Patents by Inventor Karthikeyan Murugesan

Karthikeyan Murugesan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200357491
    Abstract: In healthcare associated infection (HAI) outbreak tracking, different transmission tree inference algorithm processes (40) are performed on genetic variants data (26) for a set of HAI infected persons to generate a plurality of transmission trees (42) representing parent-child infectious transmission links. For each transmission tree, the value (44) of a correlation metric is computed, which measures correlation of the transmission tree with a clinical correlate (46). For each random trial of a plurality of random trials (52), the value (54) of the correlation metric is also computed. A statistical likelihood (60) of each transmission tree given the clinical correlate is estimated from the computed values of the correlation metric for the random trials and for the transmission tree. This may, for example, be a p-value. An optimal transmission tree is selected from amongst the plurality of transmission trees based on the estimated statistical likelihoods.
    Type: Application
    Filed: December 10, 2018
    Publication date: November 12, 2020
    Inventors: HENRY LIN, BRIAN DAVID GROSS, KARTHIKEYAN MURUGESAN
  • Publication number: 20200283908
    Abstract: A surface-protective coating forming composition exhibiting excellent shelf life (e.g. storage stability) and cured coating performance is derived from alkoxysilane and silica nanoparticles.
    Type: Application
    Filed: March 4, 2019
    Publication date: September 10, 2020
    Inventors: Rajkumar Jana, Raghavendra Prasad, Karthikeyan Murugesan
  • Publication number: 20200283657
    Abstract: A surface-protective coating forming composition exhibiting excellent shelf life (storage stability) and cured coating performance is derived from alkoxysilane and a plurality of metal oxides.
    Type: Application
    Filed: March 4, 2019
    Publication date: September 10, 2020
    Inventors: Rajkumar Jana, Raghavendra Prasad, Karthikeyan Murugesan
  • Publication number: 20200207992
    Abstract: A surface-protective coating forming composition exhibiting excellent shelf life (storage stability) and cured coating performance is derived from trialkoxysilane and metal oxide powder.
    Type: Application
    Filed: July 31, 2018
    Publication date: July 2, 2020
    Inventors: Rajkumar JANA, Christoph HILGERS, Indumathi RAMAKRISHNAN, Karthikeyan MURUGESAN, Wibke HARTLEB
  • Publication number: 20200152292
    Abstract: A system to identify genes that confer antibiotic resistance, comprising: a processor configured to: (i) identify a set of genes present in a sample of genome sequences sequenced from potentially pathogenic isolates; (ii) generate a genome sequence without the identified set of genes; (iii) generate a gene presence-absence matrix listing the genes present in each of the genome sequences, comprising an identification of each of the plurality of genes and an identification of each of the plurality of genome sequences, and comprising an identification of whether each of the genome sequences is obtained from an organism resistant to at least one antibiotic, and further comprising an identification of either presence or absence of the respective gene within the respective genome sequence; and (iv) identify at least one gene or mutation in the plurality of genome sequences associated with antibiotic resistance; and a user interface configured to provide a report.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Inventors: KARTHIKEYAN MURUGESAN, NEVENKA DIMITROVA, HENRY LIN, PRAMOD MAYIGOWDA
  • Patent number: 10629291
    Abstract: Methods and systems for identifying causal genetic mechanisms of antibiotic resistance in pathogens. In accordance with at least one embodiment, the system includes a gene resistance module to identify genes present in an antibiotic resistant pathogen, a single nucleotide polymorphism module to identify mutations present in an antibiotic resistant pathogen, and an antibiotic resistance module configured to output the causation of antibiotic resistance based on the identified genes and mutations.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: April 21, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Karthikeyan Murugesan, Nevenka Dimitrova, Henry Lin, Pramod Mayigowda
  • Publication number: 20200024475
    Abstract: Provided is a coating composition comprising (a) a component A of the formula (R1)dSi(OR2)4?d, wherein R1 is a C1-C3 monovalent hydrocarbon, R2 is an R1 or a hydrogen radical and d is 0, 1 or 2; (b) a component B selected from the group consisting of (R3)aSi(OR4)4?a (Formula 1) and/or (R5O)m(R6)nSi(R9)x(R10)y Si(R11)zSi(R)o(OR7)p (Formula 2); (c) metal oxide particles; (d) UV absorber; (e) a catalyst; and (f) a solvent. The coating composition may provide a coating exhibiting good optical properties as well as durability, abrasion resistance, and/or crack resistance.
