Patents by Inventor Karl Maurer
Karl Maurer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11936038Abstract: An anode active material for lithium ion batteries includes one or more unaggregated silicon particles having a mass-based chlorine content of from 5 to 200 ppm and a volume-weighted particle size distribution having diameter percentiles d50 of from 0.5 ?m to 10.0 ?m.Type: GrantFiled: October 2, 2018Date of Patent: March 19, 2024Assignee: Wacker Chemie AGInventors: Jürgen Pfeiffer, Eckhard Hanelt, Harald Hertlein, Karl Hesse, Robert Maurer
-
Publication number: 20210395906Abstract: There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.Type: ApplicationFiled: August 24, 2021Publication date: December 23, 2021Inventors: Karl Maurer, John J. Cooper, JR.
-
Patent number: 11185838Abstract: There is disclosed an electrode array architecture employing continuous and discontinuous circumferential electrodes. There is further disclosed a process for the neutralization of acid generated at anode(s) by base generated at cathode(s) circumferentially located to each other so as to confine a region of pH change. The cathodes can be displayed as concentric rings (continuous) or as counter electrodes in a cross pattern (discontinuous). In this way reagents, such as acid, generated in a center electrode are countered (neutralized) by reagents, such as base, generated at the corners or at the outer ring.Type: GrantFiled: November 30, 2019Date of Patent: November 30, 2021Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J Cooper, Jr., H Sho Fuji, Joseph Leonetti
-
Patent number: 10724143Abstract: There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.Type: GrantFiled: June 22, 2018Date of Patent: July 28, 2020Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J. Cooper
-
Publication number: 20200086290Abstract: There is disclosed an electrode array architecture employing continuous and discontinuous circumferential electrodes. There is further disclosed a process for the neutralization of acid generated at anode(s) by base generated at cathode(s) circumferentially located to each other so as to confine a region of pH change. The cathodes can be displayed as concentric rings (continuous) or as counter electrodes in a cross pattern (discontinuous). In this way reagents, such as acid, generated in a center electrode are countered (neutralized) by reagents, such as base, generated at the corners or at the outer ring.Type: ApplicationFiled: November 30, 2019Publication date: March 19, 2020Applicant: CUSTOMARRAY, INC.Inventors: Karl Maurer, John J Cooper, JR., H Sho Fujii, Joseph Leonetti
-
Patent number: 10525436Abstract: There is disclosed an electrode array architecture employing continuous and discontinuous circumferential electrodes. There is further disclosed a process for the neutralization of acid generated at anode(s) by base generated at cathode(s) circumferentially located to each other so as to confine a region of pH change. The cathodes can be displayed as concentric rings (continuous) or as counter electrodes in a cross pattern (discontinuous). In this way reagents, such as acid, generated in a center electrode are countered (neutralized) by reagents, such as base, generated at the corners or at the outer ring.Type: GrantFiled: July 13, 2016Date of Patent: January 7, 2020Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J Cooper, Jr., H Sho Fujii, Joseph Leonetti
-
Publication number: 20190227060Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.Type: ApplicationFiled: March 31, 2019Publication date: July 25, 2019Applicant: CustomArray, Inc.Inventors: Karl Maurer, Dominic Suciu, Hetian Gao
-
Patent number: 10261075Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.Type: GrantFiled: May 25, 2018Date of Patent: April 16, 2019Assignee: CustomArray, Inc.Inventors: Karl Maurer, Dominic Suciu, Hetian Gao
-
Publication number: 20180267032Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.Type: ApplicationFiled: May 25, 2018Publication date: September 20, 2018Applicant: CustomArray, Inc.Inventors: Karl Maurer, Dominic Suciu, Hetian Gao
-
Patent number: 10006131Abstract: There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.Type: GrantFiled: February 22, 2016Date of Patent: June 26, 2018Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J. Cooper, Jr.
