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described.Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 1998
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Karl-Dieter Entian, Friedrich Gotz, Norbert Schnell, Johannes Augustin, Germar Engelke, Ralf Rosenstein, Cortina Kaletta, Cora Klein, Bernd Wieland, Thomas Kupke, Gunther Jung, Roland Kellner
  • Patent number: 5837485
    Abstract: A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described.Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: November 17, 1998
    Assignee: Dr. Karl Tomae GmbH
    Inventors: Karl-Dieter Entian, Friedrich Gotz, Norbert Schnell, Johannes Augustin, Germar Engelke, Ralf Rosenstein, Cortina Kaletta, Cora Klein, Bernd Wieland, Thomas Kupke, Gunther Jung, Roland Kellner