    Type: Application
    Filed: July 23, 2018
    Publication date: January 23, 2020
    Inventors: Laxmi Samantara, Jennifer Lynn David, Indumathi Ramakrishnan, Robert Hayes, Karthikeyan Murugesan
  • Publication number: 20190279738
    Abstract: Methods and systems for predicting the susceptibility of bacterial pathogens to antibiotics using genomic data sets. Various embodiments described herein receive a genomic dataset and a set of labels and run principal variance component analysis thereon to determine the effect sizes of the labels. One or more labels are then selected based on their effect sizes and used in a machine learning model to make predictions on future datasets.
    Type: Application
    Filed: November 27, 2017
    Publication date: September 12, 2019
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventor: Karthikeyan MURUGESAN
  • Publication number: 20190031918
    Abstract: A surface-protective coating forming composition exhibiting excellent shelf like (storage stability) and cured coating performance is derived from trialkoxysilane and metal oxide powder.
    Type: Application
    Filed: July 31, 2017
    Publication date: January 31, 2019
    Inventors: Rajkumar JANA, Christoph HILGERS, lndumathi RAMAKRISHNAN, Karthikeyan MURUGESAN, Wibke HARTLEB
  • Publication number: 20180148600
    Abstract: The present technology provides a coating system including a curable silicone polymer and a catalyst, wherein the catalyst is selected from a super base, a salt of a super base, or a combination of two or more thereof.
    Type: Application
    Filed: June 27, 2017
    Publication date: May 31, 2018
    Inventors: Karthikeyan Murugesan, Karthikeyan Sivasubramanian, Indumathi Ramakrishnan, Sumi Dinkar, Vivek Khare, Robert Hayes
  • Publication number: 20180148601
    Abstract: The present technology provides a coating system including an inorganic UV-absorbing material and a catalyst. The inorganic UV-absorbing material is chosen from cerium oxide, titanium oxide, zinc oxide, or combinations of two or more thereof. The inorganic material may be provided ranging from 1 wt. % to about 50 wt. % based on the dry weight of film after curing the coating system. The catalyst is provided in an amount ranging from 1 ppm to about 75 ppm. The coating system may include a topcoat material, a primer material, or a combination thereof.
    Type: Application
    Filed: June 27, 2017
    Publication date: May 31, 2018
    Inventors: Karthikeyan Murugesan, Indumathi Ramakrishnan, Robert Hayes
  • Publication number: 20170369715
    Abstract: The present technology provides a coating system including a luminophoric material. The luminophoric material is a pyridine-containing ligand chosen from a substituted or unsubstituted bidentate pyridine compound, a substituted or unsubstituted tridentate pyridine compound, or a combination of two or more thereof. Alternatively, the luminophoric material may be a fluorescent dye. The coating system may include a topcoat material, a primer material, or a combination thereof.
    Type: Application
    Filed: December 29, 2015
    Publication date: December 28, 2017
    Inventors: Karthikeyan MURUGESAN, Karthikeyan SIVASUBRAMANIAN, Indumathi RAMAKRISHNAN, Vivek KHARE
  • Publication number: 20170270244
    Abstract: Methods and systems for identifying causal genetic mechanisms of antibiotic resistance in pathogens. In accordance with at least one embodiment, the system includes a gene resistance module to identify genes present in an antibiotic resistant pathogen, a single nucleotide polymorphism module to identify mutations present in an antibiotic resistant pathogen, and an antibiotic resistance module configured to output the causation of antibiotic resistance based on the identified genes and mutations.
    Type: Application
    Filed: March 9, 2017
    Publication date: September 21, 2017
    Inventors: Karthikeyan Murugesan, Nevenka Dimitrova, Henry Lin, Pramod Mayigowda
  • Publication number: 20170233590
    Abstract: A primer composition comprising metal oxide particles modified with an alkyltrialkoxy silane; an organic polymer; and a solvent. The weight ratio of alkyltrialkoxy silane to metal particles is at least 0.9:1. The primer compositions produce films having excellent optical and adhesion characteristics.
    Type: Application
    Filed: February 15, 2016
    Publication date: August 17, 2017
    Inventors: Raghuraman Govindan Karunakaran, Karthikeyan Murugesan, Indumathi Ramakrishnan, Robert Hayes
  • Publication number: 20150159036
    Abstract: The present invention is directed to a primer composition, comprising: (a) metal oxide nanoparticles surface-modified with an organofunctional silane moiety having a specific functionality, (b) an organic polymer; and (c) one or more solvents; wherein the composition comprises less than 4 wt % of water, based on the total weight of said primer composition. The composition produces films having excellent optical and adhesion characteristics, and excellent weatherability and thermal stability.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 11, 2015
    Applicant: Momentive Performance Materials Inc.
    Inventors: Karthikeyan Murugesan, Indumathi Ramakrishnan, Robert F. Hayes, Keith J. Weller