-
Patent number: 9983204Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.Type: GrantFiled: April 27, 2009Date of Patent: May 29, 2018Assignee: CustomArray, Inc.Inventors: Karl Maurer, Dominic Suciu, Hetian Gao
-
Publication number: 20160354751Abstract: There is disclosed an electrode array architecture employing continuous and discontinuous circumferential electrodes. There is further disclosed a process for the neutralization of acid generated at anode(s) by base generated at cathode(s) circumferentially located to each other so as to confine a region of pH change. The cathodes can be displayed as concentric rings (continuous) or as counter electrodes in a cross pattern (discontinuous). In this way reagents, such as acid, generated in a center electrode are countered (neutralized) by reagents, such as base, generated at the corners or at the outer ring.Type: ApplicationFiled: July 13, 2016Publication date: December 8, 2016Applicant: CUSTOMARRAY, INC.Inventors: Karl Maurer, John J Cooper, Jr., H Sho Fujii, Joseph Leonetti
-
Patent number: 9394167Abstract: There is disclosed an electrode array architecture employing continuous and discontinuous circumferential electrodes. There is further disclosed a process for the neutralization of acid generated at anode(s) by base generated at cathode(s) circumferentially located to each other so as to confine a region of pH change. The cathodes can be displayed as concentric rings (continuous) or as counter electrodes in a cross pattern (discontinuous). In this way reagents, such as acid, generated in a center electrode are countered (neutralized) by reagents, such as base, generated at the corners or at the outer ring.Type: GrantFiled: April 15, 2005Date of Patent: July 19, 2016Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J. Cooper, Jr., H. Sho Fujii, Joseph Leonetti
-
Patent number: 9267213Abstract: There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.Type: GrantFiled: April 30, 2014Date of Patent: February 23, 2016Assignee: CustomArray, Inc.Inventors: Karl Maurer, John J Cooper
-
Publication number: 20130341561Abstract: There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.Type: ApplicationFiled: March 12, 2013Publication date: December 26, 2013Applicant: CustomArray, Inc.Inventors: Karl Maurer, John J. Cooper, JR., Michael Strathmann
-
Patent number: 8373313Abstract: A switch for premises electrical circuits provides wireless control compatible with at least one home automation control system technology. A single switch design can operate two-, three-, and four-way circuits without alteration, and without recourse to coordinating remote switches. The switch includes processor functions for restoring a previous state after power interruption, and for establishing a state commanded during the power interruption. The switch uses two single-pole, single-throw relays for positive safety lockout, and adjusts relay actuation timing with reference to power waveform zero-crossing for contact arc reduction with inductive, tungsten, and capacitive loads.Type: GrantFiled: June 15, 2010Date of Patent: February 12, 2013Assignee: HomeRun Holdings CorporationInventors: Ben L. Garcia, Yan Rodriguez, Steven Karl Maurer
-
Publication number: 20110141647Abstract: A switch for premises electrical circuits provides wireless control compatible with at least one home automation control system technology. A single switch design can operate two-, three-, and four-way circuits without alteration, and without recourse to coordinating remote switches. The switch includes processor functions for restoring a previous state after power interruption, and for establishing a state commanded during the power interruption. The switch uses two single-pole, single-throw relays for positive safety lockout, and adjusts relay actuation timing with reference to power waveform zero-crossing for contact arc reduction with inductive, tungsten, and capacitive loads.Type: ApplicationFiled: June 15, 2010Publication date: June 16, 2011Applicant: HOMERUN HOLDINGS, CORP.Inventors: Ben L. Garcia, Yan Rodriguez, Steven Karl Maurer
-
Patent number: 7950436Abstract: A room darkening screen apparatus includes a shade roll. A shade with a first end and a second end is provided wherein the first end is connected with the shade roll and the second end is connected with a bottom bar. A header is connected with the shade roll and a folding rod is connected with the header such that the folding rod, when released from the header, folds the shade.Type: GrantFiled: December 4, 2008Date of Patent: May 31, 2011Assignee: Homerun Holdings CorporationInventors: Willis Jay Mullet, Christopher Lee Wysoczynski, Steven Karl Maurer, Richard Scott Hand, Doug Real, Darrin Anthony Trapani
-
Patent number: 7718579Abstract: A method for electrochemical removal of acid-labile protecting groups on an electrode microarray using an organic solution is disclosed. The solution comprises a hydrazine derivative and a salt in an organic solvent. The hydrazine derivative has at least one hydrazine group having at least one hydrogen. The hydrazine derivative provides acidic reagent when an electrode is active and isolates the acidic reagent to the area around the active electrode. The salt is an organic salt or ionic liquid having a concentration sufficient to provide electrochemical conductivity under an applied voltage. During the applied voltage, acidic reagent is generated, which removes acid-labile protecting groups thereby allowing continued addition of monomers to build a custom microarray of oligonucleotides, peptides, or other polymers.Type: GrantFiled: September 13, 2004Date of Patent: May 18, 2010Assignee: CombiMatrix CorporationInventor: Karl Maurer
-
Publication number: 20090280998Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.Type: ApplicationFiled: April 27, 2009Publication date: November 12, 2009Inventors: Karl Maurer, Dominic Suciu, Hetian Gao