Abstract: The invention relates to a process for producing formulations of sparingly water-soluble substances, said sparingly soluble substances being present in amorphous embedded form in a copolymer, and said copolymer being obtained by free-radically initiated polymerization of a mixture of i) 30 to 80% by weight of N-vinyllactam, ii) 10 to 50% by weight of vinyl acetate, and iii) 10 to 50% by weight of a polyether, with the proviso that the sum of components i), ii) and iii) equals 100% by weight, which comprises embedding the sparingly soluble substance into the copolymer at temperatures above the melting point of the sparingly soluble substances.

Abstract: Process for the production of nanoporous foamed active substance-containing preparations, wherein the active substance is present embedded in a pharmaceutically acceptable polymer, wherein, in stage a) loading of a polymeric molding composition or a polymer melt with a propellant is effected at a pressure and at a temperature at which the propellant is in the supercritical state, in stage b) heating of the laden polymer molding compound or melt is carried out under pressure at a temperature which lies in the range from ?40 to +60° C., preferably ?20 to +55° C., and especially preferably 0 to +50° C. around the glass transition temperature of the unladen (prior to loading) polymeric molding compound and in stage c) a depressurization of the polymeric molding compound or melt laden in stage a) and heated under pressure in stage b) is effected out with a depressurization rate in the range from 15,000 to 200,000 MPa/sec.

Abstract: Preparations with enlarged surface comprising an active ingredient and an amphiphilc copolymer, wherein the copolymer comprises at least one polyether-containing graft polymer. The preparations are partially or completely foamed. Processes for producing the preparations are also described, including processes comprising extrusion of a melt impregnated with a physiologically acceptable volatile blowing agent.

Abstract: The present invention relates to a method for producing N-vinyl pyrrolidone/vinyl acetate copolymers that are soluble in water and that at the same time have a relatively high molecular weight, and to the aqueous polymer solutions and copolymers obtained by way of said method.

Abstract: Use of water-soluble or water-dispersible copolymers which are obtained by polymerization of vinyl acetate and N-vinyllactams in the presence of a polyether, as stabilizing agents for emulsions.

Abstract: Process for the preparation of low-peroxide polymer comprising the treatment of the polymer with elemental metal in the presence of a liquid, polymer obtainable by this process, the use thereof, and also drugs comprising this polymer.

Abstract: Formulations of sparingly water-soluble active ingredientscomprising carrier particles provided with active ingredient-containing coatings, the sparingly soluble active ingredients being embedded in coatings composed of amphiphilic copolymers, and the coatings being applied in the form of a solvent-free melt.

Abstract: A process for producing solid oral dosage forms with controlled active ingredient release, comprising a mixture of a) at least one active ingredient, and b) a preformulated mixture of polyvinyl acetate and polyvinylpyrrolidone, wherein the mixture is obtained by joint processing of components a) and b) in an extruder at temperatures between 50° and 200° C.

Abstract: The use of water-soluble or water-dispersible copolymers which are obtained by free radical-initiated polymerization of a mixture of i) 30 to 80% by weight N-vinyllactam, ii) 10 to 50% by weight vinylacetate and iii) 10 to 50% by weight of a polyether, with the proviso that the total of i), ii) and iii) is equal to 100% by weight, as binders for producing solid active ingredient-containing dosage forms.

Abstract: The present invention relates to a polymeric composition for coating solid substrates (S) consisting of: a) 0.5-90% by weight of polyethylene glycol with a weight-average molecular weight in the range from 1500 to 20 000 g/mol (component A), b) 0.5-20% by weight of a water-soluble polyvinylpyrrolidone with a Fikentscher K value in the range from 12 to 90 (component B), c) 0-95% by weight of a solvent (L), and d) 0-70% by weight of one or more non-polymeric aids (component C).

Abstract: The present invention relates to a process for preparing an aqueous polymer dispersion by free-radical emulsion polymerization of a monomer mixture which comprises N,N-diethylaminoethyl methacrylate, to the polymer dispersion obtainable by this process, and to the use thereof.

Abstract: A process for producing gelatin-free soft capsule shells based on polyvinyl alcohol-polyether graft copolymers as shell polymers, which comprises heating an aqueous solution comprising at least 45% by weight, based on the total weight of the solution, of a polymer component, where the polymer component consists of a polyvinyl alcohol-polyether graft copolymer or a mixture of polyvinyl alcohol-polyether graft copolymers and polyvinyl alcohol, extruding the solution at a temperature of at least 70° C., and solidifying the resulting film by cooling.

Abstract: Polymeric water-soluble salts of medicaments that are sparingly soluble in water, consisting of a polymer with anion character that is soluble in water at pH values of 2-13 and a sparingly soluble medicament with cation character.

Abstract: The present invention relates to pharmaceutical formulations for the production of chewable and suckable tablets, comprising agglomerates based on sugar or sugar alcohols and disintegrant and water-insoluble polymers in combination with a viscosity-increasing/gel-forming polymer, and the corresponding chewable and suckable tablets.

Abstract: Pharmaceutical formulation in the form of agglomerates comprising A) an excipient content composed of a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of a disintegrant, selected from the group consisting of croscarmellose, sodium carboxymethylstarch and L-hydroxypropoylcellulose, c) 1-15% by weight of water-insoluble, film-forming polymers d) 0-15% by weight of water-soluble polymers and e) 0-15% by weight of further pharmaceutically customary excipients the total of the components a) to e) being 100% by weight.

Abstract: Pharmaceutical formulation in the form of agglomerates comprising A) an excipient content composed of a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of a disintegrant, c) 1-15% by weight of water-insoluble, film-forming polymers d) 0-15% by weight of water-soluble polymers and e) 0-15% by weight of further pharmaceutically customary excipients the total of the components a) to e) being 100% by weight, and B) at least one active ingredient.

Abstract: Pharmaceutical formulation in the form of compacts comprising A) an agglomerated excipient content composed of a1) 60-97% by weight of sugar or sugar alcohols, a2) 1-25% by weight of a disintegrant, selected from the group consisting of crospovidone, croscarmellose, sodium carboxymethylstarch and L-hydroxypropylcellulose, a3) 1-15% by weight of water-insoluble, film-forming polymers a4) 0-15% by weight of water-soluble polymers and a5) 0-15% by weight of further pharmaceutically customary excipients, the total of the components a1) to a5) being 100% by weight, B) at least one active ingredient, C) 0 to 10% by weight, based on the total amount of A) to D), of a lubricant or mold release agent, and D), if appropriate, further pharmaceutical excipients.

Abstract: The present invention relates to a method for the production of solid solutions of sparingly soluble pesticides, pulverulent products that are obtained by said method and their use for pesticide formulations.

Abstract: Solid particulate film-coating compositions consisting of a) 40-90% by weight, preferably 40 to 70% by weight, of a polyvinyl alcohol-polyether graft copolymer (component A), b) 10 to 60% by weight, preferably 20 to 45% by weight, of a chromatic or achromatic colorant (component B) c) 0 to 30% by weight of further conventional auxiliaries (component C) where the amount of components A to C adds up to 100% by weight, which are obtained by extrusion of a melt of components A) to C) and subsequent shaping.

Abstract: Described are a method of killing microorganisms in aqueous industrial systems or products for industrial applications based on water by adding from 0.001 to 5% by weight of a water-soluble or water-dispersible polymer containing from 30 to 100 mol % of styrenesulfonic acid, from 0 to 40 mol % of an N-vinyllactam and/or N-vinylamine, and from 0 to 30 mol % of further free-radically polymerizable monomers as biocidal additive, and a method of protecting articles by applying an antimicrobial aqueous composition comprising such an additive.